April 2019 in “Journal of Investigative Dermatology” In this study, researchers found that canonical Wnt/β-catenin signaling and Wnt-ligand expression are distinctly regulated during wound healing across different cell populations and immunity conditions, particularly under type 2 immunity.
5 citations
,
March 2019 in “International Journal of Endocrinology” In this study, the combination of exercise and finasteride improved ovarian morphology and hormone levels in rats with polycystic ovary syndrome more effectively than either treatment alone.
September 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that deleting all three Tet genes in mice led to shorter hair shafts and altered hair types, with associated changes in gene expression and DNA hydroxymethylation.
8 citations
,
July 2012 in “Annals of biomedical engineering” This study found that the uptake of molecules by hair is influenced by both hydrophobic and ionic charge interactions, with binding affinity decreasing as pH approaches the solute's dissociation constant.
6 citations
,
April 2024 in “Journal of Investigative Dermatology” This review highlights recent advances in CRISPR-based lineage tracing methods that can improve our understanding of skin stem cell behavior, regeneration, and disease, with potential applications in organoids and model organisms.
1 citations
,
April 2021 in “Journal of Investigative Dermatology” This study found that laboratory and African spiny mice have distinct spatiotemporal patterns in wound-induced hair neogenesis, with the Twist1 pathway playing a central role in epidermal-dermal interactions for hair primordia formation.
May 2018 in “Journal of Investigative Dermatology” Activating Wnt in skin cells controls the number of hair follicles by directing cell movement and fate.
October 2020 in “Misr journal of agricultural engineering” This study examined the drying of pomegranate peel as a method for reducing waste and found that drying efficiency varied with temperature and air velocity, potentially adding value to this by-product.
129 citations
,
May 2015 in “Cell Stem Cell” This review discusses recent findings on the plasticity and regulation of epithelial stem cells and reports no new experimental results.
67 citations
,
January 2020 in “Cellular & Molecular Immunology/Cellular & molecular immunology” This review discusses the dual role of tissue-resident memory T cells in providing immune protection against infections and cancer and contributing to autoimmune skin disease pathology, without presenting new experimental results.
66 citations
,
July 2015 in “Journal of Molecular Biology” This review discusses how macro-environmental factors such as intradermal adipose tissue and sex hormones influence hair and feather stem cell niches, suggesting environmental targets for regenerative medicine, but reports no new clinical results.
48 citations
,
June 2020 in “Current Rheumatology Reports” This review explores the diverse roles and heterogeneity of fibroblasts across different organs, highlighting their potential involvement in both normal tissue functioning and fibrotic diseases, but reports no new experimental results.
36 citations
,
November 2019 in “Molecular biology and evolution” This study suggests that the keratins found in reptile and bird skin appendages evolved independently from mammalian hair keratins, highlighting convergent evolution in these species.
26 citations
,
May 2014 in “BioEssays” This review discusses how neuroendocrine pathways influence keratin regulation in human skin and hair follicles and suggests these pathways as potential targets for new treatments of skin disorders, but reports no clinical results.
18 citations
,
February 2023 in “PLoS ONE” This study developed a triple drug delivery system using nanoparticles loaded with 5-fluorouracil, curcumin, and piperine to target breast tumors, demonstrating notable in vitro cytotoxicity and anti-metastatic potential in 3D tumor spheroids which suggests its promise for further preclinical evaluation.
6 citations
,
June 2012 in “Physiology” This review discusses current airway regeneration research efforts and reports no new experimental results, highlighting the need for clinical interventions to enhance airway repair.
4 citations
,
January 2021 in “Dermatologic Therapy” This review highlights current and future AI applications in hair restoration and diagnosis of hair disorders, including automated systems for hair detection and self-diagnosis, emphasizing the need for experts to understand their benefits and limitations.
1 citations
,
April 2016 in “CRC Press eBooks” Skin aging reflects overall body aging and can indicate internal health conditions.
1 citations
,
January 2013 in “Journal of Investigative Dermatology” The document concludes that stem cells and their environments are crucial for skin and hair health and have potential for medical treatments.
July 2026 in “International Journal of Advanced Research in Science Communication and Technology” In this study, the BaldGraphFormer framework, integrating visual and clinical data, outperformed unimodal baselines in early-stage androgenetic alopecia detection, achieving an F1-score of 97.62% and macro-average AUC of 0.992, suggesting its potential to support dermatological decision-making and early intervention.
June 2026 in “International Journal of Drug Delivery Technology” In this study, researchers optimized fast-dissolving tablets of nifedipine using a systematic approach, resulting in formulations that demonstrated rapid disintegration, enhanced dissolution profiles, and improved solubility, potentially improving oral delivery for patients requiring poorly soluble antihypertensive medication.
June 2026 in “arXiv (Cornell University)” This study investigated the dynamic mechanical properties of fluid-immersed elastic hair beds under oscillatory shear flows, revealing a nonlinear response influenced by driving frequency and amplitude, which impacts mechanosensory signaling stability in biological processes like vasodilation and ciliary remodeling.
November 2025 in “Nature Communications” This study used a 3D live imaging system to map cell dynamics in human hair follicles, revealing patterns of cell movement and division that help explain hair fiber extrusion during hair growth.
This study revealed that during avian skin development, complex tissue architecture results from specific cellular flows and mechanical processes that guide feather bud protrusion and elongation, with distinct differences noted in scale development, where rigidity restricts such transformations.
April 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” In this study, researchers found that in growing skin tissue, epidermal wound healing occurs at the expense of normal skin development, as it impairs hair follicle growth and does not activate tissue morphogenesis genes.
1 citations
,
January 2016 in “International journal of research in ayurveda and pharmacy” This study found that a herbal formulation optimized with specific concentrations of plant extracts showed promising antifungal activity against Malassezia furfur.
196 citations
,
March 2016 in “Nature Communications” In this study, researchers identified 18 genetic associations with scalp and facial hair traits in Latin Americans, including novel loci for hair greying and balding, with implications for understanding hair evolution.
150 citations
,
April 1999 in “Dermatologic Clinics” This article reviews the biological and physical principles of laser hair removal and reports that current laser systems do not consistently achieve permanent hair follicle destruction across treated areas.
5 citations
,
May 2023 in “European Journal of Human Genetics” This study found that mutations in the TULP3 gene are associated with progressive degeneration of the liver, kidney, and heart in adults, highlighting the importance of early detection and management.
April 2021 in “Journal of Investigative Dermatology” This study found that skin bacteria promote regeneration in wound-induced hair follicle neogenesis, suggesting a role for IL-1β signaling and challenging the belief that infection inhibits healing.