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This narrative review from the authors discusses mechanical scalp stimulation as a potential treatment for androgenetic alopecia, suggesting it has a biologically plausible mechanism but immature clinical evidence; marketing of these devices currently outpaces their supporting data, indicating a need for better-controlled trials.

This narrative review suggests that while mechanical scalp stimulation has a plausible mechanism for aiding androgenetic alopecia, its clinical evidence is insufficient, and the marketing of stimulation devices currently outpaces their efficacy data.

This paper introduces the Vertex Overload Framework for androgenetic alopecia, suggesting that chronic mechanical and thermal stress on the vertex contributes to hair follicle miniaturization, with androgens acting as co-mediators of stress adaptation rather than isolated causes.

This study offers a new perspective on androgenetic alopecia, suggesting that hair loss at the vertex and frontal scalp results from mechanical and thermodynamic stress, alongside androgen activity, and proposes that reducing mechanical tension and improving local microcirculation could complement traditional treatments.

Mechanical tension worsens keloid scars by activating inflammation and fibrosis pathways.

This review discusses the role of mechanical forces in skin homeostasis and disease development, including their impact on conditions like keloids, androgenetic alopecia, and acral melanoma, and reports no clinical results; the authors propose modifying these forces as a potential therapeutic strategy.

This study suggests that mechanical stress may influence androgenic alopecia patterning through a stretch-induced and androgen-mediated mechanotransduction mechanism in dermal papilla cells.

This review discusses the mechanisms of wound healing and excessive scarring, highlighting the importance of understanding these processes for developing new therapies to prevent fibrotic scarring in large skin wounds.

This article describes cases of unusual scalp whorl patterns, including triple parietal and right temporal whorls, that were associated with normal development, and discusses theories of hair whorl development.

In this study, researchers observed that after mesenchymal cell division in mouse and chicken embryonic skin, elevated migration speed and persistence for 180 minutes contribute to mesenchymal dispersal and preferential recruitment to dermal condensates.

This study found that STRIP1 and the STRIPAK complex play a key role in regulating F-actin and cell-cell junctions, which are essential for maintaining the epidermal barrier in mouse skin.

This study suggests that mechanical tension significantly impacts lymphocyte function, and that a complete lymphocyte population is essential for effective wound healing and reducing inflammation.

This study presented a case series of erosive pustular dermatosis on the scalps of elderly patients, noting unusual presentation with hypergranulation tissue and unique dermoscopic vascular patterns, diverging from typical manifestations.

This chapter reviews traction alopecia, discusses its clinical presentation and severity grading, and reports no new clinical results; the authors highlight controversies in its treatment and prevention strategies.

This review highlights emerging evidence that biophysical and metabolic cues, such as oxygen levels and tissue mechanics, significantly influence skin stem cell behavior, which is crucial for developing advanced wound healing therapies beyond traditional infection and inflammation control.

This study found that filamin A plays a crucial role in fibroblasts' ability to sense and respond to mechanical stimuli, significantly affecting wound closure and fibroblast-mediated processes in mice.

This review discusses recent advances in scarless wound healing research, focusing on the roles of mechanobiology and immunology, and reports no new clinical results; the authors highlight the potential of next-generation human skin equivalents in understanding these mechanisms.

In this study, a mechanical model was developed to describe and validate the effectiveness of overnight hair curling, suggesting that combining it with hair fixatives can maintain a desired curl for over a day.

This study found that large excisional wounds in mice can regenerate new hair follicles and fat, whereas similar wounds in rats across seven strains failed to do so, highlighting interspecies differences in regenerative capacity.

This review discusses past research on the chemical and physical properties of human hair, focusing on structural analysis and mechanical property measurements with methods like SEM and tension tests, but adds no new findings.

This review highlights that surface mechanical regulation can program macrophage behavior through specific mechanical cues on material surfaces, potentially advancing immunotherapies and regenerative medicine by enabling precise control over macrophage functions.

This review discusses how fibroblast metabolic processes and life span are influenced by the malate dehydrogenase shuttle system and highlights factors affecting fibroblast proliferative activity, without presenting new experimental results.

This review examines the mechanisms behind pathological scarring like hypertrophic scars and keloids, highlights the limitations of current treatments, and suggests that biomaterial-enabled delivery of anti-fibrotic statins, such as atorvastatin, may offer a promising therapeutic avenue for managing these scars.

This study investigated the tensile response and morphological changes of different ethnic hair types using AFM, showing variations between virgin, chemically damaged, and conditioner-treated Caucasian hair under different conditions.

This study found that 3D microtissue models of dermal papilla cells can enhance the ability to induce hair-follicle neogenesis in vivo, offering potential for controlled cell production in follicle regeneration.

This study presents a new method for evaluating cosmetic treatments by measuring the resistance of hair to mechanical wear, revealing differences related to hair ethnicity and treatment type.

This study found that mechanical skin stretching can stimulate hair stem cell proliferation and hair regeneration by activating a complex pathway involving WNT, BMP-2, and M2 macrophages.

Stretching skin increases a certain protein that attracts stem cells, helping skin regeneration.

This case series reports successful treatment of refractory folliculitis decalvans using surgical excision with second-intention healing and guarded high-tension suturing, resulting in long-term remission without recurrence over a 10–24 month follow-up period.

This paper reviews various techniques for measuring the physical and mechanical properties of human hair fibers, emphasizing their importance in developing effective cosmetic products.