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    Glossary Matrix Cells

    specialized cells that generate new hair growth

    Matrix cells are specialized cells located at the base of the hair follicle, within the hair bulb. These cells are responsible for producing the hair shaft and the inner root sheath through rapid cell division and differentiation. Essentially, they are the "building blocks" that generate new hair growth.

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    1. Dihydrotestosterone-Inducible IL-6 Inhibits Elongation of Human Hair Shafts by Suppressing Matrix Cell Proliferation and Promotes Regression of Hair Follicles in Mice Journal of Investigative Dermatology · 2011 · 173 citations
    2. Experimental Modulation of the Differentiated Phenotype of Keratinocytes from Epidermis and Hair Follicle Outer Root Sheath and Matrix Cells Annals of the New York Academy of Sciences · 1991 · 31 citations
    3. Extracellular Matrix as a Regulator of Epidermal Stem Cell Fate International Journal of Molecular Sciences · 2018 · 57 citations
    4. Stem cell factor combined with matrix proteins promotes attachment and migration of amelanotic melanocyte from human follicle hair Linchuang pifuke zazhi · 2006
    5. Hair matrix germinative epidermal cells confer follicle-inducing capabilities on dermal sheath and high passage papilla cells Development · 1996 · 61 citations
    6. Phenotypic modulation of human hair matrix cells (trichocytes) by environmental influence in vitro and in vivo. PubMed · 1993 · 11 citations
    7. 613 Assessment of the induction and morphogenic potential of human hair matrix cells and dermal papilla fibroblasts ex vivo Journal of Investigative Dermatology · 2019 · 1 citations
    8. Extracellular Matrix Degradation Products and Low-Oxygen Conditions Enhance the Regenerative Potential of Perivascular Stem Cells Tissue Engineering Part A · 2010 · 91 citations
    9. The enhancement of dermal papilla cell aggregation by extracellular matrix proteins through effects on cell–substratum adhesivity and cell motility Biomaterials · 2009 · 44 citations
    10. A Fibrous Hybrid Patch Couples Cell-Derived Matrix and Poly(l-lactide-<i>co</i>-caprolactone) for Endothelial Cells Delivery and Skin Wound Repair ACS Biomaterials Science & Engineering · 2018 · 16 citations
    11. Knockout of integrin β1 in induced pluripotent stem cells accelerates skin-wound healing by promoting cell migration in extracellular matrix Stem Cell Research & Therapy · 2022 · 3 citations
    12. γδ17 T cell-stromal networks modulate matrix composition and vascularity in foreign body response 2026 · 1 citations
    13. Enhancement of hair growth through stimulation of hair follicle stem cells by prostaglandin E2 collagen matrix Experimental cell research · 2022 · 1 citations
    14. Influence Of Extracellular Matrix On The Proliferation And Adhesion Properties Of Stem Cells Derived From Different Sources 2017 · 1 citations
    15. 085 Dermal papilla cells control hair follicle matrix keratinocytes proliferation through versican Journal of Investigative Dermatology · 2024
    16. The role of cell–cell and cell–matrix junctional complexes in sebaceous gland homeostasis and differentiation Cell Communication and Signaling · 2024 · 6 citations
    17. 877 Integration of magnetic tweezers and traction force microscopy for exploring the mechanobiology of keratinocyte cell-cell and cell-matrix anchoring junctions Journal of Investigative Dermatology · 2018
    18. Use of extracellular matrix hydrogel from human placenta to restore hair-inductive potential of dermal papilla cells Regenerative Medicine · 2019 · 31 citations
    19. Activin B Stimulates Mouse Vibrissae Growth and Regulates Cell Proliferation and Cell Cycle Progression of Hair Matrix Cells through ERK Signaling International Journal of Molecular Sciences · 2019 · 23 citations
    20. HAIR MATRIX CELL KINETICS: A SELECTIVE REVIEW International Journal of Dermatology · 1978 · 20 citations
    21. miR-140-5p in Small Extracellular Vesicles From Human Papilla Cells Stimulates Hair Growth by Promoting Proliferation of Outer Root Sheath and Hair Matrix Cells Frontiers in cell and developmental biology · 2020 · 18 citations
    22. β-Catenin is involved in oleanolic acid-dependent promotion of proliferation in human hair matrix cells in an in vitro organ culture model Fitoterapia · 2017 · 14 citations
    23. Cultivation of Hair Matrix Cells from Cashmere Goat Skins and Exemplified Applications Animals · 2020 · 3 citations
    24. Porcine acellular dermal matrix facilitates hair follicle stem cells entering the hair cycle in C57/BL6 mice Materialia · 2026
    25. Immunolocalization of telomerases in human hairs identifies proliferating cells in the bulb matrix and outer root sheath 2024
    26. Acquired curved hair is caused by fusion of multiple hair matrix cells Journal of Dermatological Science · 2024
    27. Transcriptomic Analysis Reveals Candidate Ligand-Receptor Pairs and Signaling Networks Mediating Intercellular Communication between Hair Matrix Cells and Dermal Papilla Cells from Cashmere Goats Cells · 2023
    28. Comparative Analysis of mRNA and miRNA Expression between Dermal Papilla Cells and Hair Matrix Cells of Hair Follicles in Yak Cells · 2022
    29. Differences in Hair Follicle Dermal Papilla Volume are Due to Extracellular Matrix Volume and Cell Number: Implications for the Control of Hair Follicle Size and Androgen Responses Journal of Investigative Dermatology · 1999 · 231 citations
    30. Proliferation and differentiation of organoid hair follicle cells co-cultured with fat cells in collagen gel matrix culture British Journal of Dermatology · 1998 · 30 citations