403 citations,
November 2005 in “Journal of Endocrinology” Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.
77 citations,
May 2012 in “Expert Opinion on Emerging Drugs” New treatments for male hypogonadism are effective and should be personalized.
36 citations,
October 2016 in “Bone” A male with aromatase deficiency improved bone health with estradiol treatment.
47 citations,
August 2000 in “Endocrine Reviews” The document concludes that more research is needed to understand excessive hair growth in women with normal hormone levels and regular ovulation.
15 citations,
August 2016 in “Current Urology Reports” Nandrolone and oxandrolone could help treat male health issues like muscle loss and low testosterone.
4 citations,
May 2013 in “Actas Dermo-Sifiliográficas” Most Spanish Caucasian women have a widow's peak, and their hormone levels suggest they process certain hormones faster.
110 citations,
April 2002 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” Dihydrotestosterone gel improved well-being and sexual function in older men without negatively affecting prostate health.
38 citations,
January 1997 in “Gynecological Endocrinology” Finasteride and flutamide effectively reduce hirsutism in PCOS women, with flutamide also lowering hormone levels.
4 citations,
August 2016 in “Australasian Journal of Dermatology” Hair loss is linked to insulin resistance in women, regardless of hormone levels.
1 citations,
May 2017 in “InTech eBooks” Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.
56 citations,
August 2005 in “Journal of Investigative Dermatology Symposium Proceedings” Different women's hair and skin glands respond to hormones in varied ways, which can cause unwanted hair growth even with normal hormone levels, and more research is needed to treat this effectively.
38 citations,
February 2005 in “The journal of sexual medicine” The testosterone patch and gel are both effective, but they have different absorption patterns and effects on hormone levels.
10 citations,
December 2017 in “Chemosphere” Bisphenol-A (BPA) increases connections between brain cells and boosts their activity, but it blocks the effects of a male hormone on brain cell plasticity.
75 citations,
May 1986 in “Clinics in endocrinology and metabolism” Male hormones are important for hair and oil gland development and can cause conditions like excessive hair growth and acne.
43 citations,
May 1988 in “British Journal of Dermatology” Patients with acanthosis nigricans often have insulin resistance and signs of increased male hormones, but treatment targeting these male hormones is generally ineffective.
14 citations,
September 1986 in “Archives of Dermatology” Women with low SHBG levels and a high 3a-diol G to SHBG ratio are likely to experience female pattern baldness, possibly due to a slight excess of androgens affecting sensitive hair bulbs.
9 citations,
June 2014 in “European Journal of Obstetrics & Gynecology and Reproductive Biology” Blood AMH levels are higher in women with PCOS than in those with other similar conditions.
29 citations,
February 2004 in “Experimental and Clinical Endocrinology & Diabetes” Men with early balding often have hormone levels similar to women with polycystic ovary syndrome.
17 citations,
February 2020 in “Journal of Pediatric and Adolescent Gynecology” Early medical support for transgender youth is important for their health, with low regret for gender-affirming hormone use and a need for knowledgeable care providers.
5 citations,
June 2021 in “Pharmacological Reports” Vitamin D may help reduce antibody levels in men with autoimmune thyroiditis and early-onset androgenic alopecia, but has no significant impact on thyroid function.
1 citations,
January 2021 in “Acta dermatovenerologica Alpina, Pannonica et Adriatica (Tiskana izd.)” High prolactin levels might be linked to hair loss in autoimmune thyroid disease, but more research is needed.
April 2023 in “Clinical Chemistry and Laboratory Medicine” The document concludes that inflammation markers can be used in diabetes, vitamin D3 affects immune pathways, hyperthyroidism changes hormone levels, androgen levels help diagnose Adrenocortical Carcinoma, erectile dysfunction is linked to diabetes, hypogonadism is common in HIV-infected males, and hormones can be biomarkers for various conditions.
January 2017 in “Springer eBooks” Understanding genes and hormones is crucial for managing male puberty and sex development disorders.
May 2022 in “The Journal of Clinical Pharmacology” Metformin reduces certain hormone levels in men with early-onset hair loss.
9 citations,
April 2018 in “Biology of reproduction” Diet changes hormone levels in pregnant ewes by affecting metabolism, not placental synthesis.
3 citations,
January 1994 in “Toxicological Sciences” Finasteride causes abnormal growth in male mice cells at high doses.
1 citations,
December 1992 in “International Journal of Dermatology” No significant hormone differences found in postmenopausal women with androgenetic alopecia.
August 2021 in “Clinical and Experimental Dermatology” Children under 10 can experience hair thinning without hormone issues, and it may improve with treatment.
June 1995 in “International Journal of Gynecology & Obstetrics” Women with hair loss have higher androgen levels, while men with early balding have altered androgen ratios.
227 citations,
January 1998 in “Journal of Endocrinology” Cells from balding scalps have more androgen receptors than cells from non-balding scalps.