research Interrelation of Immunity and Tissue Repair or Regeneration
The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.
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research 5α-Reductase Activity in the Prostate
Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.
research ATP-Dependent Chromatin Remodeling During Mammalian Development
ATP-dependent chromatin-remodeling complexes are crucial for gene regulation, cell differentiation, and organ development in mammals.
research Cartilage to Bone Transformation During Fracture Healing Is Coordinated by the Invading Vasculature and Induction of the Core Pluripotency Genes
Blood vessels and specific genes help turn cartilage into bone when bones heal.
research Prevention of Chemotherapy-Induced Alopecia in Rats by CDK Inhibitors
Using CDK inhibitors on rats showed a reduction in chemotherapy-caused hair loss, but later experiments could not repeat these results.
research Adult Polycystic Ovary Syndrome Begins in Childhood
Polycystic Ovary Syndrome likely starts in childhood and may be genetic and influenced by early hormone exposure.
research MIM and Cortactin Antagonism Regulates Ciliogenesis and Hedgehog Signaling
MIM is crucial for hair follicle formation and regeneration by controlling cilia formation and hedgehog signaling through its interaction with Cortactin and Src.
research Zinc: An Essential Trace Element for Parenteral Nutrition
Zinc is crucial for nutrition, especially in patients with specific health conditions, and requires careful supplementation and monitoring.
research Regulatory T Cells in Skin: Role of Foxp3+ CD4+ Tregs in Skin Homeostasis and Immune Tolerance
Skin's Regulatory T cells are crucial for maintaining skin health and could be targeted to treat immune-related skin diseases and cancer.
research Pharmacology of Antiandrogens
Antiandrogens affect androgen-dependent body functions and are used for various medical conditions, with some risks like fetus feminization, but new forms like 17α-propylmesterolone show promise for acne without systemic effects.
research Stratum Corneum Dysfunction in Dandruff
Improving skin barrier and using antifungal treatments can help manage dandruff.
research FOXO1, TGF-β Regulation and Wound Healing
FOXO1 is important for wound healing, but its dysfunction in diabetes can slow the healing process.
research Genome-Wide Association Study Identifies a New Locus JMJD1C at 10q21 That May Influence Serum Androgen Levels in Men
A new gene, JMJD1C, may affect testosterone levels in men.
research Management of Acne
Acne treatment varies, with topical and systemic therapies effective, and more research needed on treatment order and long-term effects.
research Trichomegaly of the Eyelashes Following Treatment with Cetuximab
Cetuximab can cause excessive eyelash growth.
research Adverse Effects of Common Medications on Male Fertility
Some common medications can harm male fertility, but many effects can be reversed.
research Zinc Deficiency and Its Management in the Pediatric Population: A Literature Review and Proposed Etiologic Classification
Zinc deficiency in children can cause skin issues and can be serious if not diagnosed and treated properly.
research Aging of the Hair Follicle Pigmentation System
Hair grays due to oxidative stress and fewer functioning melanocytes.
research Physical Changes, Laboratory Parameters, and Bone Mineral Density During Testosterone Treatment in Adolescents with Gender Dysphoria
Testosterone treatment effectively causes male physical development in transgender male adolescents but may lead to side effects like acne, higher BMI and blood pressure, lower good cholesterol, and decreased bone density.
research Dermal Papilla Cells Improve Wound Healing and Generate Hair Bud-Like Structures in Grafted Skin Substitutes Using Hair Follicle Stem Cells
Dermal papilla cells help wounds heal better and can potentially grow new hair.
research Aberrant Activation of the Hedgehog Signaling Pathway in Malignant Hematological Neoplasms
Abnormal Hedgehog signaling in blood cancers may help tumors grow and resist chemotherapy, suggesting potential for targeted treatments.
research The Silver Locus Product (Silv/gp100/Pmel17) as a New Tool for the Analysis of Melanosome Transfer in Human Melanocyte–Keratinocyte Co-Culture
The new assay can track and measure melanosome transfer between skin cells, confirming filopodia's role in this process.
research Endocrine Influences on Hair Growth
Hormones and genetics affect hair growth and patterns, with some changes reversible and others not.
research Emerging Nonmetabolic Functions of Skin Fat
Skin fat has important roles in hair growth, skin repair, immune defense, and aging, and could be targeted for skin and hair treatments.
research Expression of mRNA for Androgen Receptor, 5α-Reductase, and 17β-Hydroxysteroid Dehydrogenase in Human Dermal Papilla Cells
Hair sensitivity to androgens is partly controlled by specific enzyme expressions in different hair areas.
research Androgen Action in the Ovary
Androgens are important for normal ovarian function and estrogen production, but may not be the main cause of follicle death.
research Gene Expression During Drosophila Wing Morphogenesis and Differentiation
Key genes are crucial for Drosophila wing development and could be insecticide targets.
research Steroids And Steroid-Like Compounds
Athletes use steroids to enhance performance despite health risks and legal issues, and education on their dangers is needed.
research BLIMP1 Is Required for Postnatal Epidermal Homeostasis but Does Not Define a Sebaceous Gland Progenitor Under Steady-State Conditions
BLIMP1 is essential for skin maintenance but not for defining sebaceous gland progenitors.
research Polycystic Ovary Syndrome: Early Detection in Adolescents
Early detection and treatment of PCOS in teenagers is important to manage symptoms and prevent severe issues.