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May 2021 in “Scientific Reports” In this study, researchers found that stress likely triggers symmetrical alopecia in Formosan macaques in Mt. Longevity, Taiwan, with higher stress hormone levels associated with the condition.
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January 2018 in “PubMed” This case report describes a 45-year-old man with a pituitary macroadenoma whose symptoms and tumor size improved significantly after one month of treatment with cabergoline.
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December 2024 in “Case Reports in Dermatology” In this case study, the researchers reported a rare incidence of bilateral hyperpigmented macules on a patient's lower legs, possibly due to cyclophosphamide, suggesting that this chemotherapy drug may directly stimulate hair follicles to cause skin discoloration.
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June 2022 in “Chinese medical journal/Chinese Medical Journal” This study identified two novel mutations in the CDH3 gene causing HJMD in a Chinese patient, expanding the genetic and phenotypic understanding of the disorder.
July 2024 in “Journal of Investigative Dermatology” Certain substances can help skin cells become anti-inflammatory, aiding in tissue repair.
July 2023 in “The Journal of Family Practice” This case study describes a 29-year-old man who presented with a fever and a generalized maculopapular rash, alongside symptoms like hair loss and joint pain, leading to an investigation into whether his condition was a case of the "great masquerader.
August 2026 in “International Journal of Molecular Sciences” This study found that Atractylodes macrocephala Koidz. extract promotes anagen entry and hair regrowth by enhancing dermal papilla cell activity and supporting hair cycle progression in a mouse model.
July 2026 in “Industrial and Domestic Waste Management” This study synthesized silver nanoparticles using Gandaria stem bark extract, finding that nanoparticles at a 4% concentration were particularly effective for selectively detecting mercury over lead and calcium, making them suitable as preliminary detection materials for mercury in facial whitening creams.
This study found that social hair plucking in captive rhesus macaques may share traits with both prosocial and aggressive behaviors and is associated with alopecia and hair cortisol levels.
May 2026 in “Materials & Design” This study developed a hair-on-a-chip model that supports the maturation of hair-follicle-like tissue under long-term culture conditions, suggesting its promise for studying hair regeneration and testing scalp-targeted therapies.
In a case report, this study identified a new genetic variant in a six-year-old girl from Saudi Arabia with hypotrichosis and juvenile macular dystrophy, expanding the understanding of the genetic spectrum of this rare condition in the region.
January 2026 in “International Society of Hair Restoration Surgery” This study reports that a novel multimodal approach, combining tattoo machine–assisted drug delivery of hair loss treatments with oral and topical medications, may enhance hair density and thickness in androgenetic alopecia patients, though larger controlled studies are needed to confirm these early findings.
December 2025 in “Journal of Pharma Insights and Research.” This paper reviews the state of knowledge on injectable cryogels, highlighting their unique properties such as shape-memory and mechanical integrity, which allow for minimally invasive delivery via needles and potential applications in oncology and regenerative medicine.
July 2025 in “Journal of Investigative Dermatology” Schwann cell and M2 macrophage interactions contribute to keloid growth by increasing matrix deposition.
July 2025 in “Journal of Investigative Dermatology” This study found that both desmoglein-specific and non-desmoglein autoantibodies may play active roles in Pemphigus vulgaris pathogenesis, with HLA genetics influencing autoimmune specificity.
April 2025 in “Science Journal of University of Zakho” This study found that higher Dietary Inflammatory Index scores were significantly associated with an increase in both the occurrence and severity of alopecia areata.
January 2025 in “Dermatology Research and Practice” In this research, RNA expression analysis of scalp biopsies from lichen planopilaris patients revealed changes in specific genes after treatments with hydroxychloroquine, narrow band UVB, or low level laser light therapy, suggesting potential biomarkers and implicating M2 macrophages in the disease's immunopathogenesis.
December 2024 in “Jurnal Mandala Pharmacon Indonesia” In this study, high-dose oral administration of Ramania leaf ethanol extract in Wistar rats resulted in no significant acute toxicity symptoms, though gastric ulcers and hair loss were observed. The extract is classified as non-toxic under specified guidelines, with an LD50 greater than 5000 mg/kg.
October 2024 in “Journal of Cutaneous Immunology and Allergy” This case report describes a successful treatment of sarcoidal foreign body reactions caused by permanent makeup ink with local steroid injections, while also identifying the involvement of M2 macrophages in the reaction.
July 2024 in “Heart Lung and Circulation” Age, diabetes, and cardiogenic shock at PCI are key factors linked to in-hospital death in STEMI patients with hypertension.
June 2024 in “Current Developments in Nutrition” This study found that a nutritional intervention in dogs can alleviate atopic dermatitis symptoms by modulating immune responses and altering skin microbiome composition, which includes reducing fungal diversity and the abundance of pathogenic species such as Malassezia pachydermatis.
This study aims to develop an automatic machine learning-based method using the VGG-19 model to accurately classify various hair and scalp diseases.
This review explores the extraction, characterization, and skin cosmetic effects of phenolic compounds and pigments from marine macroalgae, highlighting their documented benefits for skin health, such as whitening, moisturizing, photoprotection, and anti-aging effects, without adverse health impacts.
May 2023 in “Journal of Ethnopharmacology” In this study, Allium macrostemon Bunge extract was found to promote hair regrowth in a testosterone-induced androgenetic alopecia mouse model by activating Wnt/β-catenin signaling and boosting hair dermal papilla cell proliferation and growth factor expression.
April 2023 in “Journal of Investigative Dermatology” This study identified a new role for IL-4Ra-induced oxidative metabolism in wound macrophages, essential for balancing inflammatory response and promoting pro-fibrotic repair, suggesting a target for fibrosis prevention.
April 2023 in “Journal of Investigative Dermatology” CD206+ macrophages are crucial for hair growth in alopecia areata treatment.
December 2022 in “Research Square (Research Square)” In this study, the researchers developed a quantum algorithm, QuantAnts machines, which identified complexes of CD9, CD34, and CD74 as potential targets for certain cancers involving the RAS pathway.
July 2022 in “Journal of Investigative Dermatology” Arg1+ macrophages may play a role in Alopecia Areata, offering new treatment targets.
April 2021 in “Journal of Investigative Dermatology” Arg1+ macrophages may play a role in causing alopecia areata.
April 2021 in “Sri Lanka Journal of Diabetes Endocrinology and Metabolism” This study reports a case of Cushing disease caused by a rare giant pituitary macroadenoma in a 41-year-old woman, requiring additional treatment after unsuccessful surgery.