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Vitiligo is a skin condition causing white spots, more common in women, often starts before age 20, and can affect mental health.

Keratins help protect cells, aid in cancer diagnosis, and influence cancer behavior and treatment.

Coumarin derivatives show promise as anti-estrogenic agents for treating breast cancer, with some in clinical trials.

Air pollution worsens skin diseases and aging by causing inflammation and oxidative stress.

Chemotherapy can cause various skin reactions, with hair loss being the most common, and proper diagnosis and treatment of these reactions are important.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Hair color production in mice is closely linked to the hair growth phase and may also influence hair growth itself.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

Melatonin may benefit skin health and could be a promising treatment in dermatology.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

Alopecia areata causes hair loss, has no cure, and various treatments exist.

The document concludes that accurate diagnosis of ichthyosis is crucial for treatment and genetic advice, and ongoing research is needed for better therapies.

Cancer cells often have more copies of TERT and TERC genes, which helps them grow and could affect patient outcomes.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

Eczema and fungal infections are the most common skin problems in Japan, with different age groups and genders affected by various conditions.

Estrogen replacement can improve skin health in menopausal women but doesn't reverse sun damage or prevent hair loss.

Estrogen loss during menopause worsens skin health, but hormone replacement therapy may improve it, though more research is needed.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

In Italian patients with lupus, the most common skin issue was chronic cutaneous lupus, especially discoid lesions, and nonspecific skin problems occurred in about a third of those with systemic lupus, mainly during active disease.

Hair follicles produce and respond to melatonin, affecting hair growth and sensitivity to estrogen.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

Finasteride and minoxidil are effective for hair regrowth, while treatments for alopecia areata have varying success and continuous treatment is necessary.

Smoking harms the skin, causing early aging and increasing cancer risk, but stopping smoking can improve skin health.

Melatonin helps regulate hair growth and protects the hair follicle from stress.

Hair color production is closely linked to the active growth phase of hair in mice and may also influence hair growth itself.

Oral retinoids are effective for various skin conditions but have side effects and should not be used during pregnancy.

People with alopecia areata often have other health issues like skin diseases, metabolic syndrome, stomach infections, lupus, anemia, thyroid problems, mental health issues, vitamin D deficiency, and hearing and eye problems.

Certain genes control the color of human hair by affecting pigment production.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.