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IL-1 family cytokines are crucial for skin defense and healing, but their imbalance can cause skin diseases.

Vitamin D is crucial for bone health and preventing serious diseases.

The document adds two cases of Gomez-Lopez-Hernandez syndrome and suggests including trigeminal anesthesia and scalp alopecia as key diagnostic criteria.

TGM3 is important for skin and hair structure and may help diagnose cancer.

Vitamin D receptor is important for regulating hair growth and wound healing in mice.

Biologics show promise in treating various stubborn skin diseases, but more research and better reimbursement criteria are needed.

Cognitions significantly influence Trichotillomania, suggesting cognitive therapies could help.

A gene variant increases the risk of a type of hair loss by affecting hair protein production.

Testosterone therapy helps boys with hormone deficiencies develop normal male characteristics and grow properly.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

Hormone therapy for prostate cancer can increase heart risks, especially in men with heart conditions.

The vitamin D receptor helps regulate skin and hair health independently of its usual vitamin D ligand.

Long-term use of finasteride and dutasteride can cause serious health issues like diabetes and liver problems.

Azathioprine caused side effects in over half of the Korean pediatric inflammatory bowel disease patients, requiring close monitoring.

Topical immunotherapy is the best treatment for severe alopecia areata.

Zinc pyrithione needs targeted delivery to the scalp for effective dandruff treatment.

Basonuclin 2 is vital for the development of facial bones, hair follicles, and male germ cells in adult mice, and its absence can lead to dwarfism and abnormal follicles.

Targeting a protein that blocks hair growth with microRNAs could lead to new hair loss treatments, but more research is needed.

Removing certain brain receptors in mice worsens seizure severity and response to treatment during hormone withdrawal.

Bolandiol, a synthetic steroid, builds muscle and bone without greatly affecting sex glands, and works differently from other hormones.

Knocking out certain genes in mice helps understand skin and hair growth problems.

Transgender youth have more sleep disorders, but gender-affirming therapy may help reduce them.

Drinking a lot of alcohol increases the risk of prostate cancer and can worsen the condition.

Nanofat shows promise for facial rejuvenation and treating skin issues but needs more research for long-term safety.

Transglutaminase activity is important for skin and is found in both mammals and birds.

FGF21 can help reduce skin inflammation caused by C. acnes.

Common skin conditions can greatly affect a person's mental health and social life.

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The study found that genetic differences related to hair growth and other traits help cashmere goats adapt to high-altitude environments.

Collagen-enhanced mesenchymal stem cells significantly improve skin wound healing.