5 citations,
January 1985 in “Archives of Dermatology” Skin creams that block male hormones may help with hair growth, hair loss, and acne.
December 2022 in “International Journal of Health Science” High levels of male hormones in women with PCOS can lead to fertility issues and symptoms like irregular periods, hair growth, acne, and hair loss; lifestyle changes are recommended for management.
947 citations,
February 2004 in “The Journal of Clinical Endocrinology and Metabolism” Most women with excess male hormones have Polycystic Ovary Syndrome, and hormonal therapy can improve symptoms but may cause side effects.
209 citations,
March 1998 in “Biochemical and biophysical research communications” Scientists found new nonsteroidal compounds that can act like natural male hormones and might help treat male fertility and hormone issues.
195 citations,
November 2019 in “Clinica Chimica Acta” High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.
21 citations,
July 2019 in “Cardiovascular Research” High levels of male hormones in pregnant mice cause heart enlargement and poor heart function in their female babies.
19 citations,
January 2017 in “Hormone Molecular Biology and Clinical Investigation” High levels of male hormones are very common in women with PCOS and affect their metabolism differently depending on their weight.
14 citations,
January 2008 in “Gynecological Endocrinology” High levels of male hormones in women without tumors are linked to metabolic problems and can be treated with metformin.
9 citations,
January 2022 in “Reproductive Biology and Endocrinology” High levels of male hormones and irregular periods best predict how well PCOS patients will respond to metformin treatment.
2 citations,
September 2008 in “Fertility and Sterility” Clinical signs of excess male hormones and actual hormone levels in the blood do not always match in women with polycystic ovary syndrome.
December 2022 in “CRC Press eBooks” Antiandrogens block male hormones and are not safe during pregnancy.
43 citations,
May 1988 in “British Journal of Dermatology” Patients with acanthosis nigricans often have insulin resistance and signs of increased male hormones, but treatment targeting these male hormones is generally ineffective.
March 1998 in “Journal of dermatological science” Protease Nexin-1 is found in human hair growth cells and is affected by male hormones.
67 citations,
February 2010 in “Acta Obstetricia et Gynecologica Scandinavica” Hirsutism is a strong sign of high male hormones and metabolic problems in women with PCOS, but acne and hair loss are not.
27 citations,
September 1999 in “Journal of Investigative Dermatology” Human skin cells contain Protease Nexin-1, and male hormones can decrease its levels, potentially affecting hair growth.
20 citations,
January 2019 in “Frontiers of Hormone Research” The book explains how excess male hormones can affect various conditions like Polycystic Ovary Syndrome and Cushing's disease.
18 citations,
July 2020 in “Basic and Clinical Andrology” Wait 3 months after COVID-19 before trying assisted reproduction and further research is needed on COVID-19's effects on male hormones and fertility.
6 citations,
April 2004 in “Journal of Enzyme Inhibition and Medicinal Chemistry” New progesterone-based compounds can block male hormones.
2 citations,
April 2023 in “BMC endocrine disorders” The link between physical signs of high male hormones and hormone levels in women with PCOS changes with age.
Benign ovarian tumors can cause excess male hormones and related conditions in postmenopausal women.
November 2022 in “Journal of the Endocrine Society” A 13-year-old girl's masculine symptoms improved after surgery for a rare adrenal tumor that produced male hormones.
December 2020 in “Research Square (Research Square)” Rare ovarian tumors can cause increased male hormones in postmenopausal women; surgery is an effective treatment.
January 2020 in “Medical journal of Dr. D.Y. Patil Vidyapeeth” Indian women with skin signs of high male hormones often have related health issues.
November 2004 in “Medical Journal of Indonesia” Hormonal imbalances can cause skin and hair problems in women, and treatments that block male hormones can help.
8 citations,
May 1996 in “Endocrinology” Certain adrenal hormones can strongly stimulate oil gland growth in hamster skin, similar to male hormones.
1540 citations,
October 2008 in “Fertility and Sterility” The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.
150 citations,
November 2007 in “The Journal of Clinical Endocrinology and Metabolism” About 2.2% of women with symptoms of high male hormones have a mild form of congenital adrenal hyperplasia, and measuring a specific hormone level can accurately diagnose it.
118 citations,
February 2009 in “Fertility and Sterility” Most women with PCOS have high levels of male hormones, and free testosterone is the best marker for this.
76 citations,
November 1997 in “The American journal of psychiatry” Some autistic children may have higher levels of male hormones, which could be linked to aggression.
70 citations,
February 2012 in “Human Reproduction” Many young women who donate blood have hormonal disorders like excess male hormones and PCOS.