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Different types of sun exposure damage skin cells and immune cells, with chronic exposure leading to more severe and lasting damage.

Damaging mitochondrial DNA in mice speeds up aging due to increased reactive oxygen species, not through the p53/p21 pathway.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Stem cell niches are crucial for regulating stem cell renewal and differentiation, and understanding them can help in developing regenerative therapies.

Inactive hair follicle stem cells help prevent skin cancer.

Hair loss can be reversed or even cured using advanced hair restoration techniques, with rare complications like swelling and bleeding.

Human hair follicle cells can be turned into neural stem cell-like cells, which might help treat brain diseases.

Adding L-glutamine to the diet of Hanwoo steers may boost their immune system and help them cope with heat.

Mutations in iRhom2 affect hair and skin in mice and are linked to esophageal cancer, with ADAM17 playing a crucial role.

Skin cell types develop when specific genes are turned on by removing certain chemical tags from DNA.

The skin's dermal layer contains true stem cells with diverse functions and interactions that need more research to fully understand.

The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.

Fat cells help recruit healing cells and build skin structure during wound healing.

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.

Mice studies show that Protein Phosphatase 2A is crucial for cell growth, development, and disease prevention.

Mammals might fail to regenerate not because they lack the right cells, but because of how cells respond to their surroundings, and changing this environment could enhance regeneration.

Changes to the Foxp3 protein affect how well regulatory T cells can control the immune system, which could help treat immune diseases and cancer.

Researchers created a fully functional, bioengineered skin system with hair from stem cells that successfully integrated when transplanted into mice.

The circadian clock influences the behavior and regeneration of stem cells in the body.

Researchers developed a method to grow hair follicle cells for transplantation using a special chip.

Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.

Emu oil may slow down skin healing but increases hair growth in burn wounds.

Placental mesenchymal stem cells and their conditioned medium significantly improve healing in local radiation injuries.

The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.

The supplement highlighted advancements and challenges in plastic and reconstructive surgery, including the impact of smoking, chemotherapy, and new treatments like Tafluprost for hair loss.

New treatments for male hypogonadism are effective and should be personalized.

New treatments for skin and hair repair show promise, but further improvements are needed.

The paper concludes that understanding melanocyte development can help in insights into skin diseases and melanoma diversity.

Fat cells in the skin help start healing and form important repair cells after injury.

Hair loss due to scarring can be treated by reducing inflammation, removing scar tissue, and transplanting hair. The Follicular Unit Extraction technique is effective but requires skill and time. Future focus should be on scar-less healing methods.