research Evidence for Multiple, Developmentally Regulated Isoforms of Ptprq on Hair Cells of the Inner Ear
Ptprq has multiple forms that change during inner ear development.
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research Update on Melasma—Part I: Pathogenesis
Melasma's causes include genetics, sun exposure, hormones, and oxidative stress, and understanding these can help create better treatments.
research Therapeutic Potential of Hair Follicle-Derived Stem Cell Intranasal Transplantation in a Rat Model of Ischemic Stroke
Transplanted hair follicle stem cells improved brain function and reduced damage after a stroke in rats.
research Effect of Decellularized Extracellular Matrix Bioscaffolds Derived from Fibroblasts on Skin Wound Healing and Remodeling
A patch made from human lung fibroblast material helps heal skin wounds effectively, including diabetic ulcers.
research Fine Structure of Marsupial Hairs, with Emphasis on Trichohyalin and the Structure of the Inner Root Sheath
Marsupial hair structure and keratin distribution are similar to placental mammals.
research The Pioneer Factor SOX9 Competes for Epigenetic Factors to Switch Stem Cell Fates
SOX9 helps determine stem cell roles by interacting with DNA and proteins that control gene activity.
research Coenzyme Q10 Has Anti-Aging Effects on Human Hair
Coenzyme Q10 helps reduce aging in human hair.
research Targeted Knockout of β-Catenin in Adult Melanocyte Stem Cells Using a Mouse Line, Dct::CreERT2, Results in Disrupted Stem Cell Renewal and Pigmentation Defects
The study used Dct::CreERT2 transgenic mice to explore the role of β-catenin in melanocyte stem cell (McSC) renewal and pigmentation. Knocking out β-catenin in McSCs led to disrupted stem cell renewal and pigmentation defects, causing permanent hair whitening in the mice. This demonstrated that β-catenin was essential for McSC renewal and mature melanocyte production. The findings highlighted a previously unreported function of β-catenin in McSC renewal, and the Dct::CreERT2 mouse line was established as a valuable tool for studying adult McSCs and pigmentation.
research CARI ONE Induces Anagen Phase of Telogenic Hair Follicles Through Regulation of β-Catenin, Stimulation of Dermal Papilla Cell Proliferation, and Melanogenesis
CARI ONE helps start hair growth and makes hair follicles bigger and more numerous.
research Autophagy Controls the Protein Composition of Hair Shafts
Autophagy changes the protein makeup of hair.
research Stem Cells, Organoids and Their Applications for Human Diseases: Special Issue of BMB Reports in 2023
Organoids created from stem cells are used to model diseases, test drugs, and develop personalized and regenerative medicine.
research Hair Regeneration Effects of Lespedeza Bicolor Extract In Vivo and In Vitro
Lespedeza bicolor extract promotes hair growth and increases hair follicle cell growth, potentially making it a better treatment than minoxidil.
research Moxibustion Improves Ovarian Function Based on the Regulation of the Androgen Balance
Moxibustion may help improve ovarian function by changing androgen levels.
research Scaling Dermatosis in Three Dogs Associated with Abnormal Sebaceous Gland Differentiation
Three dogs with a rare skin condition improved with treatment.
research Single-Cell Transcriptome Sequence Profiling on the Morphogenesis of Secondary Hair Follicles in Ordos Fine-Wool Sheep
The research identifies genes linked to wool quality in sheep and provides insights to improve wool production.
research Hair Loss, Body Height and Attractiveness Malus for Men
Men with hair loss are seen as less attractive and shorter, and height is a key factor in attractiveness ratings.
research Pilomatricoma With Florid Osseous Metaplasia: A Cytologist’s Perspective
A rare skin tumor with bone formation was successfully removed without recurrence.
research Autophagy Controls the Protein Composition of Hair Shafts
Autophagy is important for determining the protein makeup of hair.
research Alopecia Totalis in an Infant
An infant with complete hair loss was diagnosed with a genetic disorder affecting hair growth.
research Guiding Skin Organoid Generation via Extracellular Matrix Cues and Spatially Controlled Morphogen Gradients
Scientists improved how to make skin-like structures from stem cells using special gels and a device that controls growth signals, leading to better hair and skin features.
research Autophagy Protects Murine Preputial Glands Against Premature Aging and Controls Their Sebum Phospholipid and Pheromone Profile
Autophagy helps mouse glands stay healthy, prevents early aging, and maintains their oil and scent production.
research Neutrophil Extracellular Traps Impair Regeneration
Neutrophil extracellular traps slow down hair follicle healing after injury.
research Bilateral Squamous Cell Carcinoma of the Forehead
A 70-year-old man with skin cancer on both sides of his forehead was treated with surgery and cryotherapy, highlighting the need for early detection and prevention.
research Early and Late Matrix Progenitors Form the Terminally Differentiated Cell Layers of the Hair Follicle
Early and late matrix progenitors in hair follicles create different cell layers, with early ones forming the companion layer and later ones forming the inner root sheath and hair shaft.
research Hair Transplantation in Cicatricial Alopecia: A Preliminary Report
Hair transplantation is safe and effective for permanent hair loss due to scarring, with high patient satisfaction.
research The Morphological Structure of Female Telogen Effluvium and Alopecia Areata Hairs According to Curriculum Contents of Beauty Art Department
The study confirmed that changes in hair structure in women with hair loss conditions matched what is taught in beauty college trichology courses.
research Male Pattern Baldness: Causes, Treatments, and Future Prospects
Most American men experience hair loss by age 50, with limited effective treatments available and new options not expected soon.
research Editors' Picks
New findings suggest targeting IL-23 could treat psoriasis, skin cells can adapt to new roles, direct conversion of skin cells to blood cells may aid cell therapy, removing certain tumor cells could boost cancer immunotherapy, and melanoma may have many tumorigenic cells, not just cancer stem cells.
research Scalp Reduction Revisited: A 10-Year Experience
Scalp reduction surgery is safe and effective for certain patients with hair loss, leading to dense hair coverage and high satisfaction.
research Spatiotemporal Dynamics of Sensory Neuron and Merkel-Cell Remodeling During Epidermal Homeostasis
Sensory neuron remodeling and Merkel-cell changes happen independently during skin maintenance.