13 citations
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May 2016 in “International journal of biological macromolecules” This study demonstrated that molecular dynamics simulations of keratin could effectively model the mechanical properties of hair, aligning well with experimental data, especially when conducted in vacuum conditions.
12 citations
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August 2021 in “International Journal of Biological Macromolecules” This study observed that Poria cocos polysaccharides and finasteride both reduced inflammation in chronic nonbacterial prostatitis in rats, but only Poria cocos polysaccharides reversed related changes in the gut microbiota.
11 citations
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January 2016 in “International Journal of Biological Macromolecules” This study found that enzymatic phosphorylation of hair keratin increased its capacity to adsorb cationic components like methylene blue and may have practical implications for hair care products.
10 citations
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January 2012 in “Journal of Biological Macromolecules” This study found that keratin film from human hair samples responded to damage from UV, bleaching, perming, and thermal treatments, making it a useful model for evaluating hair damage in product development.
8 citations
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May 2020 in “International journal of biological macromolecules” In this study, researchers evaluated the binding of keratin-associated proteins and α-keratins to human hair fibers, finding that chemical preactivation significantly enhanced binding to natural hair, while perming altered binding characteristics and increased penetration depth.
6 citations
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December 2024 in “International Journal of Biological Macromolecules” This study introduced a novel exosome-loaded sprayable hydrogel (ADA-aPF127@LL18/Exo) that significantly enhanced wound healing in a deep partial thickness burn model, showing improved antibacterial efficacy and promoting tissue recovery processes like epithelialization and hair follicle regeneration.
5 citations
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July 2023 in “International journal of biological macromolecules” This research observed that a silver nanoparticle-loaded polydopamine/polyethyleneimine-coated bacterial cellulose dressing effectively inhibited S. aureus infections, reduced inflammation, and promoted wound healing compared with untreated cellulose, demonstrating its potential for treating infected wounds.
5 citations
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December 2020 in “International journal of biological macromolecules” This study found that shikimic acid- and maleate-based hair repair agents modified the structure of hair fibers, though they did not increase disulfide bridge content in the hair cortex.
4 citations
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November 2024 in “International Journal of Biological Macromolecules” In this study, the researchers developed a cellulose nanofiber-based scaffold containing sitagliptin and zinc sulfide nanoparticles, which promoted scarless healing and hair follicle regeneration in rats by targeting DPP4+ fibroblasts, suggesting a novel approach for improved wound healing and skin regeneration.
4 citations
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September 2023 in “International journal of biological macromolecules” This study found that a silver ion cross-linked thiolated protein hydrogel, O3G7, significantly enhanced acute wound healing in mice by increasing collagen content, neovascularization, and reducing inflammation markers compared to a control group.
4 citations
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April 2022 in “International Journal of Biological Macromolecules” In this study, researchers reported that wound dressings made from bacterial cellulose composites modified with soybean protein (BC/7S and BC/11S) improved wound healing and reduced scarring in rat models, with BC/11S showing superior outcomes.
3 citations
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January 2025 in “International Journal of Biological Macromolecules” This study found that a microneedle patch containing tofacitinib-loaded nanoparticles significantly increased hair follicle numbers and promoted hair regeneration with less drug compared to daily topical tofacitinib, suggesting it may be an effective strategy for alopecia treatment by reducing dosing frequency and enhancing drug delivery.
3 citations
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July 2023 in “International Journal of Biological Macromolecules” In this study, the researchers developed a hydrogel mimicking the fetal environment that significantly accelerated wound healing and hair follicle regeneration in vivo, with over 94% wound closure in 14 days, surpassing hydrogels lacking certain additives.
3 citations
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May 2012 in “Journal of Biological Macromolecules” Keratin film can effectively mimic human hair for testing hair damage.
1 citations
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April 2025 in “International Journal of Biological Macromolecules” This study found that Forskolin-loaded carboxymethyl chitosan-silk nanofiber hydrogels promoted wound healing by accelerating wound closure, enhancing neovascularization, and supporting hair follicle regeneration, while also being non-toxic and encouraging the proliferation of certain cell types.
1 citations
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September 2023 in “International Journal of Biological Macromolecules” This study found that a novel in-situ crosslinked self-healing hydrogel made from oxidized Bletilla striata polysaccharide and cationic gelatin enhanced wound healing and showed strong hemostatic performance in animal models, suggesting its potential as an effective wound dressing for skin trauma.
1 citations
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July 2023 in “International Journal of Biological Macromolecules” In this study, researchers developed a composite paste system using minoxidil-loaded nanoparticles and valproic acid, enhanced by roller-microneedles, which significantly stimulated hair regeneration and perifollicular vascularization in an androgenetic alopecia mouse model, reducing side effects compared to traditional treatments.
1 citations
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June 2023 in “International journal of biological macromolecules” In this preclinical study, researchers found that combining equal ratios of high molecular weight keratin intermediate filaments and low molecular weight keratin-associated proteins from human hair led to the most extensive fibrinogen precipitation, suggesting potential for developing effective hair protein-based hemostatic materials.
May 2026 in “International Journal of Biological Macromolecules”
May 2026 in “International Journal of Biological Macromolecules” In this study, researchers developed a biomacromolecular hydrogel to deliver plant-derived extracellular vesicles for treating androgenetic alopecia in a mouse model, which significantly improved hair regrowth and follicle density by activating Wnt/β-catenin signaling.
April 2026 in “International Journal of Biological Macromolecules” March 2026 in “International Journal of Biological Macromolecules” Recombinant Filaggrin-2 microneedles effectively promote hair growth and repair in hair loss.
February 2026 in “International Journal of Biological Macromolecules” In this study, researchers developed a novel periodate oxidation method for extracting keratin micro-units from waste hair and feathers, achieving yields of 31.28% and 20.64% respectively, enhancing the stability of oil-in-water emulsions and suggesting potential for sustainable biomaterial production.
January 2026 in “International Journal of Biological Macromolecules” January 2026 in “International Journal of Biological Macromolecules” The hydrogel improves hair growth treatment by enhancing drug delivery and promoting follicle repair.
January 2026 in “International Journal of Biological Macromolecules” This study used a new multimolecular spectral method to uncover structural differences in hair keratin from individuals with androgenetic alopecia compared to healthy individuals, identifying potential biomarkers and providing insights for developing new treatments.
January 2026 in “International Journal of Biological Macromolecules” This study found that different polypeptides, including KP peptide and hydrolyzed keratin, can improve the mechanical properties of damaged hair under varying conditions, with reduction environments and cysteine content influencing their effectiveness.
November 2025 in “International Journal of Biological Macromolecules” This study introduced an eco-friendly enzymatic hair dyeing process utilizing laccase-catalyzed polymerization of hematoxylin, achieving intense, long-lasting color comparable to commercial dyes while enhancing hair strength and offering antioxidant and UV-shielding benefits.
September 2025 in “International Journal of Biological Macromolecules” In an animal study with a skin defect model, this research reported that curcumin-loaded hydrogels made from recombinant humanized collagen and an eco-friendly crosslinker enhanced wound repair by promoting angiogenesis, granulation tissue formation, and hair follicle neogenesis, while providing antioxidant benefits.
August 2025 in “International Journal of Biological Macromolecules” A new hydrogel can kill resistant bacteria and help heal infected burn wounds.