research Investigations on Kaempferol, Quercetin, and Other Flavonoids in Aquatic Plants of Iraqi Marshlands
Flavonoids in Iraqi marshland plants have potential health benefits like antioxidant and anti-inflammatory effects.
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research Neuroendocrine Controls of Keratin Expression in Human Skin
Neurohormones help control skin health and could treat skin disorders.
research Possible Role of Autophagy Activation in Stimulation of Regeneration
The document suggests that activating autophagy might help with regeneration by removing old and damaged cells.
research FLCN Regulates Transferrin Receptor 1 Transport and Iron Homeostasis
FLCN helps control iron levels in cells.
research Tissue Engineering and Regenerative Medicine: Achievements, Future, and Sustainability in Asia
Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.
research 5-Bromo-3,4-Dihydroxybenzaldehyde Promotes Hair Growth Through Activation of Wnt/β-Catenin and Autophagy Pathways and Inhibition of TGF-β Pathways in Dermal Papilla Cells
5-Bromo-3,4-dihydroxybenzaldehyde could potentially help hair growth by activating certain cell pathways and inhibiting others.
research Fibrodysplasia Ossificans Progressiva: A Segmental Progeroid Syndrome
Fibrodysplasia ossificans progressiva is a rare genetic disorder that causes extra bone growth and symptoms of premature aging.
research Montagna Symposium 2013: Light and Skin - How Light Sustains, Damages, Treats, Images, and Modifies Skin Biology
Light affects skin health, aging, and cancer risk, and new light-based treatments and imaging are promising for skin care.
research Long-Term Differential Changes in Mouse Intestinal Metabolomics After Gamma and Heavy Ion Radiation Exposure
Heavy ion radiation has a more severe and long-lasting effect on mouse intestinal metabolites than gamma radiation.
research Antroquinonol Exerts Immunosuppressive Effect on CD8+ T Cell Proliferation and Activation to Resist Depigmentation Induced by H2O2
Antroquinonol may help prevent skin depigmentation by suppressing certain immune cells.
research Roles of Wnt7a in Embryo Development, Tissue Homeostasis, and Human Diseases
Wnt7a protein is crucial for development and tissue maintenance and plays varying roles in diseases and potential treatments.
research Synthetic Approaches for Pharmacologically Active Decorated Six-Membered Diazines
The document concludes that specific methods for making diazine-based drugs can lead to high yields and are important for creating effective treatments for various diseases.
research Air Pollution, Autophagy, and Skin Aging: Impact of Particulate Matter on Human Dermal Fibroblasts
Air pollution (PM10) increases skin inflammation and aging by reducing collagen and may trigger a repair response in skin cells.
research Histogenesis of Keratoacanthoma: Histochemical and Immunohistochemical Study
Keratoacanthoma comes from hair follicle cells.
research Impaired LEF1 Activation Accelerates iPSC-Derived Keratinocytes Differentiation in Hutchinson-Gilford Progeria Syndrome
Faulty LEF1 activation causes faster skin cell differentiation in premature aging syndrome.
research Novel Potential Therapeutic Targets of Alopecia Areata
New treatments for hair loss from alopecia areata may include targeting immune cells, using stem cells, balancing gut bacteria, applying fatty acids, and using JAK inhibitors.
research The Paradox of p53: What, How, and Why?
The p53 protein has complex, sometimes contradictory functions, including tumor suppression and promoting cell survival.
research Potential Role and Therapeutic Interests of Myo-Inositol in Metabolic Diseases
Myo-inositol supplements may improve insulin sensitivity and help with conditions like PCOS and gestational diabetes, but more research is needed.
research Identifying the Target Cells and Mechanisms of Merkel Cell Polyomavirus Infection
Human dermal fibroblasts are the main cells targeted by a virus that can cause a deadly skin cancer, and a certain inhibitor can effectively block this infection.
research An Integrative View of Mammalian Seasonal Neuroendocrinology
The article concludes that better understanding gene regulation related to seasonal changes can offer insights into the mechanisms of seasonal timing in mammals.
research Three-Dimensional Proteome-Wide Scale Screening for the 5-Alpha Reductase Inhibitor Finasteride: Identification of a Novel Off-Target
Finasteride may affect PNMT, causing side effects.
research Complementary Evolution of Coding and Noncoding Sequence Underlies Mammalian Hairlessness
Hairless mammals have genetic changes in both their protein-coding and regulatory sequences related to hair.
research Identification of Transcriptional Targets of Wnt/β-Catenin Signaling in Dermal Papilla Cells of Human Scalp Hair Follicles: EP2 Is a Novel Transcriptional Target of Wnt3a
Wnt3a activates certain genes in hair follicle cells, including a newly discovered one, EP2, which may affect hair growth.
research Human Hair Follicles Are an Extrarenal Source and a Nonhematopoietic Target of Erythropoietin
Human hair follicles produce and respond to erythropoietin, helping protect against stress.
research Identification of Dkk4 as a Target of Eda-A1/Edar Pathway Reveals an Unexpected Role of Ectodysplasin as Inhibitor of Wnt Signaling in Ectodermal Placodes
Ectodysplasin inhibits Wnt signaling to help form hair follicles.
research Complementary Evolution of Coding and Noncoding Sequence Underlies Mammalian Hairlessness
Both gene and non-gene areas of DNA evolved to make some mammals hairless.
research Wnt Target Gene Ascl4 Is Dispensable for Skin Appendage Development
The gene Ascl4 is not necessary for the development of hair, teeth, or mammary glands.
research Editor's Evaluation: Complementary Evolution of Coding and Noncoding Sequence Underlies Mammalian Hairlessness
Hairlessness in mammals is due to complex genetic changes in both genes and regulatory regions.
research Role of Dermal Factors Involved in Regulating the Melanin and Melanogenesis of Mammalian Melanocytes in Normal and Abnormal Skin
Dermal factors are crucial in regulating melanin production in skin.
research Dermatologic Manifestations of Mitochondrial Dysfunction: A Review of the Literature
Mitochondrial dysfunction is linked to various skin conditions and could be a target for treatments.