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Hair microscopy is a simple and cost-effective method to help diagnose systemic diseases in children.

Acitretin is effective for severe skin conditions but has significant side effects and requires careful monitoring.

Understanding how DHT works is important for diagnosing and treating hormone-related disorders.

We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.

HLA-DRB5 and other genes may be linked to alopecia universalis.

Pediatric endocrinologists should provide early fertility counseling and preservation options to young patients at risk of infertility.

Soy protein with isoflavones reduces wrinkles and improves skin hydration in postmenopausal women.

Using mesenchymal stem cells or their exosomes is safe for COVID-19 patients and helps improve lung healing and oxygen levels.

Urologists should monitor mental health in patients taking finasteride due to potential links to suicidal thoughts, adjusting dosage or stopping use if necessary. More research is needed to confirm if finasteride causes these thoughts.

Rare ULBP3 gene changes may raise the risk of Alopecia areata, a certain FAS gene deletion could cause a dysfunctional protein in an immune disorder, and having one copy of a specific genetic deletion is okay, but two copies cause sickle cell disease.

Retinoic acid helps change skin cells and is important for skin development and hair growth.

Enzymes called 5α-reductases have many body functions and need more research to safely use inhibitors.

Acne is linked to inflammation and insulin resistance, and is associated with various syndromes that require different treatments.

RANK is a key target in breast cancer treatment due to its role in tumor growth and bone metastasis.

A pineal tumor caused a boy's early puberty, which changed from peripheral to central after treatment.

Intravital imaging helps us better understand stem cells in their natural environment and could improve knowledge of organ regeneration and cancer development.

Amenorrhea is relatively rare and initial testing should check FSH, TSH, and prolactin levels.

Hair and nail changes can indicate health issues, including cancer and side effects from cancer treatments.

A Japanese bone marrow transplant patient developed a rare skin cancer possibly linked to long-term use of the medication voriconazole.

The document concludes that the development of certain tumors is influenced by genetic background and that a specific gene modification can lead to tumor regression and reduced growth.

Bone-marrow and epidermal stem cells help heal wounds differently, with bone-marrow cells aiding in blood vessel formation and epidermal cells in hair growth.

PTHrP is important for bone formation and may be targeted for osteoporosis treatment and longevity therapies.

Testosterone treatment can improve sexual function and bone density in women but may have adverse effects and requires more research on safety and guidelines.

Scalp cooling significantly reduces hair loss in chemotherapy patients.

The document concludes that careful evaluation is needed to diagnose PCOS correctly due to similar symptoms in other conditions, and accurate testosterone level measurement is crucial.

High androgen levels can cause excessive hair growth and may indicate serious health issues, including heart disease and fertility problems.

Early diagnosis and treatment with Leuprolide are key for children with precocious puberty.

Cell-based therapies show promise for treating Limbal Stem Cell Deficiency but need more research.

Testosterone therapy seems safe and effective for transgender men with proper care, but more long-term research is needed.

Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.