7 citations
,
January 2016 in “British Journal of Cancer” This study found that certain male pattern baldness subtypes at age 45 are associated with an increased risk of developing colorectal neoplasia.
7 citations
,
December 2014 in “Journal of dermatology” This study found that miR-221 levels in hair shafts were significantly higher in malignant melanoma patients compared to controls, suggesting potential as a non-invasive screening marker.
7 citations
,
September 2014 in “European Journal of Dermatology” This study found a significant positive correlation between hair thickness and growth rate, with a notably slower growth rate observed in men with male pattern hair loss compared to healthy controls.
7 citations
,
January 2014 in “Rinshō shinkeigaku” This report describes two cases of stroke associated with finasteride use for male-pattern hair loss, suggesting a potential link to thrombosis due to increased estrone and estradiol levels.
7 citations
,
September 2006 in “Molecular Carcinogenesis” This study observed that K5Cre +/+ transgenic mice develop a distinct phenotype characterized by wavy hair, curly whiskers, and an increased rate of papilloma malignant transformation.
7 citations
,
September 2004 in “대한의생명과학회지” This study suggests that a topical oriental medicine extract may improve hair density and scalp condition in individuals experiencing male pattern hair loss after 18 months of use.
7 citations
,
November 1987 in “Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy” This article reviews the potential of topical minoxidil to cosmetically thicken hair in some individuals with male pattern hair loss, but it reports no new clinical results.
7 citations
,
January 1976 in “International Journal of Environmental Studies” This study found that applying a mix of cholesterol and Tween 60 detergent to mouse skin significantly reduced epidermal cell mitotic activity.
6 citations
,
May 2006 in “Skinmed” This article reviews the classification history of androgenic alopecia and highlights the need for further research to find effective hair growth medications.
6 citations
,
June 2021 in “Journal of health psychology” This review found that commercial influences may affect how male baldness is represented as a disease and how treatment options are presented, often omitting limitations.
6 citations
,
January 2021 in “International Journal of Molecular Sciences” This study suggests that finasteride treatment in male rats can lead to changes in liver carbohydrate metabolism and may result in metabolic disruptions and liver steatosis in their offspring.
6 citations
,
November 2020 in “Chinese Medical Journal” This study found that among Chinese males with male androgenic alopecia, combination therapy using topical minoxidil and nano-microneedle-assisted fibroblast growth factor significantly improved hair density, diameter, and follicular unit density over 16 weeks, outperforming individual treatments.
6 citations
,
September 2020 in “Journal of The American Academy of Dermatology” This letter discusses how severe baldness in men is associated with higher risk of severe COVID-19, and highlights research suggesting antiandrogen medications may improve outcomes.
6 citations
,
June 2019 in “Skin Research and Technology” In this study, finasteride treatment for two years did not significantly reverse miniaturized hair follicles in men with male pattern hair loss, challenging the "reversal hypothesis" as 79 out of 113 miniaturized hairs remained unchanged.
6 citations
,
October 2012 in “PubMed” This study found that while the combination therapy of 3% minoxidil and 0.1% finasteride lotion showed greater improvement in global photographic assessments for androgenetic alopecia, hair counts did not differ significantly from minoxidil alone.
6 citations
,
April 2004 in “Dermatologic Surgery” This study found that 32% of men continued finasteride use for 1 to 3 years, with many reporting poor hair growth results.
6 citations
,
January 2003 in “Dermatology” This study reviewed 26 cases of X-linked recessive ichthyosis and observed 11 patients with advanced-stage androgenetic alopecia, suggesting a compensatory role of two steroid biosynthesis pathways.
6 citations
,
August 2001 in “PubMed” This review discusses the suitability of stump-tailed macaques and rodent models for studying hair growth and developing treatments for androgenetic alopecia, but reports no new experimental results.
6 citations
,
October 2000 in “International Journal of Dermatology” This article discusses the importance of focusing on prevention rather than regrowth in managing male pattern hair loss but reports no new clinical results.
5 citations
,
January 2013 in “Journal der Deutschen Dermatologischen Gesellschaft” The document concludes that individualized treatment for malignant epithelial tumors is necessary and more research on metastatic squamous cell carcinoma treatments is needed.
5 citations
,
July 2000 in “Southern Medical Journal” This review discusses available treatments for androgenetic alopecia in men, like finasteride and 5% minoxidil, and notes that hair growth results are unpredictable and often driven by industry-sponsored studies.
5 citations
,
May 2022 in “Diagnostics” This study found that certain lncRNA gene polymorphisms in HOTAIR and MALAT1 are associated with increased susceptibility to systemic lupus erythematosus, potentially informing clinical applications.
5 citations
,
August 2021 in “Journal of The European Academy of Dermatology and Venereology” In this phase 1B clinical trial, sublingual minoxidil was tested for its effects on male and female pattern hair loss in a randomized, double-blind, placebo-controlled setting, but the abstract does not provide specific results or conclusions.
5 citations
,
January 2021 in “Journal of Cosmetic Dermatology” This study found that topical cetirizine treatment significantly improved hair regrowth and patient satisfaction in male patients with androgenetic alopecia compared to a placebo, highlighting its potential role in treatment.
5 citations
,
November 2020 in “JAMA Dermatology” Finasteride may cause side effects; more research needed.
5 citations
,
January 2020 in “Skin Research and Technology” This study reported that combined oral finasteride and topical 5% minoxidil treatment in men with male-pattern hair loss improved hair growth by initiating anagen in pre-existing but deficient follicles, yet the growth rates remained unchanged and did not normalize hair productivity.
5 citations
,
January 2020 in “International Journal of Trichology” This study found that both microneedling and microneedling with platelet-rich plasma improved hair thickness and density in male pattern alopecia, but no additional benefit was observed with the addition of platelet-rich plasma.
5 citations
,
August 2018 in “International Journal of Dermatology” This study suggests obstructive sleep apnea may increase the risk of male-pattern baldness in men with a family history of hair loss, and links low serum transferrin saturation levels to both conditions.
5 citations
,
March 2017 in “Journal of Dermatology” This survey reported that 37.6% of male AGA patients were satisfied with their treatments, with the highest satisfaction for 5-alpha-reductase inhibitors, and revealed differing perceptions between physicians and patients about AGA's impact on confidence and treatment involvement.
5 citations
,
August 2016 in “bioRxiv (Cold Spring Harbor Laboratory)” In this study, researchers identified over 250 new genetic loci linked to severe male pattern baldness, and developed a prediction algorithm that could accurately differentiate between those with severe and no hair loss.