research PBX1-SIRT1 Positive Feedback Loop Attenuates ROS-Mediated HF-MSC Senescence and Apoptosis
PBX1 reduces aging and cell death in stem cells by boosting SIRT1 and lowering PARP1.
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research In Vitro and Clinical Evaluation of Umbilical Cord-Derived Mesenchymal Stromal Cell-Conditioned Media for Hair Regeneration
Umbilical cord-derived media is safe and effective for hair growth.
research An Open Label Clinical Trial of the JAK Inhibitor Tofacitinib for Alopecia Areata
Tofacitinib helped over half of the patients with severe hair loss regrow at least 50% of their hair.
research Adipose-Derived Stem/Stromal Cells in Regenerative Medicine
Fat tissue stem cells show promise for repairing different body tissues and are being tested in clinical trials.
research Wharton Jelly Hair in a Case of Umbilical Cord Stricture and Fetal Death
Fetal death was caused by umbilical cord stricture with hair growth in the Wharton jelly.
research Translational Research in the Generation of Therapeutic Medicine for Wound Healing: A Review
New therapies show promise for wound healing, but more research is needed for safe, affordable options.
research Mesenchymal Stem Cell-Derived Protein Extract Induces Periodontal Regeneration
MSC-protein helps regenerate gum tissue and bone.
research Stimulation by Exosomes from Hypoxia-Preconditioned Hair Follicle Mesenchymal Stem Cells Facilitates Mitophagy by Inhibiting the PI3K/AKT/mTOR Signaling Pathway to Alleviate Ulcerative Colitis
Exosomes from special stem cells help treat ulcerative colitis by reducing inflammation and stress.
research Early Skin Seeding Regulatory T Cells Modulate PPARγ-Dependent Skin Pigmentation
Early regulatory T cells are crucial for normal skin pigmentation.
research Stem Cells in Plastic Surgery and Aesthetic Medicine
Stem cells can improve wound healing, reduce scars, promote hair growth, rejuvenate skin, and enhance fat grafts in plastic surgery, but there are still some concerns.
research DNA Dioxygenases Tet1/2/3 Control Hair Matrix Keratinocyte Differentiation and Hair Shaft Shape via Regulation of Hair Keratin Gene Expression
The enzymes Tet1, Tet2, and Tet3 are important for the development of hair follicles and determining hair shape by controlling hair keratin genes.
research Comparison Treatment of Vitiligo by Co-Culture of Melanocytes Derived from Hair Follicle with Adipose-Derived Stem Cells with and without Narrowband UVB
Treating vitiligo with stem cells and melanocytes from hair, along with UVB light, works better than without the light.
research A Preview of Selected Articles
New treatments for hair loss, fertility, and wound healing are being explored.
research Dermal Niche Signaling and Epidermal Stem Cells
Skin health and repair depend on the signals between skin stem cells and their surrounding cells.
research Dermatologic Toxicities Associated with Chronic Gamma-Secretase Inhibitor Treatment for Desmoid Tumor
Most patients experienced mild to moderate skin problems during a trial for a desmoid tumor treatment.
research Surface Modification and Endothelialization of Biomaterials as Potential Scaffolds for Vascular Tissue Engineering Applications
Improving artificial vascular grafts requires better materials and surface designs to reduce blood clotting and support blood vessel cell growth.
research SKPs Derive from Hair Follicle Precursors and Exhibit Properties of Adult Dermal Stem Cells
SKPs are similar to adult skin stem cells and could help in skin repair and hair growth.
research The Dynamics of the Skin’s Immune System
The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.
research Recent Understandings of Biology, Prophylaxis, and Treatment Strategies for Hypertrophic Scars and Keloids
The document concludes that the understanding of scar formation is incomplete and current prevention and treatment for hypertrophic scars and keloids are not fully effective.
research Fibroblast Heterogeneity: Implications for Human Disease
Different types of fibroblasts play various roles in diseases and healing, and more research on them could improve treatments.
research Recent Advances in Electrospun Nanofibers for Wound Healing
New nanofiber technology improves wound healing by supporting cell growth and delivering treatments directly to the wound.
research Stem Cells in Skin Regeneration, Wound Healing, and Their Clinical Applications
Stem cells are crucial for skin repair and new treatments for chronic wounds.
research Skin Cell Heterogeneity in Development, Wound Healing, and Cancer
Different types of skin cells play specific roles in development, healing, and cancer.
research Stem Cell Niches in Mammals
Stem cell niches are crucial for regulating stem cell renewal and differentiation, and understanding them can help in developing regenerative therapies.
research A Therapeutic Microneedle Patch Made from Hair-Derived Keratin for Promoting Hair Regrowth
A new microneedle patch made from hair proteins helps regrow hair faster and better than current treatments.
research The PDGF/PDGFR Pathway as a Drug Target
The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.
research Epigenetic Control of Adult Stem Cell Function
Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.
research In Vivo Transcriptional Governance of Hair Follicle Stem Cells by Canonical Wnt Regulators
Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.
research What Does the Concept of the Stem Cell Niche Really Mean Today?
Stem cell niches support, regulate, and coordinate stem cell functions.
research Bioprinting of Skin Constructs for Wound Healing
Bioprinting could improve wound healing but needs more development to match real skin.