research Endocrine Influences on Hair Growth
Hormones and genetics affect hair growth and patterns, with some changes reversible and others not.
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research Regulatory Roles of Androgens in Cutaneous Wound Healing
Testosterone may slow down wound healing and increase inflammation.
research LY191704: A Selective, Nonsteroidal Inhibitor of Human Steroid 5 Alpha-Reductase Type 1
LY191704 is a compound that effectively blocks a specific enzyme involved in hormone conversion and could help treat enlarged prostate and hair loss.
research Analysis of Hormone Antagonists in Clinical and Municipal Wastewater by Isotopic Dilution Liquid Chromatography Tandem Mass Spectrometry
Researchers developed a method to detect hormone-blocking drugs in wastewater and found them in Beijing's sewage, suggesting they can survive sewage treatment.
research Personality Disorders and Psychopathologic Symptoms in Patients With Androgenetic Alopecia
People with androgenetic alopecia have more personality disorders and mental health symptoms; treatment may help.
research Treatment of Hirsutism and Acne with Cyproterone Acetate
Cyproterone acetate is effective for treating hirsutism and acne but less so for hair loss, with side effects similar to birth control pills.
research An Update on Plant-Derived Anti-Androgens
Some plant-derived compounds may help with hormonal conditions, but more research is needed to confirm their effectiveness.
research Familial and Sporadic Porphyria Cutanea Tarda
Most patients with Porphyria Cutanea Tarda had skin blisters and were often affected by hepatitis C and alcohol abuse, with differences between familial and sporadic cases.
research Gender-Affirming Hormone Therapy for Transgender Females
Hormone therapy for transgender females increases the risk of blood clots and requires careful dosing, monitoring, and lifelong management.
research Hirsutism: Diagnosis and Treatment
The document concludes that proper diagnosis and combined treatments are key for hirsutism management, and weight loss may help overweight patients.
research Kerion Celsi: A Clinical Epidemiological Study
Early diagnosis and effective treatment of kerion Celsi prevent scarring and permanent hair loss.
research Clinical Risk Factors Associated with Intraoperative Floppy Iris Syndrome: A Prospective Study
Taking tamsulosin or finasteride and being older increase the risk of floppy iris during cataract surgery.
research Alopecia: Unapproved Treatments or Indications
Many treatments for hair loss lack proper testing and FDA approval, so their effectiveness is uncertain.
research Issues in Transgender Dermatology: A Systematic Review of the Literature
The review highlights the need for more research on transgender dermatology, the role of dermatologists in gender affirmation, and the effects of hormone therapy on skin and hair.
research Solubilities of Flutamide, Dutasteride, and Finasteride as Antiandrogenic Agents in Supercritical Carbon Dioxide: Measurement and Correlation
Flutamide, dutasteride, and finasteride dissolve differently in supercritical carbon dioxide, with dutasteride dissolving the least.
research Clinical Updates in Hair
Most treatments for hair loss in 1997 were not effective for most people, and maintaining hair growth was difficult.
research Dermatological Problems of Puberty
Puberty often causes skin issues like acne and excessive sweating, and treatments require patience as results may vary.
research Safety Aspects of Androgen Treatment with 5α-Dihydrotestosterone
DHT is a strong androgen that may pose less risk to the prostate compared to testosterone.
research Effectiveness of Treatments for Postpartum Alopecia
No effective treatment for hair loss after childbirth was found, but it usually gets better on its own and some cosmetic methods might help.
research Discovery of Natural Steroid 5 Alpha-Reductase Inhibitors
Natural herbal compounds might treat certain medical conditions by reducing DHT levels, but more research is needed to confirm their effectiveness and safety.
research Predominant Expression of 5 Alpha-Reductase Type 1 in Pubic Skin from Normal Subjects and Hirsute Patients
The main enzyme found in pubic skin that could be targeted to treat excessive hair growth is 5 alpha-R2.
research Endocrine Treatment of Benign Prostatic Hypertrophy: Current Concepts
New hormonal treatments for enlarged prostate show promise for safer, effective non-surgical options.
research Steady-State Pharmacokinetics of Oral Testosterone Undecanoate with Concomitant Inhibition of 5α-Reductase by Finasteride
Finasteride doesn't affect oral testosterone undecanoate, and high DHT levels may cause acne, prostate issues, and hair loss.
research The Use of Plants in Hair and Scalp Preparations
Plant-based ingredients in hair care are being replaced by synthetic alternatives.
research Big Head? Bald Head! Skull Expansion: Alternative Model for the Primary Mechanism of Androgenetic Alopecia
The paper suggests that hair loss might be caused by skull growth, not just DHT's effect on hair follicles, and calls for more research.
research In Vivo Uptake and Metabolism of Testosterone by the Skin and Other Tissues of the Rat
Rat skin takes up and processes testosterone differently than other organs, with testosterone being more important for the skin than its metabolite 5α-DHT.
research Polycystic Ovarian Syndrome and Associated Hirsutism in Adolescents
Early diagnosis and treatment of PCOS in teenagers can help prevent more severe adult PCOS.
research Pharmacokinetics of Two Novel Formulations of Modified-Release Oral Testosterone Alone and With Finasteride in Normal Men With Experimental Hypogonadism
New oral testosterone formulations show potential for safer, effective hormone replacement in men with low testosterone.
research Plasma Zinc Levels in Males with Androgenetic Alopecia as Possible Predictors of Conservative Therapy Effectiveness
Lower zinc levels may predict less effective hair loss treatment.
research Effects of Testosterone on the Expression of Connexin 26 and Connexin 43 in the Uterus of Rats During Early Pregnancy
Testosterone changes important cell communication proteins in pregnant rats' uteruses, which might affect pregnancy success.