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Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.

Bisphenol-A (BPA) increases connections between brain cells and boosts their activity, but it blocks the effects of a male hormone on brain cell plasticity.

Postpartum depression is linked to changes in brain chemicals, inflammation, stress, and certain genes, and can potentially be identified by markers like specific steroids, serotonin levels, and vitamin D levels.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Monkeys with more anxious or inhibited temperaments tend to have less hair loss.

Toxoplasma gondii infection may increase testosterone levels in males.

Sons of mothers with polycystic ovary syndrome (PCOS) have a higher risk of obesity and insulin resistance, possibly due to certain genes and factors passed down from their mothers.

Allopregnanolone can reduce gut inflammation and normalize neurotransmitter levels after finasteride withdrawal.

Alcohol in teen years leads to more adult drinking, finasteride doesn't help.

Early hormones shape sex-specific differences in rat glands.

Finasteride reduces alcohol withdrawal severity and anxiety in mice, but may increase withdrawal severity in some cases.

In Japan, sex reassignment surgery for gender identity disorder faces challenges and needs better medical support and education.

Blocking androgen activity in newborn rats affects body weight and appetite-related hormones differently in males and females.

PCOS is a complex disorder in women that can lead to various health risks and requires personalized treatment.

Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.

Myo-inositol helps improve skin conditions and metabolic profiles in young women with PCOS.

Intense exercise at night can delay the body's internal clock gene expression by 2 to 4 hours.

Drugs for hormone-related conditions might help treat mental disorders but could have serious side effects.

The document concludes that sex hormones and related compounds have various effects on health, with both potential benefits and risks.

Neuroactive steroids show promise for treating mental and neurological disorders by targeting GABA_A receptors.

5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.

Women with PCOS have a higher risk of diabetes, heart problems, certain cancers, and mental health issues, but early treatment can help manage these risks.

Chronic stress in mice changes skin metabolism and gene expression, leading to hair loss.

PCOS often leads to sleep problems, especially obstructive sleep apnea, affecting overall health.

Stress and alcohol affect brain chemicals differently in rats, mice, and humans, influenced by genetic differences.

TRPV3 could be a target for treating pain, skin disorders, and hair problems, but more research is needed to create effective drugs.

Nanotechnology could improve hair regrowth but faces challenges like complexity and safety concerns.

Using three different drugs together may better treat eye diseases like glaucoma and macular degeneration.

5-alpha reductase inhibitors, like finasteride and dutasteride, may cause depression, but more research is needed to understand why.

Certain gut bacteria may increase or decrease the risk of male pattern baldness.