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The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Sonic hedgehog signaling is crucial for hair growth and maintaining hair follicle identity.

Prolactin contributes to hair loss by promoting hair follicle shrinkage and cell death.

Hormones, especially androgens, play a big role in acne, but most acne sufferers don't have a hormone disorder. Hormonal treatments, including birth control pills, can be very effective for women whose acne doesn't improve with regular treatments.

ICG-enhanced NIR laser therapy may be a promising acne treatment with improvement and no side effects.

Hormonal treatments, including birth control and antiandrogens, can effectively treat acne in women.

Prolactin affects hair growth cycles and can cause early hair follicle regression.

Blocking β-catenin in skin cells improves hair growth during wound healing.

SAHA syndrome is a condition in women involving skin and hair issues, often related to hormonal imbalances, and is treated based on the underlying cause.

Finasteride reduces hairiness and androgen levels in women with unexplained excessive hair growth.

Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.

Msx2 and Foxn1 are both crucial for hair growth and health.

Hidradenitis suppurativa treatment should be tailored to the individual, with quitting smoking being important.

Maintaining the right amount of retinoic acid is crucial for healthy hair and skin.

Testosterone therapy can help improve sexual desire and function in postmenopausal women but may cause side effects and is not FDA-approved for this use.

New treatments for a chronic skin condition show promise, but individualized plans are crucial due to varying responses.

CD98hc's role in skin health decreases with age.

Activating Notch in adult skin causes T cells and neural crest cells to gather, leading to skin issues.

Mice without collagen VI have slower hair growth normally but faster regrowth after injury.

Hair can regrow in large wounds through a process similar to how hair forms in embryos, and understanding this could lead to new treatments for hair loss or scarring.

The review found that different stem cell types in the skin are crucial for repair and could help treat skin diseases and cancer.

PlncRNA-1 helps hair follicle stem cells grow and develop by controlling a specific cell signaling pathway.

Wnt1a helps keep cells that can grow hair effective for potential hair loss treatments.

Many treatments for hair loss lack proper testing and FDA approval, so their effectiveness is uncertain.

Testosterone therapy can help improve mood, sexual function, and bone health in women with low androgen levels, but more research is needed to establish safe and effective guidelines.

The document concludes that careful evaluation is needed to diagnose PCOS correctly due to similar symptoms in other conditions, and accurate testosterone level measurement is crucial.

Lactoferrin helps mice grow hair by increasing cell growth and hair follicle development.

Dihydrotestosterone causes p27 protein breakdown in ovarian and breast cancer cells by binding with SKP2.

New markers and pathways have been found in skin tumors, helping better understand and diagnose them.

Hair follicles are essential for skin health, aiding in hair growth, wound healing, and immune function.