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This study reports on a unique clinical presentation of folliculotropic mycosis fungoides in a 60-year-old man, highlighting complexities in diagnosis due to dense histiocytic infiltration, which led to xanthoma formation before treatment, and obscured lymphomatous features.

This study found that a microneedle system delivering VEGF and Ritlecitinib improved hair regeneration in mice with androgenetic alopecia, showing faster anagen onset and better hair quality compared to minoxidil.

This study found that a nanoemulsion containing perfluorooctyl bromide effectively increased oxygen levels in an anoxic environment, enhancing hair dermal papilla cell growth and significantly promoting hair organ elongation.

This study observed that incorporating human follicle dermal papilla cells into fibrin microgels increased cell viability and the formation of hair follicle structures in in vitro skin cultures compared to traditional dermal papilla spheroids, suggesting a promising approach for hair follicle regeneration therapies.

This review concludes that chronic inflammation can lead to persistent activation of stem cells, accumulating DNA damage that promotes cancer development and metastasis, by affecting normal stem cells, cancer stem cells, and cancer cells.

This review highlights that chronic inflammation leads to ongoing activation of stem cells, causing DNA damage accumulation, which can promote cancer development and metastasis.

In this review, researchers concluded that chronic inflammation perpetually activates stem cells, allowing DNA damage accumulation and potentially promoting cancer development and metastasis by converting stem cells into cancer cells.

This literature review reports that chronic inflammation can lead to persistent activation of stem cells, accumulating DNA damage, and eventually promoting cancer development and metastasis even before stem cells become cancerous.

This review concludes that chronic inflammation can lead to persistent activation of stem cells, which may accumulate DNA damage and ultimately promote cancer, while also facilitating cancer metastasis.

This study found that in a mouse model of Gorlin syndrome, constitutive activation of signaling in dermal cells led to abnormal follicular growth, indicating non-epidermal factors may contribute to the disease.

This study found that different stressors causing premature senescence in fibroblasts resulted in distinct changes in lipid profiles, particularly sphingolipids, which may affect the behavior of senescent skin cells.

This study found that physoxia improved hair follicle functions in co-cultures of dermal papilla cells and melanocytes by enhancing their biological activities and promoting hair growth and pigmentation.

This study found that using 3D cultures and fetal tissue extracts significantly improved the outcomes of stem cell treatments for regenerative medicine, including hair follicle formation and chronic wound healing.

This study found that the loss of transcription factor Ovol2 in epidermal and hair follicle stem cells leads to migration defects, which are partially improved by deleting the EMT-inducing Zeb1.

In this study, melatonin exposure promoted hair follicle fiber growth in Cashmere goats, suggesting that it may mediate hair follicle development through long non-coding RNAs affecting vascular and extracellular pathways.

This study explored the potential of hair follicle dermal papilla cells for multilineage differentiation in embryos, highlighting their plasticity and regenerative capabilities.

In this study, researchers observed that dormant TRP-2+ melanoma cells in bone marrow can interact with CD8+ T cells in tumor-bearing ret transgenic mice, potentially influencing immune responses.

This study found that CMV infection in a mouse model of allogeneic transplantation was associated with increased allo-reactive T cell expansion and exacerbated graft-versus-host disease, highlighting the need for effective GvHD prophylaxis and treatment.

This review explores hypotheses about hair follicle stem cell function in morphogenesis and cycling, highlights the importance of dermal papilla cells and signaling pathways, and provides no new clinical findings.

This review discusses various tissue engineering approaches for hair follicle regeneration and biomaterials used, emphasizing its potential despite current clinical challenges.

This essay discusses the establishment, maintenance, and role of skin stem cells in tissue homeostasis, wound repair, and their relation to skin cancer, without reporting new experimental findings.

This research discusses the potential antitumor effects of metformin, a common diabetes medication, noting its controversial influence on different malignant tumors and its uncertain mechanisms. Understanding these effects on tumors may aid in the development of new cancer treatments.

New pharmaceutical biomaterials, especially nanomaterials, show promise for improving cancer treatment and disease diagnosis.

This study suggests that human skin contains distinct fibroblast subsets with unique expression profiles and functions, which can be isolated to investigate their role in skin pathogenesis.

This review outlines the various fibroblast subsets in the skin dermis, their origins, and their influence on epidermal stem cell behavior, highlighting the role of the local dermal niche in stem cell plasticity.

This study found that mitochondrial fusion regulator Opa1 is crucial for maintaining melanocyte stem cells during the hair follicle cycle in mice, with Opa1 deficiency leading to impaired SCF-KIT signaling, reduced melanocyte populations, and early hair graying.

This study observed that pantethine, a vitamin B5 precursor, attenuates tumor growth in immunocompetent mice by enhancing antitumor immunity, but its effect is limited by immune cell exhaustion over time.

This article reviews the generation of complex integument patterns through genetic, chemical, and environmental influences, with applications in tissue engineering, but reports no new experimental results.

This review discusses experimental data, technologies, and genetic factors related to stem cell niches, highlighting their role in tissue regeneration and diseases, but reports no new results.

This study found that super-enhancers are essential for hair follicle stem cell identity, lineage commitment, and plasticity in mice, with SOX9 being a key regulator of these chromatin dynamics.