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Steroid Sulfatase inhibitors show promise in treating hormone-dependent disorders like cancers, hair loss, and acne, with 667COUMATE being a potential candidate for breast cancer treatment trials.

Male hormones indirectly affect skin cell development by increasing growth factor levels from skin fibroblasts.

Some skin medications can harm male fertility, but they don't seem to cause birth defects from father's exposure.

Finasteride effectively treats enlarged prostate and male baldness, improves symptoms of hirsutism in women, but doesn't work for acne, and may delay prostate cancer progression with few side effects.

A young man with an eating disorder had a life-threatening adrenal crisis due to an autoimmune condition, highlighting the need for better education on managing hormone treatments.

Hormone therapy in transgender women can affect hair growth and acne, and there are specific skin issues related to gender-affirming surgery, but more research is needed on their dermatological health.

Male hormones control a specific gene in hamster skin, with different hormones having varying effects.

COVID-19 may affect male fertility and women might have better outcomes due to hormonal and immune differences.

A woman's male-like symptoms and high testosterone were due to ovarian hilus-cell hyperplasia, which improved after surgery.

Male tissue has more cell death than female tissue after ischemia, and some neurosteroids only protect female cells.

MK-386 and finasteride together effectively reduce DHT levels, potentially treating acne and male pattern baldness.

The document concludes that gender-affirming treatments are essential for transgender individuals and outlines safe hormone therapy practices.

High uric acid levels link to male pattern baldness, especially in young men.

Pre-operative hormone treatment for hypospadias surgery might improve outcomes, but more research is needed to confirm.

Hormone imbalances from the pituitary, thyroid, and adrenal glands can cause infertility, but treating these disorders can improve fertility.

Women with PCOS have higher oxidative stress and hormone imbalances, suggesting managing oxidative stress could help.

Effective acne management in PCOS includes hormone therapy, metformin, isotretinoin, weight loss, diet, exercise, and personalized treatment plans.

Evening primrose oil significantly improves hormone levels and reduces BMI and cholesterol in women with PCOS.

A 24-year-old woman had a rare ovarian tumor that caused male-pattern hair growth and was hard to diagnose and treat.

Parthenolide promotes hair growth in mice and may influence pathways related to male pattern baldness.

The document concludes that skin aging in women can be caused by UV exposure and hormonal changes, and treatments like hormone replacement therapy and various skin therapies can help.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

Estrogen loss during menopause worsens skin health, but hormone replacement therapy may improve it, though more research is needed.

Hormones significantly affect hair and oil gland function in the skin, and more research is needed on skin-related hormone disorders.

Genetic marker rs12558842 strongly linked to male hair loss.

DHEA may help with sexual function when used intravaginally by menopausal women but is similar to hormone therapy in other aspects and might cause more side effects like acne and hair loss.

High levels of male hormones in pregnant mice cause heart enlargement and poor heart function in their female babies.

The activity of a specific rat enzyme in the prostate and epididymis is highly dependent on the acidity level.

Drugs for hormone-related conditions might help treat mental disorders but could have serious side effects.

Both treatments reduced excessive hair growth in PCOS, but there was no difference in weight, hair score, hormone levels, or insulin resistance.