165 citations
,
August 2013 in “Lasers in Surgery and Medicine” This review discusses the potential mechanisms and evidence supporting low-level laser therapy for stimulating hair growth in men and women, while noting its safety and effectiveness but needing further study on specific parameters.
14 citations
,
July 1994 in “Journal of Dermatological Science” In this study, transgenic mice expressing a mutant K6 gene developed progressive scarring alopecia and keratosis, suggesting they may model a new keratin disorder.
5 citations
,
May 2021 in “EMBO journal” This review discusses the role of polarity signaling in coordinating tissue mechanics, micro-environmental functions, and cell fate decisions, but it reports no new results, highlighting the need for further study in mammalian models.
June 2025 in “Frontiers in Bioengineering and Biotechnology” In this study, the researchers observed that a recombinant human collagen complex with nicotinamide promoted hair growth in rat models, increased hair follicle stem cell survival, and enhanced key protein expression, suggesting potential benefits for hair health and loss prevention.
February 2025 in “Science Advances” This study demonstrates that Wnt signaling plays a crucial mechanoregulatory role in skin regeneration by influencing cellular responses to substrate rigidity, which promotes hair follicle regeneration in the wound-induced hair neogenesis model.
October 2025 in “Pakistan journal of urology.” This supplementary issue of the Pakistan Journal of Urology contains diverse studies spanning organ donation's significance, surgical techniques, and the comparison of treatments in urology, but it doesn't provide specific research results or detailed findings.
36 citations
,
November 2019 in “Molecular biology and evolution” This study suggests that the keratins found in reptile and bird skin appendages evolved independently from mammalian hair keratins, highlighting convergent evolution in these species.
196 citations
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March 2016 in “Nature Communications” In this study, researchers identified 18 genetic associations with scalp and facial hair traits in Latin Americans, including novel loci for hair greying and balding, with implications for understanding hair evolution.
76 citations
,
July 2019 in “Cellular and Molecular Life Sciences” This article reviews the role of stem cells in tissue development, tumor formation, and organoid generation, and highlights the potential of epigenetic regulation in advancing regenerative medicine and cancer treatment, without presenting new experimental results.
45 citations
,
March 2020 in “ACS Applied Materials & Interfaces” In this study, researchers created a novel fibrous membrane inspired by ancient Chinese medicine that effectively promotes hair follicle regeneration and wound healing in deep burn injuries by releasing quercetin, copper, and silicon ions.
21 citations
,
November 2022 in “Frontiers in immunology” This article reviews sebaceous immunobiology and highlights the complex role of sebaceous glands and sebocytes in skin barrier function and inflammation, particularly in acne pathogenesis, but reports no new results.
19 citations
,
January 2009 in “International review of cell and molecular biology” This review explains the mechanical composition and molecular interactions that determine hair's mechanical properties, without providing any new experimental findings.
15 citations
,
June 2015 in “Lasers in Medical Science” This study found that low-level laser therapy with an 830-nm wavelength most significantly stimulated hair growth in rats, compared to other wavelengths tested.
6 citations
,
October 2018 in “PLoS ONE” This study found that chronic stress may inhibit hair follicle growth and melanogenesis in mice through modulation of the central HPA axis, with C57BL/6 mice appearing most sensitive to these effects.
September 2025 in “Experimental & Molecular Medicine” This study observed that the small molecules KY19382 and KY19334 inhibited cancerous traits in human cutaneous squamous cell carcinoma cells by suppressing the Wnt/β-catenin pathway, indicating their potential as treatments for cancers involving CDK1 overexpression and diseases related to CXXC5 accumulation.
This research found that keratin hydrogels derived from human hair may support cell viability and proliferation, indicating potential as 2D and 3D soft tissue culture scaffolds.
January 2019 in “Springer eBooks” This chapter discusses procedural therapies like platelet-rich plasma and low-level light therapy for androgenetic alopecia, but reports no new clinical findings.
50 citations
,
September 2011 in “Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids” This review examines the role of retinoic acid synthesis in hair follicles and sebaceous glands, focusing on its localization and function during normal and disease states, but reports no new results.
June 2026 in “Bulletin of Mathematical Biology” This study reported that in male subjects with androgenetic alopecia, there is greater uncertainty in hair growth duration, with regulatory factors in the dermal papilla significantly affecting outcomes.
April 2026 in “Mathematics” This study used a probabilistic framework to show that platelet-rich plasma preparation results in significant variability in platelet dose due to factors like injected volume and concentration factor.
31 citations
,
February 2007 in “Journal of Structural Biology” Oxidation changes the structure of hair protein filaments, causing them to compact and rearrange.
98 citations
,
December 2015 in “The Journal of Cell Biology” In this study, researchers found that the absence of type I or type II keratins in mice leads to severe skin barrier defects, highlighting keratins' crucial role in epidermal structure and function.
June 2026 in “Nature Communications” This study found that in stretch-mediated tissue expansion, fibroblasts adopt an embryonic-like, low-collagen state that enhances epidermal stem cell renewal, supporting coordinated skin expansion crucial for reconstructive surgeries.
February 2026 in “Pharmaceuticals” This study introduced the KRDQN predictive framework, which outperformed existing methods in predicting adverse drug reactions and provided interpretable insights into drug mechanisms, aiding pharmacovigilance and clinical decision-making.
119 citations
,
February 2009 in “Neuroscience & Biobehavioral Reviews” This review discusses the psychological and neurobiological aspects of trichotillomania and reports no new results, emphasizing the need for further research on its treatment and neural mechanisms.
56 citations
,
September 2010 in “Veterinary pathology” This study found that certain C57BL/6 mouse substrains have a genetic vulnerability to skin lesions resembling central centrifugal cicatrical alopecia in humans, potentially worsened by high vitamin A levels.
40 citations
,
November 2021 in “International Journal of Molecular Sciences” This review highlights the role of keratin mutations in epidermolysis bullosa simplex and the resulting chronic inflammation, but it presents no new experimental findings.
1 citations
,
September 2025 in “Physiologia” This study found that systemic ovalbumin–aluminum sensitization followed by cutaneous challenge in mice induced thermal hyperalgesia, increased spinal cord gliosis, and sprouting of nociceptive fibers, along with elevated mast cell and nerve profile densities in the skin compared to controls.
4 citations
,
December 2023 in “PubMed” This review discusses dietary interventions as a modifiable factor in managing hidradenitis suppurativa and reports no new clinical results, emphasizing the need for informed lifestyle choices.
30 citations
,
July 2010 in “Experimental Dermatology” This article reviews the role of polyamines in hair follicle growth and discusses potential therapeutic applications but provides no new clinical results.