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The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

Skin grafts are effective for chronic leg ulcers, especially autologous split-thickness grafts for venous ulcers, but more data is needed for diabetic ulcers.

Hair's internal fibers are arranged in a pattern that doesn't let much water in, and treatments like oils and heat change how much water hair can absorb.

The Wnt signaling pathway is not a major factor in the development of keratoacanthoma, a type of skin tumor.

The document concludes that there are various causes and treatments for hair loss, with hair transplantation being a notable option.

Hair follicle stem cells are crucial for touch sensation and proper nerve structure in mice.

PCOS lowers quality of life, causing issues like obesity, infertility, and menstrual problems.

The document concludes that while some organisms can regenerate body parts, mammals generally cannot, and cancer progression is complex, involving mutations rather than a strict stem cell hierarchy.

AFM can diagnose hair disorders by revealing detailed hair surface changes.

Children with cancer had slightly more unusual facial shapes than healthy kids, but not enough to easily tell them apart.

Flutamide and a new synthetic steroid affected brain and prostate chemicals and showed potential for treating androgen-related conditions and epilepsy.

Seborrhea in Parkinson's disease may be linked to hormones, not autonomic impairment.

PRP therapy may increase hair density in pattern hair loss without serious side effects, but more research is needed.

Men with sleep apnea and low iron levels are more likely to have male-pattern baldness, especially if they have a family history of hair loss.

Certain bacteria can boost lentil growth and improve soil used for farming.

People with hair loss have more androgen receptors and enzymes in certain follicles, with men and women showing different patterns.

Adding platelet-rich plasma improves hair density and thickness in androgenetic alopecia.

Use PRP and ASC-BT for hair loss and wound healing, but more research needed.

Hair loss can significantly affect a person's self-esteem and body image, especially in young people, those who value their looks highly, and women.

Hair restoration can be achieved through non-surgical treatments like minoxidil, antiandrogens, phototherapy, and PRP procedures, or through surgical methods like hair transplantation. Continued treatment is needed to maintain results, and full results are visible after 12-18 months.

The review shows that skin symptoms like chronic fungal infections, hair loss, and skin depigmentation are key for early detection and management of APECED.

Softer hydrogels help wounds heal better with less scarring.

Skin organoids help improve wound healing and tissue repair.

The study found that women with PCOS have more and larger ovarian follicles and differences in ovarian structure, but these features alone can't always diagnose PCOS.

The document suggests that blocking sweat glands with antiperspirants might allow skin-generated hormones to be absorbed, possibly increasing breast and prostate cancer risk.

PRP shows promise in healing but needs a standardized, safe preparation method.

Platelet-Rich Plasma (PRP), a protein-rich extract from a patient's blood, shows promise in improving hair density, thickness, and quality, but the best method of use and number of treatments needed for noticeable results are still unclear.

Platelet-rich plasma, taken from a person's own blood, can help rejuvenate skin, stimulate hair growth, and treat hair loss, but more research is needed to confirm its safety and effectiveness.

The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.