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GlossaryAndrogenetic Alopecia (Male Hair Loss)

genetic hair loss influenced by androgens, often hereditary

Androgenetic Alopecia, commonly known as Male Pattern Baldness or Female Pattern Baldness, is a genetic condition characterized by progressive hair thinning and loss. It is influenced by androgens (male hormones) and typically follows a recognizable pattern, such as a receding hairline in men and diffuse thinning on the crown in women. This condition is the most common cause of hair loss, affecting both genders, and is often hereditary.

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Assessment of the Efficacy and Tolerability of a Topical Formulation Containing Caffeine and Procapil 3% for Improvement of Male Pattern Hair Loss

research Assessment of the Efficacy and Tolerability of a Topical Formulation Containing Caffeine and Procapil 3% for Improvement of Male Pattern Hair Loss

November 2023 in “Journal of Cosmetic Dermatology”

The topical treatment with caffeine and Procapil 3% improved male pattern hair loss and was well tolerated after 12 weeks.

research Male Experiences of Hair Removal and Loss: Depilation Practices and Motivations

April 2016 in “Journal of Aesthetic Nursing”

Men are increasingly removing body hair for looks and cleanliness, and while hair loss can cause distress, it doesn't affect their self-esteem as much as it does in women.

research Prevalence of Male and Female Pattern Hair Loss in Maryborough

193 citations, August 2005 in “Journal of Investigative Dermatology Symposium Proceedings”

Hair loss common in Australia; men affected earlier, more often than Asians; women less concerned.

Efficacy, Safety, and Tolerability of Dutasteride 0.5 mg Once Daily in Male Patients with Male Pattern Hair Loss: A Randomized, Double-Blind, Placebo-Controlled, Phase III Study

research Efficacy, Safety, and Tolerability of Dutasteride 0.5 mg Once Daily in Male Patients with Male Pattern Hair Loss: A Randomized, Double-Blind, Placebo-Controlled, Phase III Study

92 citations, June 2010 in “Journal of The American Academy of Dermatology”

Dutasteride 0.5 mg daily improves hair growth safely in men with hair loss.

A Pilot Split-Scalp Study of Combined Fractional Radiofrequency Microneedling and 5% Topical Minoxidil in Treating Male Pattern Hair Loss

research A Pilot Split-Scalp Study of Combined Fractional Radiofrequency Microneedling and 5% Topical Minoxidil in Treating Male Pattern Hair Loss

25 citations, June 2018 in “Clinical and Experimental Dermatology”

Combined microneedling and minoxidil improves hair growth more than minoxidil alone.

research Hormonal Parameters in Androgenetic Hair Loss in Males

21 citations, January 1991 in “Dermatology”

Men with male pattern hair loss have different levels of certain hormones compared to men without hair loss.

Efficacy and Safety of 3% Minoxidil Versus Combined 3% Minoxidil / 0.1% Finasteride in Male Pattern Hair Loss: A Randomized, Double-Blind, Comparative Study

research Efficacy and Safety of 3% Minoxidil Versus Combined 3% Minoxidil / 0.1% Finasteride in Male Pattern Hair Loss: A Randomized, Double-Blind, Comparative Study

6 citations, October 2012 in “PubMed”

The combined treatment of 3% minoxidil and 0.1% finasteride is more effective in improving hair loss than 3% minoxidil alone, with similar side effects.

research The Adapted Classification of Male Pattern Hair Loss Improves Reliability

5 citations, January 2012 in “Dermatology”

Adapted classification better assesses male pattern hair loss and its link to heart disease.

research Efficacy and Safety of 5% Minoxidil Topical Foam in Male Pattern Hair Loss Treatment and Patient Satisfaction

4 citations, January 2016 in “Acta dermatovenerologica Alpina, Pannonica et Adriatica (Tiskana izd.)”

5% minoxidil foam is a safe, effective treatment for male pattern hair loss, with increased hair count and few side effects.

research SNP Variation in Male Pattern Hair Loss in Russians with Different Dihydrotestosterone Levels

3 citations, December 2018 in “Meta Gene”

Certain gene variations increase male hair loss risk, influenced by hormone levels.

research Short Anagen Hair Syndrome Is Caused by Mutations in the WNT10A Gene and Has a Genetic Overlap With Male Pattern Hair Loss

November 2023 in “British Journal of Dermatology”

Mutations in the WNT10A gene cause Short Anagen Hair syndrome and increase the risk of male pattern hair loss.

research Efficacy of Topical Minoxidil and Oral Spironolactone Versus Minoxidil and Finasteride in Androgenic Alopecia

August 2023 in “Journal of Cosmetic Dermatology”

Both minoxidil-spironolactone and minoxidil-finasteride treatments work for hair loss, but minoxidil-spironolactone is slightly more effective, especially in women.

research How His Hair Is Growing Thin: On the Emotional Significance of Male Pattern Hair Loss

April 2023 in “Journal of the American Psychoanalytic Association”

Male pattern hair loss can cause significant emotional distress for men.

research Efficacy and Safety of Scalp Microneedling in Male Pattern Hair Loss

October 2022 in “Skin appendage disorders”

Scalp microneedling did not improve hair coverage or density in male pattern hair loss.

How to Deal with the Issues of Fertility, Malignancies, and Postfinasteride Syndrome While Prescribing Finasteride for Male Pattern Hair Loss

research How to Deal with the Issues of Fertility, Malignancies, and Postfinasteride Syndrome While Prescribing Finasteride for Male Pattern Hair Loss

January 2022 in “Skin appendage disorders”

Finasteride is effective for male hair loss, but it may cause fertility issues, mental health problems, and rarely, breast growth. Regular health checks can reduce the risk of prostate cancer. Patient understanding and involvement in treatment is important.

research Clinical Use of Extracellular Vesicles in the Management of Male and Female Pattern Hair Loss: A Preliminary Retrospective Institutional Review Board Safety and Efficacy Study

January 2022 in “Aesthetic surgery journal”

Extracellular vesicles may effectively treat hair loss with minimal side effects.

Faculty Opinions Recommendation of Persistent Sexual Dysfunction and Depression in Finasteride Users for Male Pattern Hair Loss: A Serious Concern or Red Herring?

research Faculty Opinions Recommendation of Persistent Sexual Dysfunction and Depression in Finasteride Users for Male Pattern Hair Loss: A Serious Concern or Red Herring?

December 2015 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”

Finasteride, a hair loss treatment, may cause long-term sexual dysfunction and depression.

research Genetic Differences Between Male and Female Pattern Hair Loss in a Korean Population

July 2024 in “Life”

Certain genes may influence hair loss differently in men and women.

research Management of Male Pattern Hair Loss

3 citations, July 2001 in “PubMed”

Finasteride helps manage male hair loss, but realistic expectations and support are crucial.

research Pathogenesis and Classification of Male Pattern Hair Loss (Androgenic Alopecia)

October 2022 in “Hair Transplantation”

research Surgical and Medical Treatment for Male Pattern Hair Loss

May 2004 in “CRC Press eBooks”

research Efficacy of 5% Minoxidil Versus Combined 5% Minoxidil and 0.01% Tretinoin for Male Pattern Hair Loss

43 citations, January 2007 in “American Journal of Clinical Dermatology”

Combined minoxidil and tretinoin solution works as well as regular minoxidil for male hair loss.

research Clinical Dose Ranging Studies with Finasteride, a Type 2 5α-Reductase Inhibitor, in Men with Male Pattern Hair Loss

5 citations, October 1999 in “Journal of The American Academy of Dermatology”

research Male Androgenetic Alopecia Is Due to Hair Follicle Stem Cell Inactivation

3 citations, April 2011 in “Expert Review of Dermatology”

Male hair loss is caused by inactive hair follicle stem cells.

research Management of Hair Loss

74 citations, April 2005 in “Dermatologic Clinics”

Minoxidil and finasteride are effective for male hair loss, minoxidil for female hair loss, and various treatments like corticosteroids work for alopecia areata; treatment should be tailored to the individual.