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Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

The ZIP7 gene helps control zinc levels in cells by moving zinc from the Golgi apparatus to the cytoplasm.

Hair follicle development and microbes help regulatory T cells gather in newborn skin.

Androgens may cause hair loss by increasing TGF-beta1 from scalp cells, which inhibits hair cell growth.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Bone Morphogenetic Proteins (BMPs) help control skin health, hair growth, and color, and could potentially be used to treat skin and hair disorders.

Different types of skin cells have unique genetic markers that affect how likely they are to spread cancer.

Hair loss needs more research for better treatments.

Flutamide is more effective and has fewer side effects than spironolactone for treating hirsutism.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Androgens can cause hair growth in some areas and hair loss on the scalp.

Estrogen therapy can reduce skin aging but has cancer risks.

Cathepsin L is essential for normal hair growth and development.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

Estrogen replacement can improve skin health in menopausal women but doesn't reverse sun damage or prevent hair loss.

Matriptase is crucial for keeping epithelial tissues healthy and functioning properly.

Estrogen loss during menopause worsens skin health, but hormone replacement therapy may improve it, though more research is needed.

Flutamide effectively reduced excessive hair growth and improved related symptoms in hirsutism patients without significant side effects.

Prolactin contributes to hair loss by promoting hair follicle shrinkage and cell death.

Mice hair growth patterns get more complex with age and can change with events like pregnancy or injury.

Cepharanthine is a well-tolerated drug with multiple medical uses, including anti-inflammatory and anti-cancer properties.

Hair follicles produce and respond to melatonin, affecting hair growth and sensitivity to estrogen.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Potassium channel openers are effective in treating heart conditions, high blood pressure, pulmonary diseases, bladder issues, and hair loss, but more selective drugs are needed.

The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.

Hormones, especially androgens, play a big role in acne, but most acne sufferers don't have a hormone disorder. Hormonal treatments, including birth control pills, can be very effective for women whose acne doesn't improve with regular treatments.

Exposure to finasteride in the womb caused lasting reproductive issues in male rats.

Flutamide rarely causes liver toxicity in prostate cancer patients.

The research found that Atypical Progeroid Syndrome has unique symptoms and is not caused by the buildup of a certain mutant protein.