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Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

LED light therapy is effective for skin and hair treatments but requires careful use to minimize risks.

Combining CGF and microneedling with betamethasone effectively treats resistant alopecia areata.

Primary care is key in managing PCOS, focusing on lifestyle changes and medications like birth control and metformin.

Early onset and pustules indicate severe hair follicle inflammation, and while antibiotics help, the condition often worsens after treatment stops.

New physical methods like electrical currents, ultrasound, and microneedles show promise for improving drug delivery through the skin.

Direct vasodilators and sympatholytic agents are still useful for certain conditions despite being less common due to side effects and newer drugs.

TGase 3 helps build hair structure by forming strong bonds between proteins.

Anti-androgens can help manage some PCOS symptoms better than metformin but are not more effective than placebos or birth control pills for other symptoms.

Efficient delivery systems are needed for the clinical use of CRISPR-Cas9 gene editing.

New UVA-responsive nanocapsules effectively kill microorganisms in hair follicles when activated by light.

Obesity is linked to skin conditions like acanthosis nigricans and skin tags, which may indicate high insulin levels.

Hair greying is linked to reduced ATM protein in hair cells, which protects against stress and damage.

Syphilis is becoming more common and remains a major health problem due to challenges in prevention and treatment.

The skin microbiome helps heal wounds and can be targeted to improve healing.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

The bulletin provides guidelines for diagnosing and managing PCOS, suggesting weight loss, hormonal contraceptives, and diabetes screening, with clomiphene for infertility and various treatments for excess hair.

MRI can effectively image skin structures noninvasively.

Printing human stem cells and a special matrix during surgery can help grow new skin and hair-like structures in rats.

Minoxidil treats high blood pressure and side effects can be managed.

Excessive hair growth in women, often from high androgen levels, is usually caused by PCOS, and can be treated with hair removal, medication, and possibly weight loss.

Testosterone therapy in transgender men has both desired effects like increased muscle mass and potential health risks such as higher cardiovascular risk.

Melatonin directly affects mouse hair follicles and may influence hair growth.

Minoxidil effectively treats severe hypertension, but watch for side effects.

The study explains how minoxidil sulfate causes vasodilation in rabbits by opening potassium channels and inhibiting calcium channels.

Fungal infection was the main cause of hair loss in Egyptian children studied.

Western diet may cause male pattern baldness; low glycemic diet with magnesium could help.

The document concludes that permanent hair loss conditions are complex, require early specific treatments, and "secondary permanent alopecias" might be a more accurate term than "secondary cicatricial alopecia."

The document concludes that understanding health requires considering evolutionary perspectives on reproductive fitness, and recognizing the complexity of factors like diet, testosterone, and sexual orientation.

The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.