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This review article summarizes findings that suggest natural products may help treat skin inflammation related to abnormal hormone secretion by the adrenal gland, as they can inhibit inflammation pathways and promote wound healing.

In this study, miR-221 was identified as a key factor in androgenetic alopecia pathogenesis due to its role in suppressing hair growth by interacting with androgen receptors and affecting related pathways.

This study found that D-peptide crosslinked MAP hydrogels accelerate skin regeneration and promote adaptive immunity, despite faster scaffold degradation in vivo.

In this review, researchers explored the multifaceted role of NF-κB signaling in various biological processes and diseases, including its interactions with other pathways, and discussed possible therapeutic approaches targeting this pathway for treating conditions like cancer, autoimmune disorders, and COVID-19.

This study found that treating cashmere goat kids with melatonin significantly increased secondary hair follicle density, improving cashmere quality and yield, likely through mechanisms involving the MAPK signaling pathway.

This study identified proteins involved in hair follicle formation in cashmere goat embryos, highlighting potential signaling factors that may drive hair follicle initiation and cashmere growth.

This computational study developed a regulatory model linking key genes and miRNAs to cardiac senescence, validated by connecting 94% of these elements to existing cardiac aging research.

This review synthesizes research on hederagenin's anticancer and anti-inflammatory potential, emphasizing chemical modifications to enhance its bioactivity, but reports no new experimental findings.

This study found that Centipeda minima and brevilin A significantly reduced oxidative stress and inflammation in human dermal fibroblasts, suggesting their potential to protect against skin aging and inflammation.

This study identified 674 differentially expressed proteins in the skin tissues of male and female Chinese merino sheep, suggesting gender-specific molecular mechanisms that may affect wool traits.

This study identified differentially expressed microRNAs between back and belly skin in Rex rabbits, highlighting their potential roles in skin development processes.

In this study, OEA was found to significantly enhance sebaceous lipogenesis and potentially reduce inflammation in human sebocytes, suggesting it as a promising candidate for treating skin dryness.

In this study, exposure to m-Aminophenol in human keratinocytes altered the expression of thousands of genes involved in inflammation and stress responses, suggesting potential biomarkers for MAP-induced skin toxicity.

This study indicates that MAGE-11 modulates androgen receptor transcriptional activity through F-box interactions, independent of the activation function 2 pathway, revealing a novel mechanism for androgen receptor regulation.

This research observed that diabetes impairs wound healing in mice by disrupting key mechanotransduction pathways in fibroblasts, which are crucial for the healing process. The study also suggests transcriptomic changes could inform future diabetic wound repair therapies.

In this study, researchers used transcriptome sequencing to identify 1543 differentially expressed genes between cashmere and normal goats, implicating several signaling pathways and key regulators in the distinct gene expression profiles linked to cashmere fiber production, which advances understanding of cashmere goat genetics.

In this study, researchers identified 19 genetic risk loci and highlighted 16 candidate causal genes, including immune-related ones, associated with polycystic ovary syndrome, emphasizing the role of specific immune cells like T cells and NK cells in its pathogenesis.

In this preclinical study, PA-011 derived from Periplaneta americana showed significant hair regrowth effects in androgenetic alopecia mouse models by inhibiting inflammation and oxidative stress, activating hair follicle stem cell proliferation, and normalizing skin microbiota, suggesting promise as an AGA treatment.

This study found that miRNA-24 downregulates the KLF6 gene, influencing coat color by affecting melanogenesis pathways in Cashmere goats, and that miRNA-24 inhibition increased melanin content in mice.

In this study, researchers identified significant differences in lipid composition between grey and black hair follicles in women with type 2 diabetes and healthy controls, suggesting these lipids may contribute to the production of grey hair and may offer targets for anti-grey-hair treatments.

In this study, researchers identified thousands of mRNA, lncRNA, circRNA, and miRNA transcripts involved in different hair follicle stages of Rex rabbits and highlighted significant gene expression changes and pathway enrichments, providing insights into the regulatory mechanisms of hair development in these animals.

In this study, chick embryo extract enhanced neuronal differentiation and trophic factor expression in rat hair follicle stem cells, suggesting potential improvements for stem cell therapies in neurodegenerative diseases.

Ganoderma lucidum extract may help treat stress-related hair loss.

This review discusses the genetic pathways involved in melanoma and suggests that targeting these pathways with pharmacological inhibitors may provide a new therapeutic approach, though clinical results have been disappointing so far.

This study found that Rex rabbits had significantly shorter fibre length and thinner fur compared to New Zealand White rabbits, and identified a gene-metabolite network that may influence fur quality and development.

This study found that administering tolerogenic dendritic cell-conditioned medium to dihydrotestosterone-treated mice promoted hair regrowth by modulating the follicular microenvironment, reducing pro-inflammatory cytokines, and activating key signaling pathways, highlighting its potential as a treatment for androgenetic alopecia.

This review highlights the potential of exosome-based therapies for androgenetic alopecia by modulating key signaling pathways in hair follicles, suggesting a promising treatment option that requires further research to validate long-term safety and efficacy.

This review summarizes the potential of exosome-based therapies as a promising treatment for androgenetic alopecia, emphasizing their role in modulating key signaling pathways, but highlights the need for further evidence to confirm their efficacy and safety.

This study highlights the potential of stem cell-derived extracellular vesicles to treat UV-induced skin damage by modulating key signaling pathways, though challenges like EV composition variability and skin barrier penetration remain, underscoring the need for further research into optimized delivery methods for effective therapies.

Tanshinone Capsule may help regrow hair by boosting specific cell signals.