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    Glossary Mechanoreceptors

    specialized cells that detect mechanical pressure or distortion

    Mechanoreceptors are specialized sensory cells that respond to mechanical pressure or distortion. They play a crucial role in the sense of touch, detecting stimuli such as vibration, pressure, and stretch, and are found in various tissues, including the skin, muscles, and hair follicles.

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    Research 30 of 158

    1. KCNQ4 K+ channels tune mechanoreceptors for normal touch sensation in mouse and man Nature Neuroscience · 2011 · 109 citations
    2. KCNQ Potassium Channels Modulate Sensitivity of Skin Down-hair (D-hair) Mechanoreceptors Journal of Biological Chemistry · 2016 · 19 citations
    3. Three-dimensional microanatomy of mechanoreceptors and their possible mechanism of sensory transduction. PubMed · 2001 · 1 citations
    4. Follicle-innervating Aδ-low threshold mechanoreceptors organize through a population-dependent mechanism bioRxiv (Cold Spring Harbor Laboratory) · 2022
    5. Sensations Evoked by Microstimulation of Single Mechanoreceptive Afferents Innervating the Human Face and Mouth Journal of Neurophysiology · 2010 · 63 citations
    6. Effects of camphor and related compounds on slowly adapting mechanoreceptors in the rat sinus hair follicle IBRO Neuroscience Reports · 2022 · 5 citations
    7. Effects of transient receptor potential (TRP) channel agonists and antagonists on slowly adapting type II mechanoreceptors in the rat sinus hair follicle Journal of the Peripheral Nervous System · 2009 · 13 citations
    8. Effects of Potassium Channel Modulators on the Responses of Mammalian Slowly Adapting Mechanoreceptors Social Science Research Network · 2022
    9. Receptor types in cat hairy skin supplied by myelinated fibers. Journal of neurophysiology · 1968 · 307 citations
    10. Delta Opioid Receptors Presynaptically Regulate Cutaneous Mechanosensory Neuron Input to the Spinal Cord Dorsal Horn Neuron · 2014 · 140 citations
    11. Three-dimensional analyses of touch domes in the hairy skin of the cat paw reveal morphological substrates for complex sensory processing Neuroscience Research · 2008 · 24 citations
    12. Skin-type-dependent development of murine mechanosensory neurons Developmental Cell · 2023 · 13 citations
    13. Ca <sup>2+</sup> -mediated protein citrullination regulates proliferation in the regenerating and malignant CNS 2026
    14. Author Response: Touch receptor end-organ innervation and function require sensory neuron expression of the transcription factor Meis2 2024
    15. The Role of Interface Geometry and Appendages on the Mesoscale Mechanics of the Skin Research Square (Research Square) · 2023
    16. Expression patterns of three estrogen receptor genes during zebrafish (Danio rerio) development: evidence for high expression in neuromasts Gene expression patterns · 2004 · 77 citations
    17. Characteristic intraepidermal nerve fibre endings of the intervibrissal fur in the mystacial pad of the rat: morphological details revealed by intravital methylene blue staining and the zinc iodide-osmium tetroxide technique Journal of Anatomy · 1999 · 5 citations
    18. Characteristic intraepidermal nerve fibre endings of the intervibrissal fur in the mystacial pad of the rat: morphological details revealed by intravital methylene blue staining and the zinc iodide‐osmium tetroxide technique Journal of Anatomy · 1999 · 5 citations
    19. The Functional Organization of Cutaneous Low-Threshold Mechanosensory Neurons Cell · 2011 · 660 citations
    20. Robust coupling between the C‐tactile afferent and the hair follicle in humans The Journal of Physiology · 2025 · 7 citations
    21. Mechanical stimulation of human hair follicle outer root sheath cultures activates adjacent sensory neurons Science advances · 2023 · 2 citations
    22. eLife assessment: Touch receptor end-organ innervation and function require sensory neuron expression of the transcription factor Meis2 2024
    23. Club-like receptors respond to light touch but not to whisking Nature Communications · 2025
    24. Correlation of monosynaptic field potentials evoked by single action potentials in single primary afferent axons and their bouton distributions in the dorsal horn Journal of comparative neurology · 1990 · 21 citations
    25. Intravital Two-Photon Imaging of Touch Sensory Axon Morphology in Mouse Skin 2025
    26. Different Requirements for GFRα2-Signaling in Three Populations of Cutaneous Sensory Neurons PLoS ONE · 2014 · 11 citations
    27. Author response: Spatiotemporal dynamics of PIEZO1 localization controls keratinocyte migration during wound healing 2021
    28. TARSAL CONTACT CHEMOSENSORY HAIRS OF THE LARGE WHITE BUTTERFLY <i>PIERIS BRASSICAE</i> AND THEIR POSSIBLE RÔLE IN OVIPOSITION BEHAVIOUR Entomologia Experimentalis et Applicata · 1973 · 207 citations
    29. The structure and organization of lanceolate mechanosensory complexes at mouse hair follicles eLife · 2014 · 106 citations
    30. A Study of the Expression of Small Conductance Calcium-Activated Potassium Channels (SK1-3) in Sensory Endings of Muscle Spindles and Lanceolate Endings of Hair Follicles in the Rat PLoS ONE · 2014 · 17 citations