research Effect of 5α-Dihydrotestosterone and Testosterone on Apoptosis in Human Dermal Papilla Cells
High levels of testosterone and 5α-DHT can lead to cell death in cells important for hair growth.
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research Reply to 'What Is the Effect of Obesity on the Folliculosebaceous Unit?'
Obesity is linked to more severe hair loss in adult men and to excess hair growth, but its effects on hair conditions are complex and need more research.
research Analysis of the MicroRNA Expression Profile of Normal Human Dermal Papilla Cells Treated with 5α-Dihydrotestosterone
DHT affects hair follicle cells by changing microRNA levels, leading to less cell growth and more cell death.
research A Diagnostically Challenging Case of Hyperandrogenism in a Postmenopausal Woman
The case highlights the complexity of diagnosing high testosterone in older women and the need for thorough testing.
research Virilization in a Postmenopausal Woman: Ovarian Leydig Cell Tumor
A postmenopausal woman's virilization was caused by a rare ovarian tumor that was hard to detect but was successfully treated with surgery.
research Hormonal Treatment Strategies Tailored to Non-Binary Transgender Individuals
Non-binary transgender individuals need personalized hormonal treatments for better well-being and quality of life.
research Safety and Compatibility of a New Nourishing Baby Shampoo and Tip to Toe Wash with Stearic Acid
The new baby shampoo and wash with stearic acid is safe and potentially effective for nourishing babies' skin.
research Dermatologic Therapy: December 1987 to December 1988
New skin treatments in 1987-1988 showed effectiveness for various conditions, but some had side effects or risks.
research Visually Scoring Hirsutism
The modified Ferriman-Gallwey method is a useful tool for diagnosing hirsutism.
research Hirsutism
Hirsutism, often caused by PCOS, is treated with medication and weight loss is important for obese women with PCOS.
research Recent Advances in the Molecular Mechanisms Causing Primary Generalized Glucocorticoid Resistance
Mutations in the NR3C1 gene cause a rare condition that affects hormone signaling and can lead to various symptoms, with dexamethasone as a treatment option.
research Short- and Long-Term Clinical Skin Effects of Testosterone Treatment in Trans Men
Testosterone treatment in trans men increases body and facial hair and may lead to hair loss over time, but severe skin issues are rare.
research Stem Cells and Alopecia: A Review of Pathogenesis
Damaged hair follicle stem cells can cause permanent hair loss, but understanding their role could lead to new treatments.
research Alopecias: Practical Tips for the Management of Biopsies and Main Diagnostic Clues for General Pathologists and Dermatopathologists
The document concludes that understanding hair follicle histology and the hair cycle is crucial for diagnosing alopecia.
research Histopathologic Evaluation of Alopecias
The document concludes that accurate diagnosis of different types of hair loss requires careful examination of hair and scalp tissue, considering both clinical and microscopic features.
research Literature Review of Cosmetic Procedures in Men: Approaches and Techniques Are Gender Specific
Men prefer less invasive cosmetic procedures and need different treatment approaches than women.
research Molecular Genetics of Alopecias
Scientists have found specific genes linked to different hair loss conditions, which could lead to new treatments.
research Alopecia and Clinical Presentation of Endocrinopathies: Pathogenetic and Diagnostic Aspects
Hormonal imbalances can cause hair loss, and understanding them can help develop better treatments.
research A Pure Androgen-Secreting Adrenal Cortical Tumor in a 13-Year-Old Female
A 13-year-old girl's masculine symptoms improved after surgery for a rare adrenal tumor that produced male hormones.
research Cutaneous Manifestations of Polycystic Ovary Syndrome
Skin problems like acne and excess hair in PCOS are common and linked to being overweight.
research A Study to Assess the Efficacy of Fractional Carbon Dioxide Laser with Topical Platelet-Rich Plasma in the Treatment of Androgenetic Alopecia
Using a carbon dioxide laser and platelet-rich plasma together can effectively restore hair and patients are generally satisfied with the results.
research Role of Genetics and Sex Steroid Hormones in Male Androgenetic Alopecia and Female Pattern Hair Loss: An Update
Genetics and hormones play a role in male and female hair loss, but more research is needed to fully understand it.
research Viable Terminal Scalp Hair Follicles Are Necessary and Sufficient for Clinical Efficacy of Finasteride in Male Pattern Hair Loss
Finasteride works for hair loss by maintaining existing hair follicles, not reversing miniaturization.
research A Pilot Evaluation of Scalp Skin Wounding to Promote Hair Growth in Female Pattern Hair Loss
Scalp micro-wounding helps promote hair growth in female pattern hair loss.
research Delaying Treatment in Male-Pattern Hair Loss Affects the Therapeutic Response
Delaying hair loss treatment reduces its effectiveness.
research Lyophilized Growth Factor Intralesional Injection in Female Pattern Hair Loss: A Clinical and Trichoscopic Study
Injections improve hair growth, density, and thickness in women safely.
research Medical Treatments for Male and Female Pattern Hair Loss
Minoxidil and finasteride treat hair loss in men, while minoxidil treats hair loss in women.
research Evaluation of Androgens in the Scalp Hair and Plasma of Patients with Male-Pattern Baldness Before and After Finasteride Administration
Finasteride lowers scalp and blood DHT levels, potentially treating male-pattern baldness.
research Quality of Life Issues in Male Pattern Hair Loss
Male pattern hair loss negatively affects quality of life, but drug treatments can help.
research Long-Term Treatment with Finasteride 1 mg Decreases the Likelihood of Developing Further Visible Hair Loss in Men with Androgenetic Alopecia
Finasteride 1 mg helps prevent more hair loss in men with male pattern baldness.