research Topical Application of Thymidine Dinucleotide to Newborn Mice Reduces and Delays Development of UV-Induced Melanomas
Putting thymidine dinucleotide on newborn mice's skin can delay and reduce skin cancer.
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research Androgen Metabolism as It Affects Hair Growth in Androgenetic Alopecia
Androgens, like DHT, affect hair growth and treatments like finasteride may help.
research Connexin 43 Expression in the Testes During Postnatal Development of Finasteride-Treated Male Rat Offspring
Finasteride treatment changes Cx43 in rat testes, possibly causing fertility issues.
research mTORC1 Activity Controls Human Scalp Hair Follicle Pigmentation and Growth
mTORC1 activity is important for hair growth and color, and targeting it could help treat hair loss and greying.
research Hair Growth Properties of Cinchona Succirubra Extract, Leontopodium Alpinum Extract, and Manganese PCA in Human Hair Follicle Dermal Papilla Cells
The ingredients could help prevent hair loss by promoting hair growth and increasing VEGF secretion.
research Female Pattern Hair Loss, Biological Aging, and the Leiden Longevity Study
Women with aging signs and heart issues have higher hair loss risk, which may predict shorter lifespan and affect attractiveness.
research Polycystic Ovarian Syndrome Elevates the Distress of Sexual Pain in Iranian Women with Infertility
PCOS increases sexual pain distress in infertile women.
research Analytical Methods of Dutasteride: An Overview
Dutasteride is more effective than finasteride for hair loss treatment.
research Alk1 Acts in Non-Endothelial VE-Cadherin+ Perineurial Cells to Maintain Nerve Branching During Hair Homeostasis
Alk1 in specific cells is crucial for proper nerve branching and hair function.
research Prostate Specific Antigen as a Predictive Factor for Androgenemia in Women
PSA can help diagnose high androgen levels in women.
research Evaluation of Anti-Hair Loss Shampoo Through In Vitro Activity in Human Hair Follicle Dermal Papilla Cells and Sensorial Study
The anti-hair loss shampoo effectively promotes hair growth and improves hair quality.
research Mapping the Establishment of Fibroblast Heterogeneity During Skin Development and Wound Repair
Skin heals with scars because only one type of fibroblast is used, not a mix.
research Penis Endocrinology
Hormones, especially testosterone and DHT, are key for penis development and function, and testosterone therapy may help with erectile dysfunction in those with low levels.
research Editors' Picks
Collagen VII helps skin heal and stay strong, sirolimus may lower skin cancer risk in kidney transplant patients, high-molecular-mass hyaluronan helps naked mole rats resist cancer, dermal γδ T cells aid in hair growth in rodents, and overexpression of IL-33 in mouse skin causes itchiness, offering a model for studying allergic inflammation treatments.
research Analysis of Thymosin β4 and Vascular Endothelial Growth Factor Expression in Normal Human Tissues Using Tissue Microarray
Thymosin β4 and VEGF are important for blood vessel formation in many organs.
research Time Lags Between Various Maturity Measures and Spermarche
Certain maturity signs appear before and after the first release of sperm in boys.
research Protective Effect of DA-9401 in Finasteride-Induced Apoptosis in Rat Testis: Inositol Requiring Kinase 1 and c-Jun N-Terminal Kinase Pathway
Finasteride helps female-pattern hair loss.
research Stem Cells and the Niche: A Dynamic Duo
Stem cell niches are crucial for regulating stem cell behavior and tissue health, and their decline can impact aging and cancer.
research Targeting Oxidative Stress and Mitochondrial Dysfunction in the Treatment of Impaired Wound Healing: A Systematic Review
Treatments that reduce oxidative stress and fix mitochondrial problems may help heal chronic wounds.
research Interrelation of Immunity and Tissue Repair or Regeneration
The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.
research 5α-Reductase Activity in the Prostate
Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.
research ATP-Dependent Chromatin Remodeling During Mammalian Development
ATP-dependent chromatin-remodeling complexes are crucial for gene regulation, cell differentiation, and organ development in mammals.
research Cartilage to Bone Transformation During Fracture Healing Is Coordinated by the Invading Vasculature and Induction of the Core Pluripotency Genes
Blood vessels and specific genes help turn cartilage into bone when bones heal.
research Prevention of Chemotherapy-Induced Alopecia in Rats by CDK Inhibitors
Using CDK inhibitors on rats showed a reduction in chemotherapy-caused hair loss, but later experiments could not repeat these results.
research Adult Polycystic Ovary Syndrome Begins in Childhood
Polycystic Ovary Syndrome likely starts in childhood and may be genetic and influenced by early hormone exposure.
research MIM and Cortactin Antagonism Regulates Ciliogenesis and Hedgehog Signaling
MIM is crucial for hair follicle formation and regeneration by controlling cilia formation and hedgehog signaling through its interaction with Cortactin and Src.
research Zinc: An Essential Trace Element for Parenteral Nutrition
Zinc is crucial for nutrition, especially in patients with specific health conditions, and requires careful supplementation and monitoring.
research Regulatory T Cells in Skin: Role of Foxp3+ CD4+ Tregs in Skin Homeostasis and Immune Tolerance
Skin's Regulatory T cells are crucial for maintaining skin health and could be targeted to treat immune-related skin diseases and cancer.
research Pharmacology of Antiandrogens
Antiandrogens affect androgen-dependent body functions and are used for various medical conditions, with some risks like fetus feminization, but new forms like 17α-propylmesterolone show promise for acne without systemic effects.
research Stratum Corneum Dysfunction in Dandruff
Improving skin barrier and using antifungal treatments can help manage dandruff.