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The LRRK2-G2019S mutation in Parkinson's disease has a lifetime penetrance of 25-35%, and finasteride may help reduce symptoms in adult male Tourette syndrome patients.

RSPO1 mutations in certain patients lead to skin cells that don't develop properly and are more likely to become invasive, increasing the risk of skin cancer.

Skin problems in PCOS, like excess hair, acne, and hair loss, may not always indicate high male hormone levels and need careful diagnosis for proper treatment.

Managing emotional distress, obesity, insulin resistance, and high male hormones is crucial for improving well-being in women with PCOS.

A high-fat diet caused severe health problems in female macaques but was reversible with a normal diet, while male macaques reacted differently.

Some plant-based treatments may help with ovary function, insulin resistance, and excess male hormones in PCOS, but more research is needed to confirm their safety and effectiveness.

Researchers identified genes in scalp hair follicles that may affect hair traits and hair loss.

MendelVar is a tool that helps identify important genes by combining GWAS data with Mendelian disease information.

Hair health is influenced by genetics, aging, and environmental factors, with proper care needed to maintain it.

Genetic defects in androgen production are linked to male developmental disorders and are improving treatment understanding.

Testosterone therapy is generally safe for transmen, improves sexual function, and has manageable health risks with proper monitoring.

Insulin resistance and high male hormone levels are major causes of Polycystic Ovary Syndrome.

Male mice are more susceptible to autism-like changes from valproic acid than female mice.

Men with early balding may have hormonal imbalances similar to women with PCOS and could benefit from similar treatments.

The document concludes that hair loss is complex, affects many people, has limited treatments, and requires more research on its causes and psychological impact.

A woman's severe hormone imbalance after menopause led to finding a rare ovarian tumor, treated by surgery.

Finasteride can have lasting negative effects on brain function and behavior by disrupting neurosteroid production.

Mutations in the androgen receptor gene cause different levels of androgen insensitivity, making it hard to create simple tests for the condition.

The research found that genetic factors for male pattern baldness in African men differ significantly from those in Europeans.

The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.

Masculine facial features may not reliably indicate heritable health, and more research is needed.

Scientists turned rat thymus cells into stem cells that can help repair skin and hair.

Versican, a protein, is less present in thinning hair follicles and this decrease might contribute to common hair loss in men.

Cholesterol sulfate buildup due to a genetic mutation disrupts the skin barrier, leading to the scaling skin seen in X-linked ichthyosis.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

The length of the CAG repeat in the androgen receptor gene affects the risk and progression of prostate cancer, BPH, infertility, and undermasculinized genitalia.

Hair diversity is influenced by complex genetics and environmental factors, requiring more research for practical solutions.

Finger length ratios are not linked to the number of specific gene repeats affecting testosterone sensitivity.

Female hair loss linked to metabolic syndrome, not in males.