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    Glossary Mechanoreceptors

    specialized cells that detect mechanical pressure or distortion

    Mechanoreceptors are specialized sensory cells that respond to mechanical pressure or distortion. They play a crucial role in the sense of touch, detecting stimuli such as vibration, pressure, and stretch, and are found in various tissues, including the skin, muscles, and hair follicles.

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    Research 30 of 139

    1. KCNQ4 K+ channels tune mechanoreceptors for normal touch sensation in mouse and man Nature Neuroscience · 2011 · 109 citations
    2. KCNQ Potassium Channels Modulate Sensitivity of Skin Down-hair (D-hair) Mechanoreceptors Journal of Biological Chemistry · 2016 · 19 citations
    3. Three-dimensional microanatomy of mechanoreceptors and their possible mechanism of sensory transduction. PubMed · 2001 · 1 citations
    4. Follicle-innervating Aδ-low threshold mechanoreceptors organize through a population-dependent mechanism bioRxiv (Cold Spring Harbor Laboratory) · 2022
    5. Effects of camphor and related compounds on slowly adapting mechanoreceptors in the rat sinus hair follicle IBRO Neuroscience Reports · 2022 · 5 citations
    6. Effects of transient receptor potential (TRP) channel agonists and antagonists on slowly adapting type II mechanoreceptors in the rat sinus hair follicle Journal of the Peripheral Nervous System · 2009 · 13 citations
    7. Effects of Potassium Channel Modulators on the Responses of Mammalian Slowly Adapting Mechanoreceptors Social Science Research Network · 2022
    8. Receptor types in cat hairy skin supplied by myelinated fibers. Journal of neurophysiology · 1968 · 307 citations
    9. Delta Opioid Receptors Presynaptically Regulate Cutaneous Mechanosensory Neuron Input to the Spinal Cord Dorsal Horn Neuron · 2014 · 140 citations
    10. Three-dimensional analyses of touch domes in the hairy skin of the cat paw reveal morphological substrates for complex sensory processing Neuroscience Research · 2008 · 24 citations
    11. Skin-type-dependent development of murine mechanosensory neurons Developmental Cell · 2023 · 13 citations
    12. Ca <sup>2+</sup> -mediated protein citrullination regulates proliferation in the regenerating and malignant CNS 2026
    13. Author Response: Touch receptor end-organ innervation and function require sensory neuron expression of the transcription factor Meis2 2024
    14. The Role of Interface Geometry and Appendages on the Mesoscale Mechanics of the Skin Research Square (Research Square) · 2023
    15. The Functional Organization of Cutaneous Low-Threshold Mechanosensory Neurons Cell · 2011 · 660 citations
    16. Robust coupling between the C‐tactile afferent and the hair follicle in humans The Journal of Physiology · 2025 · 7 citations
    17. Mechanical stimulation of human hair follicle outer root sheath cultures activates adjacent sensory neurons Science advances · 2023 · 2 citations
    18. eLife assessment: Touch receptor end-organ innervation and function require sensory neuron expression of the transcription factor Meis2 2024
    19. Club-like receptors respond to light touch but not to whisking Nature Communications · 2025
    20. Correlation of monosynaptic field potentials evoked by single action potentials in single primary afferent axons and their bouton distributions in the dorsal horn Journal of comparative neurology · 1990 · 21 citations
    21. Intravital Two-Photon Imaging of Touch Sensory Axon Morphology in Mouse Skin 2025
    22. Different Requirements for GFRα2-Signaling in Three Populations of Cutaneous Sensory Neurons PLoS ONE · 2014 · 11 citations
    23. Author response: Spatiotemporal dynamics of PIEZO1 localization controls keratinocyte migration during wound healing 2021
    24. The structure and organization of lanceolate mechanosensory complexes at mouse hair follicles eLife · 2014 · 106 citations
    25. A Study of the Expression of Small Conductance Calcium-Activated Potassium Channels (SK1-3) in Sensory Endings of Muscle Spindles and Lanceolate Endings of Hair Follicles in the Rat PLoS ONE · 2014 · 17 citations
    26. TARSAL CONTACT CHEMOSENSORY HAIRS OF THE LARGE WHITE BUTTERFLY <i>PIERIS BRASSICAE</i> AND THEIR POSSIBLE RÔLE IN OVIPOSITION BEHAVIOUR Entomologia Experimentalis et Applicata · 1973 · 207 citations
    27. Wound Healing: A Cellular Perspective Physiological Reviews · 2018 · 1160 citations
    28. Large Scale Gene Expression Profiles of Regenerating Inner Ear Sensory Epithelia PLoS ONE · 2007 · 77 citations
    29. Modulatory role of vitamins A, B3, C, D, and E on skin health, immunity, microbiome, and diseases Pharmacological Reports · 2023 · 47 citations
    30. Tactile innervation densities across the whole body bioRxiv (Cold Spring Harbor Laboratory) · 2020 · 4 citations