237 citations,
February 2016 in “Science Translational Medicine” The timing of when the gene Bmal1 is active affects aging and survival, with its absence during development, not adulthood, leading to premature aging.
218 citations,
October 2013 in “Proceedings of the National Academy of Sciences of the United States of America” Mice lacking the PPARγ gene in their fat cells had almost no fat tissue, severe metabolic problems, and abnormal development of other fat-related tissues.
215 citations,
March 2018 in “Archives of Toxicology” Tiny pollution particles called PM2.5 can harm skin cells by causing stress, damage to cell parts, and cell death.
213 citations,
December 2020 in “Annals of internal medicine” Many COVID-19 patients still have symptoms like fatigue and loss of taste or smell a month after diagnosis.
54 citations,
April 2010 in “Baillière's best practice and research in clinical endocrinology and metabolism/Baillière's best practice & research. Clinical endocrinology & metabolism” Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.
54 citations,
December 2007 in “Best Practice & Research Clinical Endocrinology & Metabolism” Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.
52 citations,
January 2005 in “International journal of experimental pathology” Melatonin may reduce skin damage caused by X-rays in rats.
49 citations,
December 1997 in “Urology” Tamoxifen effectively treats gynecomastia without causing impotence.
48 citations,
July 2002 in “Journal of Cutaneous Medicine and Surgery” Skin problems are common and important signs of eating disorders and treating the eating disorder can improve these skin conditions.
33 citations,
April 2002 in “Journal of Cutaneous Medicine and Surgery” Eating disorders can cause skin problems that need treating the underlying condition for better health.
33 citations,
January 1997 in “Endocrinology” Testosterone can slow down hair growth when combined with certain cells from bald scalps, and this effect can be blocked by an androgen receptor blocker.
30 citations,
February 2018 in “Journal of Pharmacy and Pharmacology” Hedychium spicatum has medicinal properties but needs more research for scientific validation and use.
24 citations,
July 2018 in “Drug Design Development and Therapy” NTF gel improves finasteride delivery for hair loss treatment, reducing side effects.
24 citations,
September 2001 in “Journal of The American Academy of Dermatology” Women's ovarian hormones and adrenal androgens change throughout life, affecting hair loss and health.
23 citations,
March 2019 in “Environmental Chemistry Letters” Cyclodextrins improve how steroid drugs work and are used in marketed medications and environmental applications.
22 citations,
December 2016 in “PloS one” A specific protein in chicken embryos links early skin layers to feather development.
20 citations,
November 2012 in “Journal der Deutschen Dermatologischen Gesellschaft” Hair diseases can have psychological effects and should be treated with a combination of psychosomatic care, therapy, and medication.
20 citations,
April 2011 in “Dermatologic Surgery” Laser therapy helped new hair grow in scarred skin for three patients.
20 citations,
February 2002 in “Expert Opinion on Therapeutic Patents” New research is needed to create better drugs that block the enzyme responsible for conditions like male baldness and prostate enlargement.
17 citations,
August 2001 in “Australasian journal of dermatology” A woman's liver problems improved after she stopped taking spironolactone.
16 citations,
September 2008 in “American Journal of Orthodontics and Dentofacial Orthopedics” Wearing orthodontic headgear can cause reversible hair loss if detected early.
15 citations,
October 2012 in “Journal of circadian rhythms” RNA from horse hair follicles can track circadian rhythms non-invasively.
15 citations,
June 1995 in “The American Journal of the Medical Sciences” Finasteride caused enlarged breast tissue in a 62-year-old man.
12 citations,
October 1954 in “Textile Research Journal” Hair absorbs alkali bromide salts and water, affecting its structure, with absorption decreasing at higher temperatures.
11 citations,
May 2019 in “BioMed Research International” Hair transplantation effectively treats scalp scars with high success and patient satisfaction.
10 citations,
August 2015 in “Journal of Cosmetic Dermatology” Successful eyebrow restoration can be done using careful hair transplant techniques and choosing the right patients.
10 citations,
November 2000 in “Aesthetic Surgery Journal” Secondary aesthetic surgeries for gender reassignment are generally satisfying and advance overall aesthetic surgery techniques, but psychological support is important.
10 citations,
December 1997 in “Plastic and Reconstructive Surgery” Hair restoration surgery has improved with better techniques for natural looks and managing patient expectations, but it remains labor-intensive and requires careful consideration of potential complications.
9 citations,
January 2011 in “Skin Research and Technology” The new automatic tool accurately measures hair thickness and is reliable.
8 citations,
February 2017 in “Archives of Dermatological Research” Intense pulsed light treatment effectively reduces underarm hair by making hair follicles smaller and extending their resting phase.