August 2020 in “Research Square (Research Square)” In this study, transplantation of rat hair follicle stem cells was associated with reduced infarct volume and enhanced neurological recovery after ischaemic stroke, suggesting therapeutic potential for further clinical development.
May 2020 in “Research Square (Research Square)” This study found that hair follicle stem cells, when transplanted in a rat model of ischaemic stroke, migrated to affected areas, expressed neuron-specific markers, and reduced infarct volume, suggesting potential therapeutic benefits.
April 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” The researchers reported that disrupting the RPGRIP1L gene in mice impaired desmosome function, causing skin blistering, and their findings suggest that PKCβII inhibition could help treat pemphigus.
April 2016 in “Journal of Investigative Dermatology” Iron deficiency causes hair loss by affecting hair differentiation and cycling.
This study identified a 14,883 bp genomic deletion affecting the Plcd1 and Vill genes as likely responsible for the abnormal phenotype observed in snthr-1Bao mice.
February 2023 in “Frontiers in Pharmacology” This study found that the water extract of Cacumen Platycladi promotes hair growth and follicle development in mice, possibly by influencing dermal papilla cells through the Akt/GSK3β/β-Catenin signaling pathway.
February 2023 in “Journal of Plant Physiology” In this study, overexpressing the cotton gene GhGT-3b_A04 in Arabidopsis thaliana enhanced resistance to Verticillium wilt but also inhibited rosette leaf growth.
January 2023 in “Frontiers in Medicine”
December 2022 in “Acta Biomaterialia” Corrections were made to a previous work on 3D printing a gel-alginate mix for creating hair follicles, but the main finding - that this method can help grow hair - remains the same.
November 2022 in “Frontiers in Medicine” This study found no direct association between androgenetic alopecia and metabolic syndrome in the Chinese population, though AGA was closely linked with higher systolic blood pressure in men.
January 2022 in “Social Science Research Network” This study found that in androgenetic alopecia, the androgen receptor directly increases miR-221 transcription, which suppresses hair growth by targeting IGF-1 and inactivating specific signaling pathways.
May 2017 in “Chinese Journal of Dermatology” This study reported that alopecia can moderately impact patients' quality of life and is linked to a depressive tendency, with frequent medical visits and higher quality of life impairment as risk factors.
133 citations
,
January 2009 in “Nature” This study identified gene expression patterns in a mouse model that may influence tumor susceptibility and tissue functions related to inflammation and cell proliferation, highlighting Lgr5 and the vitamin D receptor as key regulators.
72 citations
,
August 2014 in “Genome Biology and Evolution” This study found that the differential expression of α- and β-keratin genes in feathers may explain their morphological and structural diversity, highlighting the chicken as a model for studying keratin-related diseases.
45 citations
,
October 2015 in “BMC Genomics” This study identified morphotype-specific gene expression patterns in feathers, enhancing understanding of the molecular and cellular processes involved in feather development and diversification.
39 citations
,
April 2020 in “IntechOpen eBooks” The authors describe drug repurposing as a promising strategy for finding new uses for existing drugs, noting it is efficient, cost-effective, and poses lower risks than traditional drug discovery processes, potentially aiding in the treatment of rare and difficult-to-treat diseases.
36 citations
,
April 2013 in “Cell and Tissue Research” Bone-marrow and epidermal stem cells help heal wounds differently, with bone-marrow cells aiding in blood vessel formation and epidermal cells in hair growth.
27 citations
,
June 2019 in “Aesthetic Plastic Surgery” Platelet-Rich Plasma (PRP) treatment may increase hair growth for genetic hair loss, but more research is needed to confirm this.
7 citations
,
August 2025 in “Journal of Nanobiotechnology” This review highlights the potential of microneedles and nanomedicine in advancing tissue regeneration, emphasizing their innovative, localized, and minimally invasive approaches as promising solutions to current challenges in treating chronic wounds and degenerative diseases.
7 citations
,
May 2010 in “Drug Delivery” This study found that retinoic acid pre-treatment enhanced the efficiency of gene transfer into mouse skin for potential therapeutic applications.
2 citations
,
July 2022 in “Frontiers in Medicine” This review discusses the current understanding of frontal fibrosing alopecia's pathogenesis, highlighting genetic susceptibility, immune response involvement, and possible links to steroid hormones, but reports no new clinical results.
1 citations
,
August 2022 in “Frontiers in Physiology” This study suggests that finasteride may help alleviate high-fat diet-induced kidney damage in mice by reducing TMAO synthesis and regulating gut microbiota.
August 2026 in “Stem Cell Research & Therapy” This review found that while MSC and EV-based therapies could potentially improve skin and hair rejuvenation, their clinical efficacy is limited by inconsistent study designs and a lack of standardization.
April 2026 in “Frontiers in Pharmacology” This review systematically evaluates Erzhi Pill's formulation, therapeutic potential, and challenges, exploring its traditional applications and modern prospects for developing integrated quality control and precise medical strategies.
January 2020 in “Advanced ultrasound in diagnosis and therapy” This case report highlights a misdiagnosis of an epidermoid cyst as a dermoid cyst using ultrasound, suggesting that specific ultrasound features can improve diagnostic accuracy for skin lesions.
31 citations
,
May 2019 in “Nature communications” This study found that Blimp1+ cells from mice can generate sebaceous gland organoids in vitro, which mimic natural gland traits and may aid in studying acne vulgaris.
13 citations
,
May 2019 in “Cancer Prevention Research” This study found that a three-month regimen of leucoselect phytosome, a grape seed extract complex, was well tolerated and significantly reduced bronchial proliferation markers in heavy active and former smokers.
October 2017 in “The American Journal of Gastroenterology” This case report details a 71-year-old man diagnosed with Cronkhite-Canada Syndrome, highlighting the importance of early diagnosis and endoscopic evaluation due to the disease's progressive nature and significant mortality risk.
This study investigates whether adding 30% supramolecular salicylic acid to conventional treatment for mild to moderate acne vulgaris is safe and effective, though specific results are not reported in the abstract.
11 citations
,
July 2022 in “Frontiers in immunology” This study reports that the global age-standardized incidence and disability-adjusted life-year rates of alopecia areata decreased from 1990 to 2019, with the highest increases in incidence seen in some low SDI regions and countries like Kuwait and South Sudan.