research New Progesterone Esters as 5α-Reductase Inhibitors
Some new progesterone derivatives are better at blocking testosterone conversion than a common drug.
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research Recent Advances in the Chemistry and Pharmacological Activity of New Steroidal Antiandrogens and 5α-Reductase Inhibitors
New compounds show promise for treating hair loss, enlarged prostate, and prostate cancer, with some being more effective and having different side effects than current treatments.
research Molecular Interactions of New Pregnenedione Derivatives
The new progesterone derivatives effectively inhibit 5α-reductase and bind to the androgen receptor.
research Class III Peroxidases PRX01, PRX44, and PRX73 Control Root Hair Growth in Arabidopsis Thaliana
PRX01, PRX44, and PRX73 are essential for root hair growth in Arabidopsis thaliana.
research The Effect of Finasteride and Dutasteride on the Synthesis of Neurosteroids by Glioblastoma Cells
Finasteride and dutasteride reduce neurosteroid production, possibly helping treat glioblastoma.
research An Unusual Case Report of Rapunzel Syndrome Trichobezoar in a 3-Year-Old Boy
A 3-year-old boy had a rare hairball condition usually seen in teenage girls.
research Androgenic and Anti-Androgenic Effects of Progesterone Derivatives with Different Halogens as Substituents at the C-6 Position
Different halogens on progesterone derivatives can either block or mimic male hormone effects, depending on their type and amount.
research Synthesis and Pharmacological Evaluation of New 16-Methyl Pregnane Derivatives
New pregnane derivatives were more effective than finasteride at inhibiting a key enzyme for male pattern baldness.
research Patients With Vitiligo Present Fewer Cardiovascular Risk Factors: Results From a Case-Control Study
People with vitiligo may have a lower risk of heart disease.
research Expression of the SCUBE3 Epidermal Growth Factor-Related Gene During Early Embryonic Development in the Mouse
Scube3 gene affects mouse embryo growth in multiple areas, but needs more research.
research Biological Activity of Novel Progesterone Derivatives Having Bulky Ester Side Chains at C-3
The more lipophilic the progesterone derivative, the better it binds to androgen receptors and has antiandrogenic effects.
research Ayurveda-Based Botanicals as Therapeutic Adjuvants in Paclitaxel-Induced Myelosuppression
Asparagus racemosus and Withania somnifera can help reduce side effects of a cancer drug.
research Solid Lipid Nanoparticles: A Promising Technology for Delivery of Poorly Water-Soluble Drugs
Solid lipid nanoparticles can improve how well drugs that don't dissolve in water work and are safe.
research Growth in Turface Clay Permits Root Hair Phenotyping Along the Entire Crown Root in Cereal Crops and Demonstrates That Root Hair Growth Can Extend Well Beyond the Root Hair Zone
Root hairs in cereal crops can grow beyond the usual zone, and using Turface® clay helps study this.
research Dermoscopy Findings in Female Androgenetic Alopecia
Dermoscopy effectively diagnoses and evaluates female hair loss treatment.
research Comparative Study Between Mesotherapy and Topical 5% Minoxidil by Dermoscopic Evaluation for Androgenic Alopecia in Males: A Randomized Controlled Trial
Mesotherapy is not significantly better than minoxidil for treating male hair loss.
research Bone Mineral Density Is Unaltered in Women with Polycystic Ovary Syndrome
Women with PCOS have similar bone density to healthy women, but those who are obese have higher bone density at some body sites.
research Recent Advances in Drug Design and Drug Discovery for Androgen-Dependent Diseases
New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.
research Role of Caffeine in the Management of Androgenetic Alopecia
Caffeine may help hair growth in hereditary hair loss.
research Annular Alopecia Areata: Report of Two Cases
Two people had unusual ring-shaped hair loss due to an autoimmune disorder.
research Atrichia With Papular Lesions
Accurate diagnosis of APL is crucial to avoid unnecessary treatments.
research Persistent Post COVID-19 Symptoms and Functional Status After 12-14 Weeks of Recovery, Tamil Nadu, India, 2021
One in four people still had symptoms like weight loss, hair loss, and fatigue 12-14 weeks after recovering from COVID-19.
research Premature Graying of Hair: Risk Factors, Co-Morbid Conditions, Pharmacotherapy and Reversal—A Systematic Review and Meta-Analysis
Premature graying of hair is linked to various health issues and can sometimes be reversed by treating underlying conditions.
research Adverse Effects with Finasteride 5 mg/Day for Patterned Hair Loss in Premenopausal Women
Taking 5 mg/day finasteride can cause side effects in women with hair loss, but these are usually mild and fade over time, making the treatment beneficial in the long run.
research Corrective Hyaluronic Acid Fillers and Combination Cosmetic Treatments for Facial Cutaneous Defects Due to Autoimmune Connective Tissue Diseases: A Retrospective Review
Hyaluronic acid fillers and combination treatments significantly improve facial defects from autoimmune diseases and are well-tolerated.
research Diffuse Scalp Hair Loss Due to Levothyroxine Overdose
Too much levothyroxine can cause hair loss in infants.
research New Aromatic Esters of Progesterone as Antiandrogens
New progesterone-based compounds can block male hormones.
research RP HPLC Method for the Determination of Finasteride and Tamsulosin in Bulk and Pharmaceutical Formulations
research Relative Binding Affinity of Novel Steroids to Androgen Receptors in Hamster Prostate
New steroids were effective in blocking male hormone receptors in hamster prostates.
research ELL Facilitates RNA Polymerase II-Mediated Transcription of Human Epidermal Proliferation Genes
ELL is crucial for gene transcription related to skin cell growth.