14 citations
,
March 2018 in “Translational Stroke Research” In this animal study, researchers found that finasteride may offer neuroprotective benefits as a post-ischemic treatment for strokes in aged male rats, suggesting its potential as a therapeutic agent in this context.
14 citations
,
March 2010 in “Gynecological endocrinology” This article provides an overview of treatment options for hirsutism, summarizing both pharmacologic and non-pharmacologic approaches, but reports no new clinical results.
14 citations
,
December 1998 in “The Journal of Clinical Endocrinology and Metabolism” This study found that MENT is 10 times more potent than testosterone in suppressing gonadotropins and contributing to anabolism in monkeys, with a potentially wider therapeutic index for human androgen replacement and male contraception.
14 citations
,
May 2022 in “Cell Reports” In this study, researchers found that basal cell carcinomas with common Hedgehog signaling mutations may require additional mutations to hyperactivate downstream signaling and progress beyond dormancy.
14 citations
,
August 2021 in “Molecular Genetics and Metabolism Reports” This case series highlights the real-world challenges and experiences of US healthcare providers using pegvaliase for phenylketonuria treatment, emphasizing patient education on adverse events and dietary changes, and tailored titration schedules, while reporting that most patients achieved treatment efficacy despite initial adverse events.
14 citations
,
May 2021 in “Marine Drugs” This review discusses the therapeutic properties of polydeoxyribonucleotides derived from marine organisms for wound healing and inflammation, but it reports no new clinical results.
14 citations
,
October 2019 in “Journal of Cellular Physiology” This study found that dermis micrografting improved hair growth and density in patients with androgenetic alopecia over 4, 6, and 12 months, suggesting it could be a novel treatment option.
14 citations
,
October 2016 in “Physiological Research” In this study, vitamin D supplementation showed no significant effect on androgen levels or clinical hyperandrogenism in PCOS women, but when combined with metformin, it improved testosterone levels.
14 citations
,
June 2016 in “Biomaterials” This study observed that MAA beads improved vascularization in non-diabetic male mice by modulating the Shh signaling pathway in wound granulation tissue, but showed no such effects in females.
14 citations
,
June 2016 in “Pediatric Dermatology” This review discusses the prognosis and treatment options for hair shaft disorders, finding no studies but suggesting some disorders improve with specific treatments like minoxidil and retinoids, while gentle hair care remains essential.
14 citations
,
January 2016 in “Experimental Dermatology” This analysis concluded that hair regrowth in male and female pattern hair loss treatments did not involve converting vellus hairs into terminal hairs, suggesting a reactivation of dormant non-vellus follicles instead.
14 citations
,
July 2015 in “Journal of Cosmetic Dermatology” This study found that, in Japanese patients with androgenic alopecia, sebaceous glands exhibit increased multilobulation which may be significant in the condition's pathology.
14 citations
,
May 2014 in “Archives of plastic surgery” This study found that among Korean males with male pattern baldness, hair loss mostly progresses within 6 cm from the parietal whorl towards the occipital side.
14 citations
,
April 2011 in “Journal of the American Academy of Dermatology” Researchers found a gene mutation responsible for a rare hair loss condition.
14 citations
,
February 2011 in “Experimental dermatology” This study identifies cartilage oligomeric matrix protein (COMP) as a key extracellular matrix component in human hair follicle cycling, potentially regulated by TGFβ signaling, and suggests its importance in normal hair follicle biology.
14 citations
,
December 2010 in “Dermatologica Sinica” This article reviews recent advances and therapeutic approaches in treating alopecia areata, highlighting new potential treatments like pulse corticosteroid therapy, but reports no new research findings.
14 citations
,
July 2010 in “Experimental Dermatology” A new mutation in the HR gene causes hair loss in a specific family.
14 citations
,
December 2007 in “Pediatric allergy and immunology” In this study, researchers found that mast cells in Erythema Toxicum lesions in newborns are actively involved in the immune response around hair follicles, but do not express the antimicrobial peptide LL-37.
14 citations
,
September 2003 in “Archives of Dermatology” This abstract provides no new data or findings as it is a placeholder text rather than a research summary.
14 citations
,
October 2002 in “Journal of cutaneous pathology” This study found that MAP-2 is intensely expressed in the companion layer of the hair follicle, suggesting its potential importance to follicle integrity and possible involvement in some types of alopecia.
14 citations
,
March 2002 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that serum MIF levels were significantly higher in patients with extensive alopecia areata compared to those with mild alopecia areata and healthy individuals.
14 citations
,
July 1994 in “Journal of Investigative Dermatology” 14 citations
,
September 1990 in “Journal of the American Academy of Dermatology” In this study, viprostol was not effective in promoting hair growth for men with androgenetic alopecia over a 24-week period.
14 citations
,
January 1990 in “Fertility and Sterility” In this study, five patients with moderate hyperprolactinemia lacked symptoms, signs, or underlying causes, leading researchers to conclude that no further investigation or therapy was needed.
13 citations
,
September 2022 in “Journal of Drugs in Dermatology” This study suggests that antihistamines show promise as adjunct treatments for alopecia areata, but the role of dupilumab needs further investigation due to mixed results regarding hair regrowth and adverse effects.
13 citations
,
February 2022 in “JAMA Dermatology” This meta-analysis reported that 0.5 mg/d of dutasteride significantly increased total hair count at 24 weeks compared to finasteride and minoxidil in men with androgenetic alopecia.
13 citations
,
July 2019 in “Pediatric dermatology” This review addresses dermatologic health disparities in sexual and gender minority adolescents, highlighting the need for improved pediatric dermatologic care; it does not report new clinical results.
13 citations
,
June 2018 in “Current Urology Reports” This review suggests that while finasteride for male pattern hair loss was previously considered safe, there is now evidence associating 5-α reductase inhibitors with significant sexual and reproductive side effects.
13 citations
,
August 2016 in “Medical Hypotheses” This review discusses the potential of evaluating hair follicle characteristics as early indicators of vascular impairment and organ damage in pre-diabetic individuals, but reports no new clinical results.
13 citations
,
July 2012 in “Pigment Cell & Melanoma Research” In this study, researchers identified a new dominant mutation in Hairless mice, called Pied, resulting from a deletion in the Adam10 gene, which causes freckle-like skin pigmentation by inhibiting melanocyte expansion.