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New genes and pathways are important for testosterone production and male sexual development.

Premature balding in some men may be linked to altered hormones, but it's not the male equivalent to polycystic ovary syndrome or metabolic syndrome.

Male hormones and their interactions are crucial for male sexual development and characteristics.

Hormone therapy with estradiol and spironolactone can regrow scalp hair in transgender women by lowering testosterone to female levels.

5α-reductase inhibitors help treat disorders caused by DHT and have potential for future therapies.

Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.

Young men with early hair loss have slightly worse blood sugar and fat levels, suggesting possible health risks and need for monitoring.

Finasteride safely treats hair loss without harming hormones or reproduction, but may slightly reduce sexual function.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

Early balding in men might be a male hormonal equivalent of polycystic ovaries syndrome in women.

The girl's unexpected pubic hair growth led to a diagnosis different from complete androgen insensitivity syndrome.

PCOS is a condition causing irregular periods, excess male hormones, and infertility, often managed by targeting insulin resistance and specific symptoms.

Mutations in the androgen receptor gene cause Androgen Insensitivity Syndrome, affecting sexual development.

Monascus helps prevent baldness, prostate issues, and may be a natural alternative to medications.

Hair loss may indicate higher heart risk and metabolic issues.

The document does not determine if adults with aphallia are fertile.

PCOS is a complex condition with major health impacts, needing more research for better diagnosis and treatment.

Polycystic Ovary Syndrome (PCOS) is a common condition in women that can cause metabolic, reproductive, and psychological issues, and requires lifestyle changes and medication for management.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

New compounds show promise for treating hair loss, enlarged prostate, and prostate cancer, with some being more effective and having different side effects than current treatments.

Mouflon rams mature gradually with changes in body, horns, and hormones linked to age and seasons, reaching full sexual maturity well after puberty.

DHT in the human prostate is produced through multiple pathways, not just from testosterone.

Inhibitors of the enzyme 5 alpha-reductase could potentially treat disorders like prostate cancer and baldness.

The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.

Genes and hormones cause hair loss, with four genes contributing equally.

Pattern baldness is likely caused by a dominant gene influenced by testosterone levels, making it more common in men.

Men with severe hair loss may have poorer sperm quality.

Two new mutations in the AR gene linked to severe androgen insensitivity were found.

Testosterone replacement therapy helps manage deficiency and has various methods, but requires careful monitoring to avoid side effects.

Three siblings with a rare genetic condition had abnormal sexual development and chose different gender identities, needing surgery and therapy.