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In this study, knockout of B-raf and C-raf genes in mice showed they are not needed for early melanocyte development, but are crucial for maintaining melanocyte stem cells, as evidenced by hair graying due to stem cell depletion.

This review discusses the use of stem cells and stem cell-derived products in burn wound healing, highlighting various stem cell sources, associated signaling pathways, and delivery methods, but reports no new clinical results.

This review discusses the interactions between melanocyte stem cells and their niche in hair regeneration and repair, but reports no new results; recent studies on molecular pathways are highlighted.

This study found that mesenchymal stem cells, especially when injected intradermally, significantly accelerated wound healing in rats compared to chitosan treatment.

This review discusses how using hydrogels as a three-dimensional culture platform for mesenchymal stem cells might affect the production of extracellular vesicles, highlighting challenges in standardization and opportunities to boost EV yield via combined hydrogels and bioreactor methods.

This study found that skin mesenchymal stem cells from hidradenitis suppurativa patients overexpress proinflammatory and anti-inflammatory cytokines, suggesting their potential contribution to the disease's pathogenesis.

This review highlights the need for optimizing mesenchymal stromal/stem cell therapy through tailored in vitro strategies to unlock their full potential for treating specific diseases.

In this review, the authors discuss the potential for cell therapy, such as hematopoietic stem cell transplantation and mesenchymal stromal cells, to treat severe psoriasis unresponsive to biological therapies, while highlighting the associated risks, costs, and regulatory challenges.

This review article summarizes the potential role of advanced medical therapies—using genes, cells, and/or tissue engineering—in treating various types of alopecia, by examining clinical research, basic studies, and ongoing trials.

This review discusses the potential effectiveness of cell therapy for hair loss, highlighting promising early findings but emphasizing that more research is needed to explore specific therapies like autologous fat grafting and mesenchymal stem cells.

This study found that a lentiviral array of reporters can identify lineage-specific promoters and pathways in mesenchymal stem cell differentiation, aiding in the prediction of signaling pathway effects.

This study concluded that topical aloe vera promoted faster and better healing of deep second-degree burns in rats compared to mesenchymal stem cells.

This study found that treating a murine model of systemic lupus erythematosus with early and optimally dosed mesenchymal stem cells effectively suppressed disease severity.

This study found that immune cells, including T cells and macrophages, significantly influence stem cell behavior and tissue regeneration by secreting cytokines and inflammatory factors in mice.

Exosomes from stem cells may help treat hair loss.

This review discusses current stem cell technologies, their potential therapeutic uses, and imaging techniques for tracking transplanted cells, without reporting new experimental results.

This review examines the potential of mesenchymal stem/stromal cells in treating and possibly preventing allergic diseases, and reports no new clinical results.

This study found that human mesenchymal stem cells overexpressing JAM-A improved hair follicle structure and hair formation in mice by reducing abnormalities such as curved and zigzagged follicles.

This study explored the immune environment of the hair follicle's bulge region and suggested that its unique signaling may prevent melanoma formation by lacking necessary proinflammatory signals for full oncogenic transformation, indicating potential strategies for melanoma prevention by replicating this immune-privileged environment.

This study found that stress-induced signaling from the sympathetic nervous system in mice led to the depletion of stem cells in hair follicles, resulting in premature greying.

This article reviews how biomaterials and stem cells could advance regenerative medicine but does not report new results, emphasizing the potential of combining novel biomaterials with stem cells for effective therapies.

This study supports using mesenchymal stem cells cultured with collagen to accelerate skin wound healing in mice and canines, by enhancing epidermal repair and promoting factors essential for skin recovery.

In this review, researchers explored the potential of exosomes in cosmetics, skincare, tissue regeneration, and dermatological treatment, noting their promising ability to modulate cellular environments, potentially improving skin health and treating various skin conditions.

This study found that hair follicle mesenchymal stem cells are similar to bone marrow stem cells in most characteristics, but differ in their adipogenic and osteogenic differentiation capabilities, suggesting they may be a suitable source for adipogenesis research.

This study investigated optimizing the differentiation process of UC-MSCs into dermal papilla-like tissues for potential hair follicle therapy and highlighted the potential to reduce associated costs by evaluating cell density and growth factors.

This study found that wounds in sheep treated with mesenchymal stem cells and platelet-rich plasma showed improved healing, reduced inflammation and contraction, and better skin structure compared to untreated wounds.

This review discusses the role of various cells outside the hair follicle in regulating melanocyte stem cells and hair graying, but reports no new clinical results.

The researchers reported that using a concentrate of conditioned mesenchymal stem cells derived from the placenta accelerated wound healing and regeneration in laboratory animals with severe local radiation injuries.

This review explores how mesenchymal stem cells and their extracellular vesicles may treat various skin diseases by modulating immune responses and promoting healing, though further clinical trials are needed to confirm their safety and efficacy in practice.

In this study, researchers found that deleting the Bmi1 gene in murine melanocytes caused premature hair greying and loss of melanocyte lineage cells, highlighting BMI1's role in protecting melanocyte stem cells from stress and oxidative damage.