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Preliminary Pharmacokinetics and Metabolism of Novel Non-Steroidal Antiandrogens in the Rat: Relation of Their Systemic Activity to the Formation of a Common Metabolite

research Preliminary Pharmacokinetics and Metabolism of Novel Non-Steroidal Antiandrogens in the Rat: Relation of Their Systemic Activity to the Formation of a Common Metabolite

16 citations, October 1994 in “The Journal of Steroid Biochemistry and Molecular Biology”

Two non-steroidal antiandrogens, RU 58841 and RU 56187, form a common metabolite at different rates, which may influence their effects; RU 56187 could be used for prostate cancer treatment and RU 58841 for acne treatment.

research Geranylated Coumarins From Thai Medicinal Plant Mammea Siamensis With Testosterone 5α-Reductase Inhibitory Activity

17 citations, March 2020 in “Frontiers in Chemistry”

Compounds from the plant Mammea siamensis may help treat hair loss.

The 5alpha-Reductase Type 1, But Not Type 2, Gene Is Expressed in Anagen Hairs Plucked from the Vertex Area of the Scalp of Hirsute Women and Normal Individuals

research The 5alpha-Reductase Type 1, But Not Type 2, Gene Is Expressed in Anagen Hairs Plucked from the Vertex Area of the Scalp of Hirsute Women and Normal Individuals

17 citations, October 2003 in “Brazilian Journal of Medical and Biological Research”

The gene SDR5A1 is found in scalp hair of both hirsute and normal individuals, but it does not explain differences in hair growth.

research Influence of Melatonin on HaCaT Cell Proliferation Measured by Means of ATP Bioluminescence and Fluorometric Assays

November 2002

Melatonin affects cell growth differently based on its concentration.

research Finasteride: A Slow-Binding 5-Alpha-Reductase Inhibitor

70 citations, June 1993 in “Biochemistry”

Finasteride slowly binds to 5-alpha-reductase, affecting enzyme stability and inhibitor potency.

Production and Characterization of Wool and Hair Fibers in Highlands of Baluchistan: An Economic and Sustainable Approach for Pakistan

research Production and Characterization of Wool and Hair Fibers in Highlands of Baluchistan: An Economic and Sustainable Approach for Pakistan

9 citations, November 2015 in “Key Engineering Materials”

Improving skills and technology in Baluchistan's wool industry could boost quality, jobs, and Pakistan's economy.

Thyroid Hormones Directly Alter Human Hair Follicle Functions: Anagen Prolongation and Stimulation of Both Hair Matrix Keratinocyte Proliferation and Hair Pigmentation

research Thyroid Hormones Directly Alter Human Hair Follicle Functions: Anagen Prolongation and Stimulation of Both Hair Matrix Keratinocyte Proliferation and Hair Pigmentation

115 citations, August 2008 in “The Journal of Clinical Endocrinology & Metabolism”

Thyroid hormones help hair grow, reduce hair loss, and increase hair pigment.

research Pharmacokinetics of Finasteride in Elderly Volunteers

1 citations, January 1995 in “Yakubutsu dōtai”

research A General Mathematical Model for the In Vitro Assembly Dynamics of Intermediate Filament Proteins

5 citations, February 2022 in “Biophysical journal”

The model shows that filament flexibility and amino acid differences affect how fast intermediate filament proteins assemble.

research Synthesis, Anticancer, and Molecular Docking Studies of 2-(4-Chlorophenyl)-5-Aryl-1,3,4-Oxadiazole Analogues

8 citations, January 2013 in “Medicinal chemistry”

The compound 4c showed strong potential as an anticancer agent.

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