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Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Interferons are effective for some skin conditions and cancers, but can have side effects and need more research for optimal use.

Nano-Pulse Stimulation™ Therapy is more effective and less damaging than cryoablation for treating melanoma tumors in mice.

Pediatric transplant patients often experience unique skin changes mainly due to medication use.

Mice without the vitamin D receptor are more prone to UV-induced skin tumors.

The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.

Adrenal disorders can cause lasting brain and behavior issues in children.

Hirsutism is excessive male-pattern hair growth in women, often caused by hormonal imbalances, and requires ongoing treatment to manage.

The document says that treating the root cause of hair follicle damage is crucial to prevent permanent hair loss, and treatment options vary.

Rapamycin reduces skin cell growth and tumor development by affecting cell signaling in mice.

OCIAD2 and DCN genes affect hair growth in goats by having opposite effects on a growth signaling pathway and inhibiting each other.

GnRH analogues are effective for diagnosing and treating female androgen excess, offering a non-surgical option.

Non-invasive imaging helped diagnose a woman's severe hormone imbalance and diabetes, and medication successfully treated her condition.

Targeting the HEDGEHOG-GLI1 pathway could help treat keloids.

Diabetes can cause a variety of skin disorders, some of which may signal more serious health issues.

Hirsutism in teens is often due to polycystic ovarian syndrome and needs careful assessment and support.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.

Researchers developed promising agents for prostate cancer imaging, with the best one showing high potential for clinical use.

Keratin 15 is not a reliable sole marker for identifying epidermal stem cells because it's found in various cell types.

Methotrexate is a key, cost-effective drug for skin conditions, but requires careful monitoring for side effects.

Hirsutism is excessive hair growth in women often caused by polycystic ovarian syndrome, and identifying the cause is important for managing associated health risks.

Inactive hair follicle stem cells help prevent skin cancer.

Research on epidermal stem cells has advanced significantly, showing promise for improved clinical therapies.

Skin health and diseases are closely linked to metabolic processes.

A man developed skin cancer on his scalp after multiple artificial hair grafts.

Cytokines are important for immune responses and treating diseases, but they can cause side effects like fever and skin issues.

Prednisone reduces organ mast cell infiltration but does not alter the abnormal appearance of mast cells in systemic mastocytosis.