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Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.

Insulin resistance may contribute to various skin diseases and treating it could improve skin health and prevent more serious conditions.

Pregnancy causes skin changes like darkening, hair thickening, nail changes, and increased risk of skin growths, most of which usually resolve after birth.

Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.

Maintaining DNA health in stem cells is key to preventing aging and tissue breakdown.

The nude gene causes skin cell overgrowth and improper development, leading to hair and urinary issues.

Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.

Tissue-resident memory T cells can protect against infections and cancer but may also contribute to autoimmune diseases.

Hair greying is caused by oxidative stress damaging hair follicles and melanocytes.

European guidelines recommend regular eye and ear exams, skin care, vitamin D supplements, and cautious use of medications for managing congenital ichthyoses.

Inactive hair follicle stem cells help prevent skin cancer.

Skin problems can be caused or worsened by physical forces and pressure on the skin.

Skin fat has important roles in hair growth, skin repair, immune defense, and aging, and could be targeted for skin and hair treatments.

The document concludes that early recognition and treatment of primary cicatricial alopecia is crucial to prevent permanent hair loss.

Cancer development is like natural selection, involving mutated cells and environmental factors.

The 308-nm excimer laser is a promising treatment for vitiligo with varying success and mild side effects.

Some drugs can cause hair loss, and stopping these drugs often leads to hair regrowth.

Vitiligo causes white skin patches and is linked to autoimmune issues.

Epidermal stem cells could lead to new treatments for skin and hair disorders.

Coffee silverskin may be a beneficial and safe ingredient for cosmetics, offering hydration, firmness, and potential hair growth benefits.

The review recommends hormone replacement therapy for women with premature ovarian insufficiency to manage symptoms and protect health, with specific approaches for different groups.

PPAR agonists show promise for skin conditions but need more research before being a main treatment.

Nanotechnology in dermatology shows promise for better drug delivery and treatment effectiveness but requires more safety research.

Apoptosis is crucial for healthy skin and treating skin diseases.

Mitoxantrone with a corticosteroid helps manage symptoms for some advanced prostate cancer patients but doesn't extend life.

Both mouse and rat models are effective for testing alopecia areata treatments.

Graft-versus-host disease is a complication where donor immune cells attack the recipient's body, often affecting the skin, liver, and gastrointestinal tract.

Hair loss can indicate underlying systemic diseases and addressing these can sometimes reverse the hair loss.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

Celiac disease can cause skin problems that may get better with a gluten-free diet.