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Sensory neuron changes and Merkel-cell changes in the skin happen independently during normal skin maintenance.

Sensory neuron remodeling and Merkel-cell changes in the skin happen independently.

Sensory neuron remodeling and Merkel-cell changes happen independently during skin maintenance.

Sensory neuron and Merkel cell changes in the skin happen independently during normal skin maintenance.

Sensory neurons and Merkel cells remodel at different rates during normal skin maintenance.

Skin stem cells interacting with their environment is crucial for maintaining and regenerating skin and hair, and understanding this can help develop new treatments for skin and hair disorders.

Skin cells show flexibility in healing wounds and forming tumors, with potential for treating hair disorders and chronic ulcers.

Different hair follicles in the skin are innervated by unique combinations of mechanosensory neurons, crucial for touch sensation.

The document suggests that nerve issues might contribute to hair loss and that testing sensation could predict these nerve problems.

Understanding how hair follicle stem cells work can help find new ways to prevent hair loss and promote hair growth.

TRPV4 helps cells repair tissue and reduce scarring by controlling calcium levels.

New treatments for hair growth disorders are needed due to limited current options and complex hair follicle biology.

The Hedgehog signaling pathway is important for skin and hair growth and can lead to cancer if it doesn't work right.

Hair follicle stem cells help maintain skin health and could improve skin replacement therapies.

The document concludes that hair follicles have a complex environment and our understanding of it is growing, but there are limitations when applying animal study findings to humans.

Botanical extract improved well-being and skin health in a test group compared to a placebo.

The skin's basement membrane has specialized structures and molecules for different tissue interactions, important for hair growth and attachment.

The skin's basement membrane is specially designed to support different types of connections between skin layers and hair follicles.

Different whale and dolphin species have unique whisker follicle structures, suggesting they might use their whiskers in various ways.

Ptprq has multiple forms that change during inner ear development.

Mutations in the PTPRQ gene cause significant balance issues in mice due to hair bundle defects in the inner ear.

Skin's epithelial stem cells are crucial for repair and maintenance, and understanding them could improve treatments for skin problems.

The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.

Hair growth phase and certain genes can speed up wound healing, while an inflammatory mediator can slow down new hair growth after a wound. Understanding these factors can improve tissue regeneration during wound healing.

Different types of skin cells play specific roles in development, healing, and cancer.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

We need more research to better understand human hair follicle stem cells for improved treatments for hair loss and skin cancer.

The document concludes that adult mammalian skin contains multiple stem cell populations with specific markers, important for understanding skin regeneration and related conditions.

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.