3 citations
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February 2021 in “JAMA Dermatology” Masculinizing hormone therapy increases the risk of hair loss in transgender and gender-diverse patients.
3 citations
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February 2025 in “Journal of the American Academy of Dermatology” This study highlights how sex steroids affect hair growth, reporting that testosterone used in masculinizing hormone therapy can lead to androgenetic alopecia in transgender individuals, while feminizing hormone therapy with estradiol and antiandrogens can reduce hirsutism.
October 2024 in “Journal of the Endocrine Society” This study found that feminizing hormone therapy increased GFR in transgender individuals assigned male at birth, suggesting an effect of sex hormones on kidney hemodynamics, while masculinizing therapy showed a slight, nonsignificant decrease in GFR.
May 2023 in “Journal of drugs in dermatology” Most transgender patients getting laser hair removal before gender-affirming surgery are already on hormone therapy, which might affect the hair removal process.
April 2021 in “Journal of Investigative Dermatology” This study found that transgender patients on masculinizing hormone therapy had a higher likelihood of developing acne compared to cisgender women, and were more likely to experience AGA compared to cisgender women.
34 citations
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April 2023 in “Climacteric” This review discusses the long-term effects of gender affirming hormone therapy and reports no new clinical findings, recommending a shared decision-making approach to balance benefits and risks for transgender individuals.
7 citations
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May 2019 in “British Journal of Dermatology” In this study, testosterone use in gender-minority patients was associated with significantly worse androgenetic alopecia severity scores, while feminizing hormone therapy did not significantly change hair loss severity.
4 citations
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July 2021 in “Dermatology and therapy” This review examines changes in hair physiology and treatment options for transgender patients on hormonal therapy but reports no new clinical findings, offering treatment recommendations based on the authors' experiences.
1 citations
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April 2022 in “Emergency Medicine Australasia” This article discusses the negative experiences transgender individuals often encounter in emergency healthcare settings and emphasizes the importance of gender-affirming practices, but it reports no new clinical results.
February 2023 in “Journal of The American Academy of Dermatology” This study found that transgender and gender diverse patients on masculinizing hormone therapy had 2.5 times the rate of androgenetic alopecia compared to cisgender women.
1 citations
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April 2024 in “Archives of disease in childhood” This systematic review found that among children and adolescents referred to specialist gender services, 36% received puberty suppression and 51% received masculinising or feminising hormones, but comprehensive data on psychological care and treatment pathways were lacking.
5 citations
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September 2021 in “Southern African Journal of Hiv Medicine” The guideline provides healthcare professionals in South Africa with instructions for comprehensive, multidisciplinary gender-affirming care, including HIV prevention and treatment for transgender and gender diverse individuals.
15 citations
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February 2019 in “Internal Medicine Journal” This study found that experienced Australian prescribers of hormone therapy for transgender adults often follow international guidelines but highlight the need for better training and specific local guidelines.
June 2023 in “Clinical and Experimental Dermatology” This systematic review reported that gender-affirming hormone therapy may lead to changes in hair growth patterns, with differing effects for transgender men and women, potentially impacting quality of life.
4 citations
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January 2022 in “Journal of Menopausal Medicine” This review discusses gender-affirming hormone therapies in South Korea, detailing the available treatment regimens and associated side effects, but reports no new clinical findings.
5 citations
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March 2019 in “Facial Plastic Surgery Clinics of North America” In this article, the authors reviewed essential terminology and recommendations for creating a welcoming healthcare environment for transgender patients and providing gender-affirming therapy, emphasizing the unique health needs and disparities faced by this population.
November 2023 in “Australasian journal of dermatology” This review highlights the dermatological needs of transgender and gender diverse individuals in Australia, emphasizing the role of dermatologists in managing skin and hair conditions related to gender affirmation and hormone therapy.
2 citations
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December 2020 in “JAMA Dermatology” In this study, the incidence of androgenic alopecia among transgender patients increased after starting masculinizing hormone therapy, with the highest incidence observed in the fourth year of treatment.
research Hair
May 2024 in “Australasian Journal of Dermatology” This study assessed the psychosocial impact and disease burden of alopecia areata among adolescents and adults in Australia, finding substantial impacts on physical, emotional, and quality of life overall, with greater disease burden in patients experiencing more extensive hair loss.
6 citations
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April 2019 in “Endocrinology and Metabolism Clinics of North America” This study observed that testosterone therapy in transgender men enhances both physical and mental health, is safe in the short and middle term with proper follow-up, and highlights the need for endocrinologists to provide gender-affirming care despite its limited presence in medical education.
146 citations
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December 2016 in “Translational Andrology and Urology” This review discusses the creation of transgender-specific guidelines by WPATH and the Endocrine Society, based mostly on clinical experience, and reports no new results.
21 citations
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November 2014 in “Journal of Endocrinological Investigation” This review discusses cross-sex hormone therapy for managing gender dysphoria in transsexual individuals and reports no new clinical results; it highlights the need for education and culturally sensitive training for healthcare professionals.
28 citations
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October 2018 in “Clinical Obstetrics and Gynecology” This study suggests that gender-affirming testosterone therapy in transgender men is generally safe and effective with adequate screening and monitoring, although high-quality long-term studies are lacking.
20 citations
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January 2003 in “Treatments in Endocrinology” Testosterone therapy can help improve mood, sexual function, and bone health in women with low androgen levels, but more research is needed to establish safe and effective guidelines.
July 2023 in “The Journal of Clinical Endocrinology and Metabolism” This narrative review suggests that, after at least two years of gender-affirming hormone therapy, nonathletic transgender individuals tend to have physical performance levels similar to cisgender individuals, though more controlled research is necessary, particularly among trans athletes.
17 citations
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January 2015 in “MedChemComm” New treatments for prostate cancer are less toxic and show promise, but more research is needed to enhance their effectiveness and reduce side effects.
9 citations
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May 2024 in “Journal of Clinical & Translational Endocrinology” This review examines existing evidence on the efficacy and safety of gender affirming hormone therapy in relation to Gender Affirmation Surgery, but reports no new clinical results.
1 citations
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November 2023 in “Medicina” This narrative review emphasizes the significant improvements in mental well-being linked to gender-affirming treatments while highlighting the need for ongoing research into hormone therapy's long-term effects and its impact on transgender individuals' reproductive health.
January 2025 in “ARC Journal of Dermatology” This study discusses the importance of careful dermatological care for transgender youth receiving hormonal therapies, cautioning that acne treatments can interfere with hormone replacement therapy and emphasizing the need for a collaborative interdisciplinary approach to support both acne management and overall well-being.
January 2021 in “Open MIND” This scoping review aims to explore the impact of hormone therapy on the laboratory profiles of transgender people, identify evidence, and highlight literature gaps, particularly in developing countries.