January 2024 in “Revista de la Asociación Colombiana de Dermatología y Cirugía Dermatológica/Revista de la Asociacion Colombiana de Dermatologia y Cirugia Dermatologica” This case report highlights the successful treatment of alopecia areata universalis with Baricitinib, suggesting potential long-term effectiveness of janus kinase inhibitors for this autoimmune hair loss condition.
January 2024 in “International Journal of Dermatology Venereology and Leprosy Sciences” This study reports that an intervention decreased glucose and insulin levels, indicating improved insulin resistance, which is linked to a skin condition called acne vulgaris and other disorders associated with insulin resistance.
December 2023 in “Minia Journal of Medical Research” In this study, researchers found that transverse sections of alopecia areata lesions showed significantly more terminal hair follicles with perifollicular lymphocytic infiltrate compared to longitudinal sections, and this immune infiltration positively correlated with the positive hair pull test in patients.
November 2023 in “Cureus” In this pilot study, a 12-week topical treatment with a lotion containing magnetized saline water significantly increased hair count and hair mass index while activating autophagy in the scalp of 20 Caucasian men with mild-to-moderate androgenetic alopecia.
November 2023 in “Frontiers in pharmacology” This review highlights the ongoing need for novel treatments for autosomal recessive congenital ichthyoses, suggesting that drug repositioning, utilizing existing medications or biologics, could provide more affordable and effective options for managing this lifelong skin condition.
September 2023 in “International journal of women’s dermatology” This study found mixed evidence linking traction hairstyles, previous pregnancies, chemical hair relaxers, and several comorbidities to an increased risk of central centrifugal cicatricial alopecia in Black women.
September 2023 in “Environmental health perspectives. Supplements” This study found that children in Alcalá may have lower exposure to calcium and strontium compared to peers in other regions, based on scalp-hair analysis.
August 2023 in “Research Square (Research Square)” In this study, researchers observed that Melan A, a melanocytic marker, was significantly expressed in hair follicles of alopecia areata patients and correlated with immune infiltrates, suggesting melanocytes might contribute to the autoimmune response in this condition.
July 2023 in “Research Square (Research Square)” This study developed finite element models to examine skin's biomechanical properties, finding that structural heterogeneities like Rete ridges and hair follicles create distinct stress and strain patterns that may influence mechanosensation and skin integrity.
In this retrospective analysis, researchers evaluated 54 patients undergoing soft tissue reconstruction for scalp and forehead defects and reported excellent aesthetic outcomes with local flaps for defects up to 50 cm², while larger defects typically required additional skin grafting.
July 2023 in “Nasza Dermatologia Online” More research is needed on CCCA in children, especially Black and Asian adolescents.
June 2023 in “International Journal of Dermatology” This study reviewed cases of congenital alopecia areata, highlighting a predominance in females and possible genetic factors, and found that topical corticosteroids were effective for hair regrowth in most treated patients, suggesting they are a suitable first-line treatment.
June 2023 in “British journal of dermatology/British journal of dermatology, Supplement” This study suggests that congenital alopecia areata should be considered for newborns with alopecia, supporting the use of topical corticosteroids as a reasonable initial treatment option based on observed regrowth.
January 2023 in “Journal of Cutaneous Pathology” This study found that histopathologic features such as a catagen/telogen shift, melanin in fibrous tracts, and small dystrophic follicles can help differentiate alopecia areata from pattern hair loss in the absence of peribulbar infiltrates.
January 2023 in “International journal of dermatology, venereology and leprosy sciences” This study found that patients with alopecia areata had altered levels of inflammatory and coagulation markers, suggesting an association with disease pathogenesis and potential predictive value.
September 2022 in “Revista de la Asociación Colombiana de Dermatología y Cirugía Dermatológica” This review discusses mucocutaneous manifestations associated with Covid-19, classifies the lesions, and describes their characteristics and treatments but reports no new clinical findings.
August 2022 in “Case reports in medicine” This case report describes a 19-year-old female with systemic lupus erythematosus who exhibited eyelash trichomegaly, a rare disorder involving changes in eyelash characteristics, alongside diffuse alopecia.
June 2022 in “Frontiers in Medicine” This review discusses acupuncture and moxibustion for alopecia and reports evidence suggesting their efficacy for various types of hair loss, but notes barriers like cost and aversion to needles.
January 2022 in “Biocell” This review outlines the potential of mesenchymal stem cells and their derivatives as emerging therapies for atopic dermatitis, but reports no new clinical results; the authors highlight the need for further investigation.
October 2021 in “QJM: An International Journal of Medicine” This study found increased H2O2 levels and decreased E-cadherin levels in vitiligo patients compared to controls, suggesting oxidative stress and compromised cell adhesion may impact the pigmentary system in vitiligo-affected skin.
October 2021 in “Journal of Investigative Dermatology” This study found that fibroblasts from mature skin showed significantly reduced mechanical force production compared to young skin fibroblasts, suggesting age-related changes in cellular mechanical properties.
January 2021 in “Our Dermatology Online” This case report describes a patient with alopecia universalis who had an excellent and persistent response to oral tofacitinib treatment after one year.
June 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that the HoxC gene cluster is crucial for the development of hair and nails in mice, with key regulation by two mammalian-specific enhancers.
January 2020 in “Ayurline: IJ-RIM” This study found that Eclipta alba Hassk. (Bhrungraj) significantly inhibited the growth of human liver cancer cells, suggesting its potential as an anticancer agent.
August 2018 in “bioRxiv (Cold Spring Harbor Laboratory)” This study identifies diltiazem as a promising repurposed drug for treating influenza, supported by its antiviral activity and gene modulation effects, leading to a Phase II clinical trial authorization.
This study shows that multiphoton microscopy can non-invasively distinguish scarring from non-scarring alopecia by identifying specific morphological features in hair follicle structures.
March 2015 in “Zagazig University Medical Journal” The study found that CK15 expression, representing hair follicle stem cell activity, was reduced or absent in scarred primary cicatricial alopecia lesions, suggesting stem cell damage may contribute to the scarring process.
December 2014 in “Sociedad (University of Buenos Aires)” This study highlights three cases of liver toxicity linked to the use of the green tea catechin-containing supplement Inneov masa capilar® and underscores the need for careful monitoring of such products.
November 2014 in “Springer eBooks” Using a patient's own tissue for browlifting can improve both the position and fullness of the brow for a longer-lasting rejuvenation.
December 2012 in “Bulletin of Egyptian Society for Physiological Sciences” This study found that topical application of copper (II) albumin complex improved healing signs in rats with full thickness thermal burns, enhancing antioxidant, anti-inflammatory, and pain modulating effects.