research Sebocytes Are the Key Regulators of Androgen Homeostasis in Human Skin
Sebocytes play a key role in controlling androgen levels in human skin.
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research Biology of Estrogens in Skin: Implications for Skin Aging
Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.
research Bioengineering a 3D Integumentary Organ System from iPS Cells Using an In Vivo Transplantation Model
Researchers created a fully functional, bioengineered skin system with hair from stem cells that successfully integrated when transplanted into mice.
research Dermatologic Care for Lesbian, Gay, Bisexual, and Transgender Persons
LGBT individuals have unique skin health needs, including higher STD risks and side effects from gender-affirming treatments, requiring dermatologists to offer knowledgeable and culturally competent care.
research Hirsutism: Evaluation and Treatment
Excessive hair growth can be assessed by history, exam, and blood tests, and treated with medication like dexamethasone, birth control pills, and spironolactone.
research Conversion of the Nipple to Hair-Bearing Epithelia by Lowering Bone Morphogenetic Protein Pathway Activity at the Dermal-Epidermal Interface
Blocking a specific protein signal can make hair grow on mouse nipples.
research Basics of Androgen Synthesis and Action
Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.
research Side Effects of 5-Alpha Reductase Inhibitors: A Comprehensive Review
5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.
research Nonclassic Congenital Adrenal Hyperplasia: Pathophysiology, Genetics, and Management
Nonclassic congenital adrenal hyperplasia is a genetic disorder causing hormone imbalances, affecting fertility and requiring personalized treatment.
research The Basic Science of Hair Biology
Hair disorders are caused by a complex mix of biology, genetics, hormones, and environmental factors, affecting hair growth and leading to conditions like alopecia.
research Inhibitory Activities of Some Traditional Chinese Herbs Against Testosterone 5α-Reductase and Effects of Cacumen Platycladi on Hair Regrowth in Testosterone-Treated Mice
Certain Chinese herbs, especially Cacumen platycladi, can promote hair regrowth and reduce hair loss-related hormone levels in mice.
research Distinct Mechanisms Underlie Pattern Formation in the Skin and Skin Appendages
Different processes create patterns in skin and things like hair and feathers.
research Is Polycystic Ovary Syndrome a Sexual Conflict? A Review
The conclusion suggests that PCOS may persist due to genetic traits that, while harmful for female fertility, could have provided survival and reproductive benefits to males.
research Women's Health Care During the Perimenopause
The document concludes that low-dose oral contraceptives and hormonal therapies can manage perimenopause symptoms and reduce some health risks, but lifestyle changes and disease screening are also important.
research Candidate SNP Markers of Reproductive Potential Predicted by Significant Change in Affinity of TATA-Binding Protein for Human Gene Promoters
Certain genetic markers linked to reproductive potential were identified by their impact on a protein's ability to bind to genes.
research A New Label-Free Screen for Steroid 5α-Reductase Inhibitors Using LC-MS
Researchers developed a new method to find substances in herbs that can block a specific enzyme linked to hair loss.
research Relationship Between Helicobacter Pylori Infection and Vitiligo: A Prospective Study
People with vitiligo may have a higher rate of Helicobacter pylori infection, but the infection's severity doesn't affect how severe the vitiligo is.
research A Functional Polymorphism in Interleukin-1α (IL1A) Gene Is Associated with Risk of Alopecia Areata in Chinese Populations
A certain genetic variation in the IL1A gene may lower the risk of a hair loss condition in Chinese people.
research Changes in Hydrophobic Proteins in Response to Biotin Administration in Serum of Infant Patients with Alopecia as Assessed by the Protein Micro-Sequencing Method
Biotin helps regulate proteins in the blood, which may explain its role in hair growth.
research Incidence of Virilization in Sex Cord Stromal Tumors of Ovary: A 5-Year Experience in a Tertiary Care Gynecological Center
Some ovarian tumors can cause masculinization, and it's important to check for various causes when this symptom is present.
research Hair Cortisol in Polycystic Ovary Syndrome
Women with PCOS have higher hair cortisol levels, which are linked to worse metabolic and inflammatory conditions.
research The Role of Versican in the Skin Extracellular Matrix and Its Interaction with Hyaluronic Acid
Hyaluronic acid and versican are important for skin healing and hair growth and might help in regenerative medicine.
research Characterization of Novel TMEM173 Mutation with Additive IFIH1 Risk Allele
A new mutation in the TMEM173 gene and a risk allele in IFIH1 cause a unique set of immune-related symptoms.
research Hair Physiology: Hair Growth, Alopecia, Scalp Treatment, Etc.
The document concludes that new treatments for hair loss may involve a combination of cosmetics, clinical methods, and genetic approaches.
research Finding Long-COVID: Temporal Topic Modeling of Electronic Health Records from the N3C and RECOVER Programs
Long-COVID has diverse, long-term health impacts, especially in young people.
research Tackling Underrepresentation to Aid Understanding of Parkinson’s Disease: Progress and Further Opportunities
Addressing underrepresentation in Parkinson's research is crucial for better treatments and understanding.
research The Story of When Kidneys Fail and the Contribution of Air Vice-Marshal Sir Ralph Jackson
Air Vice-Marshal Sir Ralph Jackson significantly advanced dialysis technology in the UK.
research Polycystic Ovary Syndrome: Anogenital Distance as a Marker of Prenatal Androgenic Environment and Review and Comparison of Diagnostic Criteria
Longer anogenital distance may indicate a higher chance of having polycystic ovary syndrome, and measuring this distance along with hormone levels could improve diagnosis.
research Effect of Decellularisation Methods on Methacryloyl-Substituted Placental ECM Hydrogels
PlacMA hydrogels from human placenta are versatile and useful for cell culture and tissue engineering.
research Mechanism of Action of Avicennia Marina Heartwood Extract and Avicequinone C on Human Dermal Papilla Cells Isolated from Androgenic Alopecia Patients
Avicennia Marina extract and avicequinone C can reduce hair loss hormone production and increase hair growth factors, suggesting they could be used to treat androgenic alopecia.