140 citations,
February 2014 in “Neuron” Delta opioid receptors help regulate touch sensation by reducing neurotransmitter release in the spinal cord.
The transcription factor Meis2 is essential for touch sensation and proper nerve development in touch receptors.
307 citations,
November 1968 in “Journal of neurophysiology” Cats' hairy skin has different touch receptors connected by myelinated fibers.
July 2023 in “Research Square (Research Square)” Skin's uneven surface and hair follicles affect its stress and strain but don't change its overall strength, and help prevent the skin from peeling apart.
2 citations,
October 2023 in “Science advances” Touching hair can activate nearby nerve cells through signals from the hair's outer layer.
Meis2 is essential for touch sensation and proper nerve connection to touch receptors in certain skin areas of mice.
660 citations,
December 2011 in “Cell” Different hair follicles in the skin are innervated by unique combinations of mechanosensory neurons, crucial for touch sensation.
August 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” Mouse touch-sensitive nerve cells adjust their connections based on competition with other similar cells.
19 citations,
February 2016 in “Journal of Biological Chemistry” KCNQ potassium channels help control the sensitivity of touch receptors in the skin.
January 2022 in “Social Science Research Network” Potassium channel modulators mostly increase the activity of rat whisker mechanoreceptors.
Meis2 is essential for touch sensation and nerve function in mice.
21 citations,
April 1990 in “Journal of comparative neurology” The study found that nerve signals are stronger when there are more connection points, but not necessarily denser, along the nerve's path in the spine.
106 citations,
February 2014 in “eLife” Lanceolate complexes in mouse hair follicles are essential for touch and depend on specific cells for maintenance and regeneration.
April 2022 in “Journal of The American Academy of Dermatology” The document suggests that nerve issues might contribute to hair loss and that testing sensation could predict these nerve problems.
August 2023 in “Military Medical Research” Scientists have improved 3D models of human skin for research and medical uses, but still face challenges in perfectly replicating real skin.
19 citations,
November 2014 in “Journal of Comparative Physiology A” Spider joint hair sensilla are adapted to sense movement during walking.
6 citations,
December 2016 in “Journal of Obsessive-Compulsive and Related Disorders” Adults with trichotillomania do not have different pain sensitivity to cold pressor pain compared to healthy individuals.
4 citations,
January 2013 in “Humana Press eBooks” Scientists found ways to identify and collect skin stem cells, which vary by skin area and are delicate.
16 citations,
February 2022 in “Science Advances” Follistatin and LIN28B together improve the ability of inner ear cells in mice to regenerate into hearing cells.
11 citations,
December 2011 in “Biochemical journal” Neurotrophin-4 increases calcium current in specific mouse neurons through the PI3K pathway.
1 citations,
February 2020 in “Journal of Cosmetic Dermatology” Hair transplant surgery reduces scalp sensitivity by almost 40%, and smokers have less scalp sensitivity than non-smokers. The time since surgery doesn't significantly affect this.
5 citations,
March 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Dynamic, light touch is sensed through a common mechanism involving Piezo2 channels in sensory axons.
1160 citations,
November 2018 in “Physiological Reviews” The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.
September 2024 in “Journal of Investigative Dermatology” A new tool can analyze hair to detect changes due to hormones, genetics, and aging.
46 citations,
July 2007 in “Journal of comparative neurology” Manatee whiskers are specially adapted for touch in water.
7 citations,
June 2020 in “npj regenerative medicine” GDNF helps grow hair and heal skin wounds by acting on hair stem cells.
2 citations,
October 2017 Vibration anesthesia can significantly lessen the pain during hair restoration surgery.
January 2024 in “Archives of pharmacy practice” The skin is vital for protection, temperature control, fluid balance, immunity, and sensing, with damage affecting daily life and mental health.
Vibration anesthesia can significantly reduce pain during hair transplant surgery.
6 citations,
May 2020 in “Molecules/Molecules online/Molecules annual” Yak belly hair has higher porosity and is less stiff than human hair, making it absorb dye better but less suitable as a direct substitute for hair dyeing.