research Birth, Life, and Death of the MAGE3 Hypothesis of Alopecia Areata Pathobiology
The MAGE3 hypothesis for alopecia areata did not lead to a significant breakthrough.
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540-570 / 1000+ resultsresearch Alopecia Areata: Autoimmune Nature, Genetic Associations, and Treatments
Alopecia areata is an autoimmune disease with genetic links, treatable with certain medications, and can affect mental health.
research Updates in the Pathogenesis of Alopecia Areata
Alopecia areata is an autoimmune condition causing hair loss, linked to genetic factors and immune system issues, with no cure yet.
research Psoriasis
Psoriasis treatments range from topical creams to systemic medications with serious side effects, and while treatments can manage symptoms, there is no cure.
research HLA-B27 Antigen in Women With Ankylosing Spondylitis
Most women with ankylosing spondylitis tested positive for HLA-B27, suggesting it's useful for diagnosis.
research Can Gut Flora Changes Be New Biomarkers for Depression?
Gut flora changes could potentially indicate depression, but more research is needed.
research Major Improvement in Wound Healing Through Pharmacologic Mobilization of Stem Cells in Severely Diabetic Rats
A new therapy sped up wound healing and reduced scarring in diabetic rats.
research Use of Chemotherapy During Human Pregnancy
Chemotherapy in the first trimester of pregnancy is risky, but in the second and third trimesters, it's generally safe with careful drug selection and timing.
research Integrated Safety Analysis of Baricitinib in Adults With Severe Alopecia Areata From Two Randomized Clinical Trials
Baricitinib for severe alopecia areata is generally safe, with common side effects like infections and acne, and low rates of serious complications.
research The Associated Burden of Mental Health Conditions in Alopecia Areata: A Population-Based Study in UK Primary Care
People with alopecia areata have a higher risk of depression and anxiety, and often face unemployment and work absences.
research Integrated Safety Analysis of Ritlecitinib, an Oral JAK3/TEC Family Kinase Inhibitor, for the Treatment of Alopecia Areata from the ALLEGRO Clinical Trial Program
Ritlecitinib is safe and well-tolerated for treating alopecia areata in patients aged 12 and older.
research Baricitinib Safety for Events of Special Interest in Populations at Risk: Analysis from Randomised Trial Data Across Rheumatologic and Dermatologic Indications
Baricitinib, a drug for rheumatoid arthritis, atopic dermatitis, and alopecia areata, is generally safe with low risk of major side effects, even in patients with risk factors. It's also effective in promoting hair regrowth in alopecia areata patients.
research Major Differences in Expression of Inflammatory Pathways in Skin from Different Body Sites of Healthy Individuals
Different parts of the body have unique immune characteristics in their skin.
research Major Improvement of Very Severe Alopecia Areata in Patients Treated With the Combination of Baricitinib and Low Doses of Corticosteroids: An Eight-Case Series
Combining baricitinib with low-dose corticosteroids significantly improved severe hair loss in eight patients.
research Bidirectional Association Between Major Depressive Disorder and Alopecia Areata: A Population-Based Study
Depression and hair loss may influence each other.
research Neuroactive Steroid Levels and Psychiatric and Andrological Features in Post-Finasteride Patients
Post-finasteride patients show changed neuroactive steroid levels, possibly causing erectile dysfunction and depression.
research Physical Properties of Human Hair: Evaluation of Bending Stress by Measuring the Major and Minor Axis of Human Hair
The cuticle significantly contributes to hair stiffness, making up about 60% of the total bending stress.
research Hair Loss as a Side Effect of Quetiapine: A Clinical Case Report
Quetiapine may cause hair loss.
research Major Approaches of Molecular and Physiopathological Mechanisms for Hormonal Treatment of Melasma: A Systematic Review
Estrogens and progesterone are key in regulating melasma pigmentation.
research Assessment of a Bidirectional Association Between Major Depressive Disorder and Alopecia Areata
People with Major Depressive Disorder have a higher chance of getting Alopecia Areata, and vice versa; antidepressants may lower this risk.
research Major Depletion of SOX2+ Stem Cells in the Adult Pituitary Is Not Restored and Does Not Affect Hormonal Cell Homeostasis and Remodeling
The pituitary gland functions normally even after losing most SOX2+ stem cells.
research Is Tadalafil Associated With Decreased Risk of Major Adverse Cardiac Events or Venous Thromboembolism in Men With Lower Urinary Tract Symptoms?
Tadalafil may reduce the risk of major heart events and blood clots in men with urinary symptoms.
research Major Randomized Clinical Studies of Alopecia Treatment With Platelet-Rich Plasma: A Systematic Review
PRP effectively treats hair loss, especially when combined with microneedling or minoxidil.
research Hidradenitis Suppurativa and Major Adverse Cardiac Events: A Systematic Review and Meta-Analysis
People with hidradenitis suppurativa have a higher risk of heart attacks and strokes.
research Persistent Major Alopecia Following Adjuvant Docetaxel for Breast Cancer: Incidence, Characteristics, and Prevention with Scalp Cooling
Scalp cooling effectively prevents severe hair loss in breast cancer patients treated with docetaxel and is safe.
research Ketoconazole in Cutaneous Leishmaniasis
Ketoconazole cured about 70% of cutaneous leishmaniasis cases caused by Leishmania major.
research The Long And The Short Of It: Evidence That FGF5 Is A Major Determinant Of Canine Hair-Itability
The FGF5 gene determines hair length in dogs.
research Meetings, Transactions, and Society News
Two major dermatology conferences were held in 2006, focusing on skin immunity and various skin diseases.
research Obesity in Adults: Position Statement of Various Polish Medical Associations
The conclusion is that obesity should be managed with a slow, balanced approach to diet and exercise, with medication and surgery as additional options, and education and access to care are important.
research Contemporaneous Onset of Systemic Lupus Erythematosus and Severe Eating Disorder: Neither the Chicken Nor the Egg
Hormonal changes and social stress may link lupus and eating disorders in teens.