research Dermal Fibroblasts in Cutaneous Development and Healing
Skin cells called dermal fibroblasts are important for skin growth, hair growth, and wound healing.
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research The Origins of Skin Diversity: Lessons From Dermal Fibroblasts
New research shows that skin diversity is influenced by different types of dermal fibroblasts and their development, especially involving the Wnt/β-catenin pathway.
research Deficiency of Crif1 in Hair Follicle Stem Cells Retards Hair Growth Cycle in Adult Mice
Lack of Crif1 in hair follicle stem cells slows down hair growth in mice.
research Therapeutic Values of Exosomes in Cosmetics, Skin Care, Tissue Regeneration, and Dermatological Diseases
Exosomes could be effective for improving skin health and treating skin diseases.
research Human Teeth Are Useful Even After They Are Shed: Why Discard Them?
Baby teeth stem cells can potentially grow organs and treat diseases.
research MSCs and Their Exosomes: A Rapidly Evolving Approach in the Context of Cutaneous Wound Therapy
MSCs and their exosomes may speed up skin wound healing but need more research for consistent use.
research The Pathobiology of Skin Aging
Skin aging is a complex process influenced by various factors, leading to wrinkles and sagging, and should be considered a disease due to its health impacts.
research TGFβ Signaling Regulates Lipogenesis in Human Sebaceous Gland Cells
TGFβ signaling prevents sebaceous gland cells from producing fats.
research Dermal Adipose Tissue Secretes HGF to Promote Human Hair Growth and Pigmentation
Fat under the skin releases HGF which helps hair grow and gain color.
research Integrated miRNA-mRNA Analysis Reveals Regulatory Pathways Underlying the Curly Fleece Trait in Chinese Tan Sheep
Researchers found genes and microRNAs that control curly fleece in Chinese Tan sheep.
research Human Hair Follicle-Derived Mesenchymal Stromal Cells from the Lower Dermal Sheath as a Competitive Alternative for Immunomodulation
Cells from the lower part of hair follicles are a promising, less invasive option for immune system therapies.
research The Molecular Anatomy of Cashmere Goat Hair Follicle During Cytodifferentiation Stage
Understanding hair follicle development can help improve cashmere quality.
research The Molecular Revolution in Cutaneous Biology: Noncoding RNAs as New Molecular Players in Dermatology and Cutaneous Biology
Non-coding RNAs are crucial for skin development and health.
research Smad7-Induced Beta-Catenin Degradation Alters Epidermal Appendage Development
Too much Smad7 changes skin and hair development by breaking down a protein called β-catenin, leading to more oil glands and fewer hair follicles.
research Sox21 Regulates Anapc10 Expression and Determines the Fate of Ectodermal Organs
Sox21 is crucial for tooth development and enamel formation by preventing cells from changing into a different type.
research A Function for Rac1 in the Terminal Differentiation and Pigmentation of Hair
Rac1 is essential for proper hair structure and color.
research BMP2-Mediated PTEN Enhancement Promotes Differentiation of Hair Follicle Stem Cells by Inducing Autophagy
BMP2 helps hair follicle stem cells become specialized by increasing PTEN, which causes autophagy.
research Role of Cholesterol Sulfate in Epidermal Structure and Function: Lessons from X-Linked Ichthyosis
Cholesterol sulfate buildup due to a genetic mutation disrupts the skin barrier, leading to the scaling skin seen in X-linked ichthyosis.
research Progressive Alopecia Reveals Decreasing Stem Cell Activation Probability During Aging of Mice with Epidermal Deletion of DNA Methyltransferase 1
Mice lacking a key DNA methylation enzyme in skin cells have a lower chance of activating stem cells necessary for hair growth, leading to progressive hair loss.
research Epidermal Stem Cell Fate: What Can We Learn from Embryonic Stem Cells?
Embryonic and adult stem cells are valuable for improving skin grafts and cell therapy.
research Skin Cell Heterogeneity in Development, Wound Healing, and Cancer
Different types of skin cells play specific roles in development, healing, and cancer.
research What Does the Concept of the Stem Cell Niche Really Mean Today?
Stem cell niches support, regulate, and coordinate stem cell functions.
research Compartmentalized Organization: A Common and Required Feature of Stem Cell Niches?
Compartmentalized organization might be crucial for stem cells to effectively respond to growth or injury.
research Review of Human Hair Follicle Biology: Dynamics of Niches and Stem Cell Regulation for Possible Therapeutic Hair Stimulation for Plastic Surgeons
Understanding hair follicle biology and stem cell control could lead to new hair loss treatments.
research Tsukushi Is Involved in Wound Healing by Regulating the Expression of Cytokines and Growth Factors
Tsukushi helps control inflammation and aids in wound healing.
research Connecting Signaling Dynamics With Cell Fates In Live Mice
Stem cells control their future role by changing ERK signal timing, affecting tissue regeneration and cancer.
research Adipocyte Lineage Cells Contribute to the Skin Stem Cell Niche to Drive Hair Cycling
Fat-related cells are important for initiating hair growth.
research Pioneer Factors Govern Super-Enhancer Dynamics in Stem Cell Plasticity and Lineage Choice
Super-enhancers controlled by pioneer factors like SOX9 are crucial for stem cell adaptability and identity.
research Hair Follicle Stem Cell Proliferation, Akt and Wnt Signaling Activation in TPA-Induced Hair Regeneration
TPA promotes hair growth by increasing stem cell activity and activating specific cell signals.
research Keratin and Skin Disorders
Changes in keratin affect skin health and can lead to skin disorders like blistering diseases and psoriasis.