research Finasteride-Induced Inhibition of 5α-Reductase Type 2 Could Lead to Kidney Damage: An Experimental Animal Study
Finasteride may cause kidney damage.
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research Short-Term Cryoprotectant-Free Cryopreservation at −20°C Does Not Affect the Viability and Regenerative Capacity of Nanofat
Storing nanofat at -20°C for 7 days does not harm its ability to regenerate.
research Physiological Doses of Red Light Induce IL-4 Release in Cocultures Between Human Keratinocytes and Immune Cells
Red light at 627 nm can safely trigger IL-4 release in skin cells, potentially helping treat inflammatory skin conditions.
research Wound Healing: A Cellular Perspective
The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.
research Mesenchymal Stromal Cell Secretome: Influencing Therapeutic Potential by Cellular Pre-Conditioning
Changing how mesenchymal stromal cells are grown can improve their healing abilities.
research Repurposing of Approved Cardiovascular Drugs
Some heart drugs show promise for other conditions, but more research is needed to confirm their effectiveness and safety.
research The Antiandrogen Enzalutamide Downregulates TMPRSS2 and Reduces Cellular Entry of SARS-CoV-2 in Human Lung Cells
The drug enzalutamide may reduce the ability of the virus causing COVID-19 to enter lung cells.
research Oral Syphilis: Report of Three Cases and Characterization of the Inflammatory Cells
The document concludes that recognizing oral lesions is important for diagnosing syphilis.
research The Topography of Fibrous Scaffolds Modulates the Paracrine Function of Adipose-Derived Mesenchymal Stem Cells in the Regeneration of Skin Tissues
The shape of fibrous scaffolds can improve how stem cells help heal skin.
research Modeling Cell-Cell Communication for Immune Systems Across Space and Time
The document concludes that computational models are useful for understanding immune responses and could improve cancer immunotherapy.
research Insights into the Regeneration of Skin from Acomys, the Spiny Mouse
The spiny mouse can regenerate its skin without scarring, which could help us learn how to heal human skin better.
research Fibroblast Heterogeneity and Functions: Insights from Single-Cell Sequencing in Wound Healing, Breast Cancer, Ovarian Cancer, and Melanoma
Different types of fibroblasts play specific roles in wound healing and cancer, which could help improve treatments.
research Multi-View Light Sheet Fluorescence Microscopy for Imaging Cellular Self-Assembly in Spheroids of Human Hair Follicle Dermal Papilla Cells and Keratinocytes
The technique effectively shows how human skin and hair cells form into ball-like structures.
research Osteogenic Potential of Mesenchymal Stem Cells from Adipose Tissue, Bone Marrow, and Hair Follicle Outer Root Sheath in a 3D Crosslinked Gelatin-Based Hydrogel
Stem cells from hair follicles in a special gel show strong potential for bone regeneration.
research The Influence of a Biofilm-Dispersing Wound Gel on the Wound Healing Process
The biofilm-dispersing wound gel helps wounds heal faster and prevents infection.
research Scarless Wound Healing: Finding the Right Cells and Signals
The right cells and signals can potentially lead to scarless wound healing, with a mix of natural and external wound healing controllers possibly being the best way to achieve this.
research Injectable Silk Nanofiber Hydrogels as Stem Cell Carriers to Accelerate Wound Healing
Silk nanofiber hydrogels help stem cells heal wounds faster and improve skin regeneration.
research Skin Fibroblast Functional Heterogeneity in Health and Disease
Different types of skin fibroblasts have unique roles in skin health and disease.
research Cellular Therapeutics and Immunotherapies in Wound Healing – On the Pulse of Time?
Cellular and immunotherapies show promise for healing chronic wounds but need more research.
research Hierarchically Assembled Nanofiber Scaffolds With Dual Growth Factor Gradients Promote Skin Wound Healing Through Rapid Cell Recruitment
The new scaffold with two growth factors speeds up skin healing and reduces scarring.
research Autologous Stromal Vascular Fraction Cells Combined with Platelet-Rich Plasma for Androgenic Alopecia Treatment: A Case Series
The treatment led to denser, thicker hair growth and less hair loss.
research Human Macrophages Preferentially Infiltrate the Superficial Adipose Tissue
Human body's immune cells are more common in the layer of fat just beneath the skin than in deeper fat layers.
research A Novel Small Compound HPH-15 Antagonizes TGF-β/Smad Signaling and Ameliorates Experimental Skin Fibrosis
HPH-15, a new compound, effectively reduces skin fibrosis in experiments without causing harm.
research Pregnancy in Postpartum Estrus Induces Inflammatory Milk Production and Catagen-Specific Pup Skin Inflammation in Interleukin-10 Deficient Mice
Pregnancy right after giving birth in mice lacking IL-10 causes milk that leads to liver issues and hair loss in their babies.
research Minoxidil Is a Potential Neuroprotective Drug for Paclitaxel-Induced Peripheral Neuropathy
Minoxidil may protect nerves and improve hair quality during paclitaxel treatment.
research Use of Ultra-Fast One-Step CK5 IHC for Identifying BCC and SCC During Mohs Surgery
A new one-step test can quickly identify skin cancer during surgery.
research Structural Changes in Human Skin After Topical Application of Glucocorticoids Assessed by In Vivo Imaging Technologies
Topical glucocorticoids thin the skin and change collagen structure.
research Down-Regulatory Role of Cholecystokinin on Psoriatic Epidermal Inflammation
Cholecystokinin may help reduce skin inflammation in psoriasis.
research Deep Phenotyping of Patients with Xeroderma Pigmentosum and Trichothiodystrophy
Deep phenotyping helps distinguish between xeroderma pigmentosum and trichothiodystrophy, aiding in diagnosis and treatment.
research The Role of Local and Systemic Leptin in Androgenetic Alopecia
Higher leptin levels link to hair loss.