research FGF Family: From Drug Development to Clinical Application
FGF signaling is a promising target for developing treatments for wounds, metabolic diseases, and cancer.
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research Neurosteroids, Neuroactive Steroids, and Symptoms of Affective Disorders
Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.
research Functional Enhancement Strategies for Immunomodulation of Mesenchymal Stem Cells and Their Therapeutic Application
New methods to improve the healing abilities of mesenchymal stem cells for disease treatment are promising but need more research.
research Applications and Implications of Heparin and Protamine in Tissue Engineering and Regenerative Medicine
Heparin and protamine are promising in tissue repair and organ regeneration, including skin and hair.
research A Review of Coumarin Derivatives in Pharmacotherapy of Breast Cancer
Coumarin derivatives show promise as anti-estrogenic agents for treating breast cancer, with some in clinical trials.
research Follicle Hormones
Follicle Stimulating Hormone is important for fertility.
research TGFβ and Cancer Metastasis: An Inflammation Link
TGFβ's manipulation of inflammation and immune cells affects cancer spread, suggesting new treatment strategies and biomarkers.
research New Steps Forward in the Neuroactive Steroid Field
Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.
research Preservation of Melanoblasts in White Hair Follicles of Segmental Vitiligo Lesions: A Preliminary Study
White hair follicles in vitiligo have fewer and less functional melanocytes.
research Activin A-Induced Signaling Controls Hair Follicle Neogenesis
Activin A is important for creating new hair follicles.
research Clinical and Neuropathogenetic Aspects of Human African Trypanosomiasis
The document concludes that diagnosing and treating Human African Trypanosomiasis is challenging, but new treatments like fexinidazole are promising.
research Promoting Axonal Regeneration Through Exosomes: An Update of Recent Findings on Exosomal PTEN and mTOR Modifiers
Exosomes help nerve fibers grow by affecting specific cell signaling pathways.
research Immune-Mediated Diseases of the Central Nervous System
The document explains the difficulty in diagnosing and treating brain diseases caused by the immune system and stresses the need for quick and accurate tests.
research Clinical Guidance on the Monitoring and Management of Trastuzumab Deruxtecan (T-DXd)-Related Adverse Events: Insights from an Asia-Pacific Multidisciplinary Panel
Proactive monitoring and management are essential to maximize the benefits of Trastuzumab Deruxtecan while minimizing serious side effects.
research Managing the Adverse Effects of Cytotoxic Chemotherapy at the Level of Primary Healthcare
Primary healthcare clinics are key in managing chemotherapy side effects using various medications and treatments.
research Hair-Growth-Promoting Effect of Conditioned Medium of High Integrin α6 and Low CD71 Positive Keratinocyte Cells
A special mix from certain skin cells can help hair grow by making hair root cells grow faster and activating growth signals.
research CXCL12 Inhibits Hair Growth Through CXCR4
CXCL12 protein slows down hair growth through its receptor CXCR4. Blocking this can potentially increase hair growth.
research 17β-Estradiol Inhibits the Production of RANTES in Human Keratinocytes
17β-estradiol can reduce inflammation in the skin.
research Ayurveda-Based Botanicals as Therapeutic Adjuvants in Paclitaxel-Induced Myelosuppression
Asparagus racemosus and Withania somnifera can help reduce side effects of a cancer drug.
research Efficacy and Safety of Proxalutamide in Severe or Critically Ill COVID-19 Patients: Study Protocol for an Exploratory Trial
The trial will test if proxalutamide is safe and effective in reducing death in severe COVID-19 patients.
research Insights Into the Scenario of SARS-CoV-2 Infection in Male Reproductive Toxicity
COVID-19 may harm male reproductive health and lower testosterone levels, potentially affecting fertility and causing erectile dysfunction. More research is needed.
research Regulation of Stem Cell Fate by HSPGs: Implication in Hair Follicle Cycling
HSPGs help control stem cell behavior, affecting hair growth and offering a target for hair loss treatments.
research Stress-Induced Production of Chemokines by Hair Follicles Regulates the Trafficking of Dendritic Cells in Skin
Hair follicles help attract immune cells to the skin during stress.
research Epidermal Keratinocyte Stem Cells: Their Maintenance and Regulation
Skin stem cells are maintained by signals from nearby cells and vary in their ability to renew and mature.
research T Cell and Bacterial Microbiota Interaction at Intestinal and Skin Epithelial Interfaces
T cells and bacteria in the gut and skin help maintain health and protect against disease.
research Neuroactive Steroid Levels and Psychiatric and Andrological Features in Post-Finasteride Patients
Post-finasteride patients show changed neuroactive steroid levels, possibly causing erectile dysfunction and depression.
research Altered Methylation Pattern of the SRD5A2 Gene in the Cerebrospinal Fluid of Post-Finasteride Patients: A Pilot Study
Finasteride affects SRD5A2 gene pattern, possibly causing lasting side effects.
research The Role of Topical Vitamin D in Vitiligo: A Narrative Literature Review
Topical vitamin D is effective in treating vitiligo with few side effects.
research Skin Melanocytes: Biology and Development
The paper concludes that understanding melanocyte development can help in insights into skin diseases and melanoma diversity.
research Persistent Sexual, Emotional, and Cognitive Impairment Post-Finasteride
Finasteride can cause lasting sexual, emotional, and cognitive issues, with varying severity.