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PF-05314882 selectively activates androgen receptors without much effect on prostate and may help in prostate cancer treatment and hair loss prevention.

Finding functions for unknown GPCRs is hard but key for making new drugs.

Tissue-derived extracellular vesicles are crucial for cancer diagnosis, prognosis, and treatment.

Thiocyanate helps hair growth and can be supplemented in diet or applied topically.

Two microRNAs affect hair follicle development in sheep by targeting specific genes.

New medications are improving depression treatment, emphasizing accurate diagnosis and chronic care.

Hutchinson-Gilford Progeria Syndrome causes rapid aging from a genetic mutation, with no cure but ongoing research into potential treatments.

High levels of cortisol in hair show long-term stress which can lower fertility in animals.

Moringa seed oil may help prevent hair loss and promote hair growth.

Alopecia Areata has no cure, treatments are limited, and the condition often recurs, but new therapies like JAK inhibitors show promise.

Hyaluronic acid injections improve skin thickness and quality, protecting against aging in rats.

Removing REDD1 in mice increases skin fat by making fat cells larger and more numerous.

Honey has many health benefits and is good for you.

Some drugs can cause reversible hair loss, but certain chemotherapy drugs may lead to permanent hair loss; drugs can also change hair color and texture.

Frontal Fibrosing Alopecia is a type of hair loss affecting mostly older women, with no agreed best treatment.

Glycogen metabolism is important for energy and processes in human hair follicles, and hair follicles may produce glucose from lactate.

Ginsenoside Rd may help improve skin aging by increasing collagen in the skin.

Mitochondrial dysfunction may contribute to chronic inflammation and immune system issues in Lichen planopilaris.

RPGRIP1L helps skin cells stick together by blocking PKCβII, which can prevent skin blistering like in pemphigus.

The document concludes that breast pain should be managed with personalized treatment, starting with non-drug methods and progressing to medication if necessary, while considering side effects and patient needs.

Teriflunomide is effective and generally safe for treating relapsing multiple sclerosis, reducing relapse rates and disability progression.

The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.

Vitiligo is a skin condition causing white spots, more common in women, often starts before age 20, and can affect mental health.

Hair growth is cyclic and influenced mainly by local factors.

Corticosteroids, especially prednisone, improve short-term muscle strength in Duchenne muscular dystrophy but have manageable side effects.

The bulletin provides guidelines for diagnosing and managing PCOS, suggesting weight loss, hormonal contraceptives, and diabetes screening, with clomiphene for infertility and various treatments for excess hair.

TRPA1 is crucial for mechanical sensitivity in skin sensory neurons.

Ectodin integrates BMP, SHH, and FGF signals in developing ectodermal organs.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

The document concludes that Catalyst software is effective for drug design, identifying potent compounds for various medical conditions.